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4QT4
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Crystal structure of Peptidyl-tRNA hydrolase from a Gram-positive bacterium, Streptococcus pyogenes at 2.19 Angstrom resolution shows the Closed Structure of the Substrate Binding Cleft
Descriptor: Peptidyl-tRNA hydrolase
Authors:Singh, A, Gautam, L, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2014-07-07
Release date:2014-08-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, Streptococcus pyogenes at 2.19 angstrom resolution shows the closed structure of the substrate-binding cleft.
FEBS Open Bio, 4, 2014
3TD6
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Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis from trigonal partially dehydrated crystal
Descriptor: Peptidyl-tRNA hydrolase
Authors:Selvaraj, M, Ahmad, R, Varshney, U, Vijayan, M.
Deposit date:2011-08-10
Release date:2012-02-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule
Acta Crystallogr.,Sect.F, 68, 2012
4JFA
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Crystal Structure of Plasmodium falciparum Tryptophanyl-tRNA synthetase
Descriptor: BETA-MERCAPTOETHANOL, POTASSIUM ION, TRYPTOPHAN, ...
Authors:Khan, S, Garg, A, Manickam, Y, Sharma, A.
Deposit date:2013-02-28
Release date:2014-01-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An appended domain results in an unusual architecture for malaria parasite tryptophanyl-tRNA synthetase
Plos One, 8, 2013
4H02
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Crystal structure of P. falciparum Lysyl-tRNA synthetase
Descriptor: Lysyl-tRNA synthetase
Authors:Khan, S, Garg, A, Sharma, A.
Deposit date:2012-09-07
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.905 Å)
Cite:Structural analysis of malaria-parasite lysyl-tRNA synthetase provides a platform for drug development.
Acta Crystallogr.,Sect.D, 69, 2013
3KJZ
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Crystal structure of native peptidyl-tRNA hydrolase from Mycobacterium smegmatis
Descriptor: Peptidyl-tRNA hydrolase
Authors:Kumar, A, Singh, N, Yadav, R, Prem Kumar, R, Sharma, S, Arora, A, Singh, T.P.
Deposit date:2009-11-04
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from mycobacterium smegmatis reveals novel features related to enzyme dynamics.
Int J Biochem Mol Biol, 3, 2012
2HZ7
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Crystal structure of the Glutaminyl-tRNA synthetase from Deinococcus radiodurans
Descriptor: Glutaminyl-tRNA synthetase
Authors:Deniziak, M, Sauter, C, Becker, H.D, Paulus, C, Giege, R, Kern, D.
Deposit date:2006-08-08
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Deinococcus glutaminyl-tRNA synthetase is a chimer between proteins from an ancient and the modern pathways of aminoacyl-tRNA formation
Nucleic Acids Res., 35, 2007
2J3M
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PROLYL-TRNA SYNTHETASE FROM ENTEROCOCCUS FAECALIS COMPLEXED WITH ATP, manganese and prolinol
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PROLYL-TRNA SYNTHETASE, ...
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain.
Structure, 14, 2006
2J3L
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Prolyl-tRNA synthetase from Enterococcus faecalis complexed with a prolyl-adenylate analogue ('5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE)
Descriptor: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, PROLYL-TRNA SYNTHETASE, SULFATE ION
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-11
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain.
Structure, 14, 2006
4K86
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Crystal structure of human prolyl-tRNA synthetase (apo form)
Descriptor: Proline--tRNA ligase, ZINC ION
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
2KQR
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Solution structure of the N-terminal domain (residues 1-111) of Brugia malayi asparaginyl-tRNA synthetase
Descriptor: Asparaginyl-tRNA synthetase, cytoplasmic
Authors:Volkman, B.F, Peterson, F.C, Kron, M.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-11-16
Release date:2009-12-15
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:A Hybrid Structural Model of the Complete Brugia malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
2Z2I
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Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis
Descriptor: Peptidyl-tRNA hydrolase
Authors:Selvaraj, M, Roy, S, Singh, N.S, Sangeetha, R, Varshney, U, Vijayan, M.
Deposit date:2007-05-22
Release date:2007-07-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Plasticity and Enzyme Action: Crystal Structures of Mycobacterium tuberculosis Peptidyl-tRNA Hydrolase
J.Mol.Biol., 372, 2007
2Z2J
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Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis
Descriptor: Peptidyl-tRNA hydrolase
Authors:Selvaraj, M, Roy, S, Singh, N.S, Sangeetha, R, Varshney, U, Vijayan, M.
Deposit date:2007-05-22
Release date:2007-07-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Plasticity and Enzyme Action: Crystal Structures of Mycobacterium tuberculosis Peptidyl-tRNA Hydrolase
J.Mol.Biol., 372, 2007
2ZZF
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Crystal structure of alanyl-tRNA synthetase without oligomerization domain
Descriptor: Alanyl-tRNA synthetase, ZINC ION
Authors:Sokabe, M, Ose, T, Tokunaga, K, Nakamura, A, Nureki, O, Yao, M, Tanaka, I.
