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8D7U
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BU of 8d7u by Molmil
Cereblon~DDB1 bound to CC-92480 with DDB1 in the linear conformation
Descriptor: DNA damage-binding protein 1, Mezigdomide, Protein cereblon, ...
Authors:Watson, E.R, Lander, G.C.
Deposit date:2022-06-07
Release date:2022-07-20
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science, 378, 2022
8DH6
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BU of 8dh6 by Molmil
Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs
Descriptor: CALCIUM ION, COPPER (II) ION, Cytochrome c oxidase subunit 1, ...
Authors:Godoy, A.S, Song, Y, Cheruvara, H, Quigley, A, Oliva, G.
Deposit date:2022-06-25
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs
To Be Published
8D81
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BU of 8d81 by Molmil
Cereblon~DDB1 bound to Pomalidomide
Descriptor: DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ...
Authors:Watson, E.R, Lander, G.C.
Deposit date:2022-06-07
Release date:2022-07-20
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science, 378, 2022
2HZK
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BU of 2hzk by Molmil
Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its open form
Descriptor: GLYCEROL, TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, ...
Authors:Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D.
Deposit date:2006-08-09
Release date:2007-04-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding.
Bmc Struct.Biol., 7, 2007
1YAG
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BU of 1yag by Molmil
STRUCTURE OF THE YEAST ACTIN-HUMAN GELSOLIN SEGMENT 1 COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Vorobiev, S, Strokopytov, B, Frieden, C, Almo, S.C.
Deposit date:1998-10-09
Release date:1999-10-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of nonvertebrate actin: Implications for the ATP hydrolytic mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
2I42
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BU of 2i42 by Molmil
Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
Descriptor: Tyrosine-protein phosphatase, VANADATE ION
Authors:Vijayalakshmi, J, Saper, M.A.
Deposit date:2006-08-21
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
To be Published
8A5O
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BU of 8a5o by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of S. cerevisiae INO80
Descriptor: Actin, Actin-like protein ARP8, Actin-related protein 4, ...
Authors:Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
Deposit date:2022-06-15
Release date:2022-12-14
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
1Y4D
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BU of 1y4d by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59R/E60S mutant
Descriptor: CALCIUM ION, SODIUM ION, chymotrypsin inhibitor 2, ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-30
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
2I5Q
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BU of 2i5q by Molmil
Crystal structure of Apo L-rhamnonate dehydratase from Escherichia Coli
Descriptor: L-rhamnonate dehydratase
Authors:Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-25
Release date:2006-09-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase.
Biochemistry, 47, 2008
8D7Y
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BU of 8d7y by Molmil
Cereblon-DDB1 in the Apo form with DDB1 in the twisted conformation
Descriptor: DNA damage-binding protein 1, Protein cereblon, ZINC ION
Authors:Watson, E.R, Lander, G.C.
Deposit date:2022-06-07
Release date:2022-07-20
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science, 378, 2022
2I68
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BU of 2i68 by Molmil
Cryo-EM based theoretical model structure of transmembrane domain of the multidrug-resistance antiporter from E. coli EmrE
Descriptor: Protein emrE
Authors:Fleishman, S.J, Harrington, S.E, Enosh, A, Halperin, D, Tate, C.G, Ben-Tal, N.
Deposit date:2006-08-28
Release date:2006-10-03
Last modified:2024-03-13
Method:ELECTRON CRYSTALLOGRAPHY (7.5 Å)
Cite:Quasi-symmetry in the Cryo-EM Structure of EmrE Provides the Key to Modeling its Transmembrane Domain
J.Mol.Biol., 364, 2006
1YK0
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BU of 1yk0 by Molmil
structure of natriuretic peptide receptor-C complexed with atrial natriuretic peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Atrial natriuretic factor, ...
Authors:He, X, Garcia, K.C.
Deposit date:2005-01-16
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural determinants of natriuretic peptide receptor specificity and degeneracy.
J.Mol.Biol., 361, 2006
2IAN
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BU of 2ian by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
1YKC
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BU of 1ykc by Molmil
human glutathione S-transferase m2-2 (E.C.2.5.1.18) complexed with glutathione-disulfide
