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5IUE
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Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP, ...
Authors:Dulberger, C.L, Adams, E.J.
Deposit date:2016-03-17
Release date:2017-06-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.
Immunity, 46, 2017
5GRD
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BU of 5grd by Molmil
Crystal structure of 10-mer peptide from EBV in complex with HLA-A1101.
Descriptor: Beta-2-microglobulin, Epstein Barr Virus, Latent membrane protein 2 epitope, ...
Authors:Tadwal, V.S, Xiao, Z, Ren, E.C.
Deposit date:2016-08-10
Release date:2017-08-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens
Sci Rep, 7, 2017
5IVX
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BU of 5ivx by Molmil
Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Natarajan, K, Jiang, J, Margulies, D.
Deposit date:2016-03-21
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
5IB3
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BU of 5ib3 by Molmil
Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR and Copper
Descriptor: Beta-2-microglobulin, COPPER (II) ION, GLYCEROL, ...
Authors:Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B.
Deposit date:2016-02-22
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
5J6G
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Recognition of the MHC class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, Q10 alpha chain, ...
Authors:Berry, R, Rossjohn, J.
Deposit date:2016-04-04
Release date:2016-07-13
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.
J.Biol.Chem., 291, 2016
2BSS
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BU of 2bss by Molmil
Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B2705
Descriptor: BETA-2-MICROGLOBULIN, HIV PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-27 ALPHA CHAIN
Authors:Stewart-Jones, G.B.E, Di Gleria, K, Kollnberger, S, Mcmichael, A.J, Jones, E.Y, Bowness, P.
Deposit date:2005-05-23
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
2BVO
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Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression
Descriptor: BETA-2-MICROGLOBULIN, GAG PROTEIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y.
Deposit date:2005-07-01
Release date:2005-09-13
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
J Immunol., 175, 2005
2BSR
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Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B2705
Descriptor: BETA-2-MICROGLOBULIN, EPSTEIN-BARR NUCLEAR ANTIGEN-6, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Stewart-Jones, G.B.E, Di Gleria, K, Kollnberger, S, Mcmichael, A.J, Jones, E.Y, Bowness, P.
Deposit date:2005-05-23
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
2BNQ
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
2BNR
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
Authors:Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
Deposit date:2005-03-31
Release date:2005-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
2BVP
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BU of 2bvp by Molmil
Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression
Descriptor: BETA-2-MICROGLOBULIN, HIV-P24, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y.
Deposit date:2005-07-01
Release date:2005-09-07
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
J Immunol., 175, 2005
2BST
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BU of 2bst by Molmil
Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B2705
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 ALPHA CHAIN PRECURSOR, ...
Authors:Stewart-Jones, G.B.E, diGleria, K, Kollnberger, S, McMichael, A.J, Bowness, P, Jones, E.Y.
Deposit date:2005-05-23
Release date:2005-05-24
Last modified:2015-05-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures and Kir3Dl1 Recognition of Three Immunodominant Viral Peptides Complexed to Hla-B2705
Eur.J.Immunol., 35, 2005
2CLR
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THREE DIMENSIONAL STRUCTURE OF A PEPTIDE EXTENDING OUT ONE END OF A CLASS I MHC BINDING SITE
Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) (ALPHA CHAIN), DECAMERIC PEPTIDE FROM CALRETICULIN
Authors:Collins, E.J, Garboczi, D.N, Wiley, D.C.
Deposit date:1994-08-01
Release date:1995-03-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a peptide extending from one end of a class I MHC binding site.
Nature, 371, 1994
2CII
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The crystal structure of H-2Db complexed with a partial peptide epitope suggests an MHC Class I assembly-intermediate
Descriptor: BETA-2-MICROGLOBULIN, GLYCEROL, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, ...
Authors:Glithero, A, Tormo, J, Doering, K, Kojima, M, Jones, E.Y, Elliott, T.
Deposit date:2006-03-21
Release date:2006-03-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate.
J. Biol. Chem., 281, 2006
2CLZ
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BU of 2clz by Molmil
Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and pBM1 peptide
Descriptor: BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, ...
