8CVP

Cereblon-DDB1 in the Apo form

Summary for 8CVP

• Entry DOI: 10.2210/pdb8cvp/pdb
• Related: 8d7u 8d7v 8d7w 8d7x 8d7y 8d7z 8d80 8d81
• EMDB information: 27012
• Descriptor: DNA damage-binding protein 1, Protein cereblon, ZINC ION (3 entities in total)
• Functional Keywords: ubiquitin, crl4, adaptor, cereblon, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 177766.55

Authors

Watson, E.R.,Lander, G.C. (deposition date: 2022-05-18, release date: 2022-07-20, Last modification date: 2023-04-05)

• Primary citation: Watson, E.R.,Novick, S.,Matyskiela, M.E.,Chamberlain, P.P.,H de la Pena, A.,Zhu, J.,Tran, E.,Griffin, P.R.,Wertz, I.E.,Lander, G.C.; Molecular glue CELMoD compounds are regulators of cereblon conformation.; Science, 378:549-553, 2022; PubMed: 36378961; DOI: 10.1126/science.add7574

Experimental method

ELECTRON MICROSCOPY (3.4 Å)