Descriptor: Glutathione S-transferase Mu 2, OXIDIZED GLUTATHIONE DISULFIDE
Authors:Patskovsky, Y.V, Patskovska, L.N, Listowsky, I, Almo, S.C.
Deposit date:2005-01-17
Release date:2005-01-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective Inhibitors of Prostaglandin Synthase activity of human glutathione S-transferase M2-2
To be Published
1Y9M
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BU of 1y9m by Molmil
Crystal structure of exo-inulinase from Aspergillus awamori in spacegroup P212121
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Nagem, R.A.P, Rojas, A.L, Golubev, A.M, Korneeva, O.S, Eneyskaya, E.V, Kulminskaya, A.A, Neustroev, K.N, Polikarpov, I.
Deposit date:2004-12-16
Release date:2004-12-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of exo-inulinase from Aspergillus awamori: the enzyme fold and structural determinants of substrate recognition
J.Mol.Biol., 344, 2004
8A5D
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BU of 8a5d by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80
Descriptor: Actin, Actin related protein 4 (Arp4), Actin-related protein 8, ...
Authors:Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
Deposit date:2022-06-14
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
2IA8
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BU of 2ia8 by Molmil
Kinetic and Crystallographic Studies of a Redesigned Manganese-Binding Site in Cytochrome c Peroxidase
Descriptor: Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pfister, T, Mirarefi, A.Y, Gengenbach, A.J, Zhao, X, Conaster, C.D.N, Gao, Y.G, Robinson, H, Zukoski, C.F, Wang, A.H.J, Lu, Y.
Deposit date:2006-09-07
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase
J.Biol.Inorg.Chem., 12, 2007
8D7W
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BU of 8d7w by Molmil
Cereblon~DDB1 bound to CC-92480 with DDB1 in the hinged conformation
Descriptor: DNA damage-binding protein 1, Mezigdomide, Protein cereblon, ...
Authors:Watson, E.R, Lander, G.C.
Deposit date:2022-06-07
Release date:2022-07-20
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science, 378, 2022
8CTJ
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BU of 8ctj by Molmil
Cryo-EM structure of TMEM87A
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Transmembrane protein 87A
Authors:Hoel, C.M, Zhang, L, Brohawn, S.G.
Deposit date:2022-05-15
Release date:2022-07-20
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (4.74 Å)
Cite:Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A.
Elife, 11, 2022
7ZTC
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BU of 7ztc by Molmil
Non-muscle F-actin decorated with non-muscle tropomyosin 1.6
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 1.6, actin, ...
Authors:Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T.
Deposit date:2022-05-09
Release date:2023-01-11
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms.
Cell Rep, 42, 2023
8CVP
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BU of 8cvp by Molmil
Cereblon-DDB1 in the Apo form
Descriptor: DNA damage-binding protein 1, Protein cereblon, ZINC ION
Authors:Watson, E.R, Lander, G.C.
Deposit date:2022-05-18
Release date:2022-07-20
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science, 378, 2022
7ZTD
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BU of 7ztd by Molmil
Non-muscle F-actin decorated with non-muscle tropomyosin 3.2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 3.2, actin, ...
Authors:Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T.
Deposit date:2022-05-09
Release date:2023-01-11
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms.
Cell Rep, 42, 2023
8D7V
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BU of 8d7v by Molmil
Cereblon~DDB1 bound to CC-92480 with DDB1 in the twisted conformation
Descriptor: DNA damage-binding protein 1, Mezigdomide, Protein cereblon, ...
Authors:Watson, E.R, Lander, G.C.
Deposit date:2022-06-07
Release date:2022-07-20
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science, 378, 2022
8D7Z
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BU of 8d7z by Molmil
Cereblon-DDB1 bound to CC-92480 and Ikaros ZF1-2-3
Descriptor: DNA damage-binding protein 1, DNA-binding protein Ikaros, Mezigdomide, ...
Authors:Watson, E.R, Lander, G.C.
Deposit date:2022-06-07
Release date:2022-07-20
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular glue CELMoD compounds are regulators of cereblon conformation.
Science, 378, 2022
2JKE
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BU of 2jke by Molmil
Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin
Descriptor: 1,2-ETHANEDIOL, 1-DEOXYNOJIRIMYCIN, ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), ...
Authors:Gloster, T.M, Turkenburg, J.P, Potts, J.R, Henrissat, B, Davies, G.J.
Deposit date:2008-08-28
Release date:2008-09-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.
Chem.Biol., 15, 2008

224572

數據於2024-09-04公開中

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