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6XLL
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BU of 6xll by Molmil
Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt)
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yang, Y, Liu, C, Liu, B.
Deposit date:2020-06-28
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XH7
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BU of 6xh7 by Molmil
CueR-TAC without RNA
Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W, Yang, Y.
Deposit date:2020-06-18
Release date:2021-04-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
6XH8
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BU of 6xh8 by Molmil
CueR-transcription activation complex with RNA transcript
Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W, Yang, Y.
Deposit date:2020-06-18
Release date:2021-04-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
7BEG
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BU of 7beg by Molmil
Structures of class I bacterial transcription complexes
Descriptor: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ...
Authors:Ye, F.Z, Hao, M, Zhang, X.D.
Deposit date:2020-12-23
Release date:2021-12-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
7BEF
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BU of 7bef by Molmil
Structures of class II bacterial transcription complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hao, M, Ye, F.Z, Zhang, X.D.
Deposit date:2020-12-23
Release date:2021-12-01
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
8W8O
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BU of 8w8o by Molmil
Thermus thermophilus initiation complex in the half-translocated state
Descriptor: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Li, L, Zhang, Y.
Deposit date:2023-09-04
Release date:2024-07-24
Method:X-RAY DIFFRACTION (2.512 Å)
Cite:Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
8W8P
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BU of 8w8p by Molmil
Thermus thermophilus initiation transcription complex containing CMPcPP in the post-translocated state
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (21-MER), DNA (27-MER), ...
Authors:Li, L, Zhang, Y.
Deposit date:2023-09-04
Release date:2024-07-24
Method:X-RAY DIFFRACTION (3.165 Å)
Cite:Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
8W8N
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BU of 8w8n by Molmil
Thermus thermophilus initiation transcription complex in the pre-translocated state
Descriptor: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Li, L, Zhang, Y.
Deposit date:2023-09-04
Release date:2024-07-24
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
7DY6
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BU of 7dy6 by Molmil
A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA
Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W.
Deposit date:2021-01-20
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation.
Biochem.Biophys.Res.Commun., 583, 2021
8U3B
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BU of 8u3b by Molmil
Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A
Descriptor: DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Kompaniiets, D, Wang, D.
Deposit date:2023-09-07
Release date:2024-01-17
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural basis for transcription activation by the nitrate-responsive regulator NarL.
Nucleic Acids Res., 52, 2024
7F75
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BU of 7f75 by Molmil
Cryo-EM structure of Spx-dependent transcription activation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-06-28
Release date:2021-10-13
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of transcription activation by the global regulator Spx.
Nucleic Acids Res., 49, 2021
8X6F
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BU of 8x6f by Molmil
Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex
Descriptor: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yuan, L, Xu, L, Liu, Q, Feng, Y.
Deposit date:2023-11-21
Release date:2024-06-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
8X6G
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BU of 8x6g by Molmil
Cryo-EM structure of Staphylococcus aureus sigB-dependent RNAP-promoter open complex
Descriptor: DNA (70-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yuan, L, Xu, L, Liu, Q, Feng, Y.
Deposit date:2023-11-21
Release date:2024-06-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
7EH0
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BU of 7eh0 by Molmil
Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ...
Authors:Li, L, Zhang, Y.
Deposit date:2021-03-27
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.808 Å)
Cite:Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
7EH2
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BU of 7eh2 by Molmil
Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer
Descriptor: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Li, L, Zhang, Y.
Deposit date:2021-03-27
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
7EH1
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BU of 7eh1 by Molmil
Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP
Descriptor: 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ...
Authors:Li, L, Zhang, Y.
Deposit date:2021-03-27
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
7CKQ
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BU of 7ckq by Molmil
The cryo-EM structure of B. subtilis BmrR transcription activation complex
Descriptor: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Fang, C.L, Zhang, Y.
Deposit date:2020-07-18
Release date:2020-12-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription.
Nat Commun, 11, 2020
7C97
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BU of 7c97 by Molmil
Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA
Descriptor: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W, Feng, Y.
Deposit date:2020-06-05
Release date:2020-08-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structural basis for transcription inhibition by E. coli SspA
Nucleic Acids Res., 2020
7CHW
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BU of 7chw by Molmil
Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo)
Descriptor: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lin, W, Feng, Y.
Deposit date:2020-07-06
Release date:2020-08-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structural basis for transcription inhibition by E. coli SspA
Nucleic Acids Res., 2020
7F0R
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BU of 7f0r by Molmil
Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex
Descriptor: DNA (70-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:He, D.W, You, L.L, Zhang, Y.
Deposit date:2021-06-06
Release date:2022-07-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Nat Commun, 13, 2022
7W5Y
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BU of 7w5y by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7W5W
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BU of 7w5w by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7W5X
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BU of 7w5x by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7XYA
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BU of 7xya by Molmil
The cryo-EM structure of an AlpA-loading complex
Descriptor: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Wen, A, Feng, Y.
Deposit date:2022-06-01
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of AlpA-dependent transcription antitermination.
Nucleic Acids Res., 50, 2022
7XUI
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BU of 7xui by Molmil
Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Hwang, S, Kang, J.Y.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA.
Nat Commun, 13, 2022

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數據於2024-09-11公開中

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