Deposit date:2009-02-10
Release date:2009-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of alanyl-tRNA synthetase with editing domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZZE
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Crystal structure of alanyl-tRNA synthetase without oligomerization domain in lysine-methylated form
Descriptor: Alanyl-tRNA synthetase, ZINC ION
Authors:Sokabe, M, Ose, T, Tokunaga, K, Nakamura, A, Nureki, O, Yao, M, Tanaka, I.
Deposit date:2009-02-10
Release date:2009-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:The structure of alanyl-tRNA synthetase with editing domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
3ZIU
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Crystal structure of Mycoplasma mobile Leucyl-tRNA Synthetase with Leu-AMS in the active site
Descriptor: 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, LEUCYL-TRNA SYNTHETASE
Authors:Li, L, Palencia, A, Lukk, T, Li, Z, Luthey-Schulten, Z.A, Cusack, S, Martinis, S.A, Boniecki, M.T.
Deposit date:2013-01-10
Release date:2013-02-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Leucyl-tRNA Synthetase Editing Domain Functions as a Molecular Rheostat to Control Codon Ambiguity in Mycoplasma Pathogens.
Proc.Natl.Acad.Sci.USA, 110, 2013
7FG6
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Crystal structure of the Tyrosyl-tRNA synthetase (TyrRS) in Nanoarchaeum equitans
Descriptor: Tyrosine--tRNA ligase
Authors:Noguchi, H, Kamata, K, Park, S.Y, Tamura, K.
Deposit date:2021-07-26
Release date:2021-09-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Nanoarchaeum equitans tyrosyl-tRNA synthetase and its aminoacylation activity toward tRNA Tyr with an extra guanosine residue at the 5'-terminus.
Biochem.Biophys.Res.Commun., 575, 2021
2I4L
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Rhodopseudomonas palustris prolyl-tRNA synthetase
Descriptor: Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
1HC7
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Prolyl-tRNA synthetase from Thermus thermophilus
Descriptor: PROLYL-TRNA SYNTHETASE, ZINC ION
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-04-26
Release date:2001-06-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
1H4V
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HISTIDYL-TRNA SYNTHETASE from Thermus Thermophilus (ligand free)
Descriptor: HISTIDYL-TRNA SYNTHETASE, SULFATE ION
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2001-05-14
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
1FMT
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METHIONYL-TRNAFMET FORMYLTRANSFERASE FROM ESCHERICHIA COLI
Descriptor: METHIONYL-TRNA FMET FORMYLTRANSFERASE
Authors:Schmitt, E, Mechulam, Y.
Deposit date:1997-10-13
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase.
EMBO J., 15, 1996
1X56
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Crystal structure of asparaginyl-tRNA synthetase from Pyrococcus horikoshii
Descriptor: Asparaginyl-tRNA synthetase
Authors:Iwasaki, W, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2006-05-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Basis of the Water-assisted Asparagine Recognition by Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 360, 2006
1L0W
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Aspartyl-tRNA synthetase-1 from space-grown crystals
Descriptor: Aspartyl-tRNA synthetase
Authors:Ng, J.D, Sauter, C, Lorber, B, Kirkland, N, Arnez, J, Giege, R.
Deposit date:2002-02-14
Release date:2002-03-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Comparative analysis of space-grown and earth-grown crystals of an aminoacyl-tRNA synthetase: space-grown crystals are more useful for structural determination.
Acta Crystallogr.,Sect.D, 58, 2002
2XGT
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Asparaginyl-tRNA synthetase from Brugia malayi complexed with the sulphamoyl analogue of asparaginyl-adenylate
Descriptor: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC, ...
Authors:Crepin, T, Haertlein, M, Kron, M, Cusack, S.
Deposit date:2010-06-07
Release date:2010-12-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
1WNY
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Isoleucyl-tRNA synthetase editing domain
Descriptor: isoleucyl-trna synthetase
Authors:Fukunaga, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-08-11
Release date:2005-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase
J.Mol.Biol., 359, 2006
3E9I
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Lysyl-tRNA synthetase from Bacillus stearothermophilus complexed with L-Lysine hydroxamate-AMP
Descriptor: 5'-O-{(R)-hydroxy[(L-lysylamino)oxy]phosphoryl}adenosine, Lysyl-tRNA synthetase, MAGNESIUM ION, ...
Authors:Sakurama, H, Takita, T, Mikami, B, Itoh, T, Yasukawa, K, Inouye, K.
Deposit date:2008-08-22
Release date:2009-07-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two crystal structures of lysyl-tRNA synthetase from Bacillus stearothermophilus in complex with lysyladenylate-like compounds: insights into the irreversible formation of the enzyme-bound adenylate of L-lysine hydroxamate
J.Biochem., 145, 2009

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數據於2024-07-10公開中

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