Authors:Mazza, C, Auphan-Anezin, N, Guimezanes, A, Barrett-Wilt, G.A, Montero-Julian, F, Roussel, A, Hunt, D.F, Schmitt-Verhulst, A.M, Malissen, B.
Deposit date:2006-05-03
Release date:2006-06-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Orientation of the Alloreactive Monoclonal Cd8 T Cell Activation Program by Three Different Peptide/Mhc Complexes.
Eur.J.Immunol., 36, 2006
2CLV
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MHC Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and pBM8 peptide
Descriptor: BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, ...
Authors:Mazza, C, Auphan-Anezin, N, Guimezanes, A, Barrett-Wilt, G.A, Montero-Julian, F, Roussel, A, Hunt, D.F, Schmitt-Verhulst, A.M, Malissen, B.
Deposit date:2006-05-02
Release date:2006-06-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes.
Eur. J. Immunol., 36, 2006
2BVQ
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BU of 2bvq by Molmil
Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression
Descriptor: BETA-2-MICROGLOBULIN, HIV-P24, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y.
Deposit date:2005-07-01
Release date:2005-09-07
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
J Immunol., 175, 2005
2C7U
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Conflicting selective forces affect CD8 T-cell receptor contact sites in an HLA-A2 immunodominant HIV epitope.
Descriptor: BETA-2-MICROGLOBULIN, GAG PROTEIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Iversen, A.K, Stewart-Jones, G, Learn, G.H, Christie, N, Sylvester-Hviid, C, Armitage, A.E, Kaul, R, Beattie, T, Lee, J.K, Li, Y, Chotiyarnwong, P, Dong, T, Xu, X, Luscher, M.A, MacDonald, K, Ullum, H, Klarlund-Pedersen, B, Skinhoj, P, Fugger, J.L, Buus, S, Mullins, J.I, Jones, E.Y, van der Merwe, P.A, McMichael, A.J.
Deposit date:2005-11-29
Release date:2006-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Conflicting Selective Forces Affect T Cell Receptor Contacts in an Immunodominant Human Immunodeficiency Virus Epitope.
Nat.Immunol., 7, 2006
2AV7
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BU of 2av7 by Molmil
Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the K66A mutation in the heavy chain.
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2005-08-29
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
J.Mol.Biol., 353, 2005
2DYP
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BU of 2dyp by Molmil
Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G
Descriptor: 9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K.
Deposit date:2006-09-15
Release date:2006-11-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
Proc.Natl.Acad.Sci.Usa, 103, 2006
2BCK
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BU of 2bck by Molmil
Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F.
Deposit date:2005-10-19
Release date:2006-01-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
2BC4
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Crystal structure of HLA-DM
Descriptor: CHLORIDE ION, HLA class II histocompatibility antigen, DM alpha chain, ...
Authors:Nicholson, M.J, Moradi, B, Seth, N.P, Xing, X, Cuny, G.D, Stein, R.L, Wucherpfennig, K.W.
Deposit date:2005-10-18
Release date:2006-05-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Small molecules that enhance the catalytic efficiency of HLA-DM.
J.Immunol., 176, 2006
2AXF
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The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation
Descriptor: 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ...
Authors:Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2005-09-05
Release date:2005-11-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
J.Exp.Med., 202, 2005
2AV1
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BU of 2av1 by Molmil
Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the E63Q and K66A mutations in the heavy chain.
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2005-08-29
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
J.Mol.Biol., 353, 2005
2AK4
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Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide
Descriptor: Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, HLA-B35 variant, ...
Authors:Tynan, F.E, Burrows, S.R, Buckle, A.M, Clements, C.S, Borg, N.A, Miles, J.J, Beddoe, T, Whisstock, J.C, Wilce, M.C, Silins, S.L, Burrows, J.M, Kjer-Nielsen, L, Konstenko, L, Purcell, A.W, McCluskey, J, Rossjohn, J.
Deposit date:2005-08-03
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005

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數據於2024-09-18公開中

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