PDB: 52399 resultsInfo pagesStatus searchChemie searchBIRD

---

8SJ1	Structure of ternary complex of cGAS with dsDNA and bound 3'-dATP Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-04-17 Release date: 2024-04-24 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.81 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SHZ	Structure of human cGAS Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Wu, S, Sohn, J. Deposit date: 2023-04-14 Release date: 2024-04-24 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SLF	Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound) Descriptor: ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, MAGNESIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-04-21 Release date: 2023-05-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound) To be published
8SLH	Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound, hexagonal form) Descriptor: ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, MAGNESIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-04-21 Release date: 2023-05-03 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Crystal Structure of Glycine tRNA ligase from Mycobacterium thermoresistibile (AMP bound, hexagonal form) To be published
6Y8C	Crystal structure of the cAMP-dependent protein kinase A cocrystallized with ATP and PKI (5-24) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DIMETHYL SULFOXIDE, ... Authors: Oebbeke, M, Heine, A, Klebe, G. Deposit date: 2020-03-04 Release date: 2020-09-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A crystallographic study of cAMP-dependent protein kinase A in complex with different Fasudil-derivatives To Be Published
6HQ3	Structure of EAL Enzyme Bd1971 - halfsite-occupied form Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, EAL Enzyme Bd1971 Authors: Lovering, A.L, Cadby, I.T. Deposit date: 2018-09-24 Release date: 2019-07-31 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Nucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase. Embo J., 38, 2019
6NFE	Crystal Structure of Ribose-phosphate Pyrophosphokinase from Legionella pneumophila with bound AMP, ADP, and Ribose-5-Phosphate Descriptor: 1,2-ETHANEDIOL, 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-12-19 Release date: 2019-01-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structure of Ribose-phosphate Pyrophosphokinase from Legionella pneumophila with bound AMP, ADP, and Ribose-5-Phosphate to be published
8VW0	Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (AMP bound) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-01-31 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of Apo UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli (AMP bound) To be published
9B20	Crystal structure of ADP-ribose diphosphatase from Klebsiella pneumoniae (AMP bound) Descriptor: ADENOSINE MONOPHOSPHATE, ADP-ribose pyrophosphatase, MAGNESIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-03-14 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal structure of ADP-ribose diphosphatase from Klebsiella pneumoniae (AMP bound) To be published
7BAQ	Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24) Descriptor: (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Oebbeke, M, Heine, A, Klebe, G. Deposit date: 2020-12-16 Release date: 2022-01-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24) To Be Published
7BB0	Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24) Descriptor: (R)-3,3-dimethyl-5-oxo-5-(6-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl)pentanoic acid, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Oebbeke, M, Mueller, J, Glinca, S, Heine, A, Klebe, G. Deposit date: 2020-12-16 Release date: 2022-01-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24) To Be Published
6YX5	Structure of DrrA from Legionella pneumophilia in complex with human Rab8a Descriptor: MAGNESIUM ION, Multifunctional virulence effector protein DrrA, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Schneider, S, Du, J, von Wrisberg, M.K, Lang, K, Itzen, A. Deposit date: 2020-04-30 Release date: 2020-12-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1. Nat Commun, 12, 2021
7BAR	Crystal structure of the cAMP-dependent protein kinase A with a chiral ligand (S- and E-configuration, soaked) Descriptor: (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium, cAMP-dependent protein kinase catalytic subunit alpha Authors: Oebbeke, M, Heine, A, Klebe, G. Deposit date: 2020-12-16 Release date: 2022-01-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Crystal structure of the cAMP-dependent protein kinase A with a chiral ligand (S- and E-configuration, soaked) To Be Published
3S22	AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with an inhibitor Descriptor: Beta-lactamase, CHLORIDE ION, [(2S,3R)-2-formyl-1-{[4-(methylamino)butyl]carbamoyl}pyrrolidin-3-yl]sulfamic acid Authors: Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. Deposit date: 2011-05-16 Release date: 2011-06-29 Last modified: 2013-06-26 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
8G23	Structure of Ternary Complex of cGAS with dsDNA and Bound pppIpA Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-02-03 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.71 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIM	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.63 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIP	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.040mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIN	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.015mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8G1J	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and ITP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-02-02 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
7N8W	Crystal structure of ERI2 nuclease bound to rAMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 2, ... Authors: Thapar, R, Arvai, A.S, Tainer, J.A. Deposit date: 2021-06-15 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of ERI2 nuclease bound to rAMP To Be Published
1NJG	Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit Descriptor: DNA polymerase III subunit gamma, SULFATE ION, ZINC ION Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
1NJF	Nucleotide bound form of an isolated E. coli clamp loader gamma subunit Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
6S27	Crystal structure of human wild type STING in complex with 2'3'-cyclic-GMP-2'F-2'dAMP Descriptor: 2'3'-cyclic-GMP-2'F-2'dAMP, Stimulator of interferon protein Authors: Smola, M, Boura, E. Deposit date: 2019-06-20 Release date: 2019-11-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.802 Å) Cite: Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. J.Med.Chem., 62, 2019
9B22	Crystal structure of ADP-ribose diphosphatase from Klebsiella pneumoniae (ADP Ribose and AMP bound) Descriptor: ADENOSINE MONOPHOSPHATE, ADP-ribose pyrophosphatase, MAGNESIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2024-03-14 Release date: 2024-03-27 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal structure of ADP-ribose diphosphatase from Klebsiella pneumoniae (ADP Ribose and AMP bound) To be published
3I62	Structure of Mss116p bound to ssRNA and ADP-Aluminum Fluoride Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ... Authors: Del Campo, M, Lambowitz, A.M. Deposit date: 2009-07-06 Release date: 2009-09-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA Mol.Cell, 35, 2009

<68697071727374757677787980818283>