7ZWL

Crystal structure of human STING in complex with 3',3'-c-di-(2'F,2'dAMP)

Summary for 7ZWL

• Entry DOI: 10.2210/pdb7zwl/pdb
• Descriptor: Stimulator of interferon protein, Ubiquitin-like protein SMT3, 9-[(1~{R},6~{R},8~{R},9~{S},10~{R},15~{R},17~{R},18~{S})-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,11,13-tetraoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]purin-6-amine, ... (4 entities in total)
• Functional Keywords: sting, antiviral, activator, antiviral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 58241.11

Authors

Klima, M.,Smola, M.,Boura, E. (deposition date: 2022-05-19, release date: 2023-11-29)

• Primary citation: Klima, M.,Smola, M.,Boura, E.; Crystal structure of human STING in complex with 3',3'-c-di-(2'F,2'dAMP); To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)