6DWD
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![BU of 6dwd by Molmil](/molmil-images/mine/6dwd) | SAMHD1 Bound to Clofarabine-TP in the Catalytic Pocket and Allosteric Pocket | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, 9-{2-deoxy-2-fluoro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-2-me thyl-9H-purin-6-amine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | Authors: | Knecht, K.M, Buzovetsky, O, Schneider, C, Thomas, D, Srikanth, V, Kaderali, L, Tofoleanu, F, Reiss, K, Ferreiros, N, Geisslinger, G, Batista, V.S, Ji, X, Cinatl, J, Keppler, O.T, Xiong, Y. | Deposit date: | 2018-06-26 | Release date: | 2018-10-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XKD
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![BU of 5xkd by Molmil](/molmil-images/mine/5xkd) | Crystal structure of dibenzothiophene sulfone monooxygenase BdsA in complex with FMN at 2.4 angstrom | Descriptor: | Dibenzothiophene desulfurization enzyme A, FLAVIN MONONUCLEOTIDE | Authors: | Gu, L, Su, T, Liu, S, Su, J. | Deposit date: | 2017-05-07 | Release date: | 2018-05-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.393 Å) | Cite: | Structural and Biochemical Characterization of BdsA fromBacillus subtilisWU-S2B, a Key Enzyme in the "4S" Desulfurization Pathway. Front Microbiol, 9, 2018
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5B39
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![BU of 5b39 by Molmil](/molmil-images/mine/5b39) | KIR3DL1*015 in complex with HLA-B*57:01 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Vivian, J.P, Rossjohn, J. | Deposit date: | 2016-02-12 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition J.Exp.Med., 213, 2016
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5AYT
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![BU of 5ayt by Molmil](/molmil-images/mine/5ayt) | Crystal structure of transthyretin in complex with L6 | Descriptor: | 2-oxidanyl-6-(phenylcarbonyl)benzo[de]isoquinoline-1,3-dione, Transthyretin | Authors: | Yokoyama, T, Mizuguchi, M, Kai, H. | Deposit date: | 2015-09-03 | Release date: | 2016-01-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione J. Pharmacol. Sci., 129, 2015
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7MQ2
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![BU of 7mq2 by Molmil](/molmil-images/mine/7mq2) | |
7MQ3
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![BU of 7mq3 by Molmil](/molmil-images/mine/7mq3) | |
5XTA
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![BU of 5xta by Molmil](/molmil-images/mine/5xta) | Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila | Descriptor: | GLYCEROL, SULFATE ION, VirK protein | Authors: | Yin, S, Gong, X, Zhang, N, Ge, H. | Deposit date: | 2017-06-18 | Release date: | 2017-08-16 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila, reveals a novel fold for bacterial VirK proteins FEBS Lett., 591, 2017
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5UQE
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![BU of 5uqe by Molmil](/molmil-images/mine/5uqe) | Multidomain structure of human kidney-type glutaminase(KGA/GLS) | Descriptor: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | Authors: | Pasquali, C.C, Dias, S.M.G, Ambrosio, A.L.B. | Deposit date: | 2017-02-08 | Release date: | 2017-05-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. J. Biol. Chem., 292, 2017
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3HQQ
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5ZW2
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![BU of 5zw2 by Molmil](/molmil-images/mine/5zw2) | FAD complex of PigA | Descriptor: | 1,2-ETHANEDIOL, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ACETATE ION, ... | Authors: | Lee, C.-C, Ko, T.-P, Wang, A.H.J. | Deposit date: | 2018-05-14 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis. Chembiochem, 20, 2019
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6DD9
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![BU of 6dd9 by Molmil](/molmil-images/mine/6dd9) | Structure of mouse SYCP3, P1 form | Descriptor: | Synaptonemal complex protein 3 | Authors: | Rosenberg, S.C, Munoz, I.C, Uson, I, Corbett, K.D. | Deposit date: | 2018-05-09 | Release date: | 2018-08-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. Elife, 8, 2019
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3LD4
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![BU of 3ld4 by Molmil](/molmil-images/mine/3ld4) | Urate oxidase complexed with 8-nitro xanthine | Descriptor: | 1,2-ETHANEDIOL, 8-nitro-3,7-dihydro-1H-purine-2,6-dione, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N, Gabison, L. | Deposit date: | 2010-01-12 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand. Acta Crystallogr.,Sect.D, 66, 2010
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3LGA
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5DWB
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![BU of 5dwb by Molmil](/molmil-images/mine/5dwb) | Crystal structure of specific restriction endonuclease AgeI-DNA complex | Descriptor: | DNA (5'-D(*TP*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*GP*A*)-3'), Type-2 restriction enzyme AgeI | Authors: | Tamulaitiene, G, Jovaisaite, V, Grazulis, S, Siksnys, V. | Deposit date: | 2015-09-22 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA. Nucleic Acids Res., 45, 2017
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4BJ8
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![BU of 4bj8 by Molmil](/molmil-images/mine/4bj8) | Zebavidin | Descriptor: | BIOTIN, GLYCEROL, ZEBAVIDIN | Authors: | Airenne, T.T, Parthiban, M, Niederhauser, B, Zmurko, J, Kulomaa, M.S, Hytonen, V.P, Johnson, M.S. | Deposit date: | 2013-04-17 | Release date: | 2013-11-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Zebavidin Plos One, 8, 2013
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6DWK
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![BU of 6dwk by Molmil](/molmil-images/mine/6dwk) | SAMHD1 Bound to Fludarabine-TP in the Catalytic Pocket | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-fluoro-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-a mine, ... | Authors: | Knecht, K.M, Buzovetsky, O, Schneider, C, Thomas, D, Srikanth, V, Kaderali, L, Tofoleanu, F, Reiss, K, Ferreiros, N, Geisslinger, G, Batista, V.S, Ji, X, Cinatl, J, Keppler, O.T, Xiong, Y. | Deposit date: | 2018-06-26 | Release date: | 2018-10-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5E6C
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![BU of 5e6c by Molmil](/molmil-images/mine/5e6c) | Glucocorticoid receptor DNA binding domain - CCL2 NF-kB response element complex | Descriptor: | DNA (5'-D(*AP*GP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*CP*T)-3'), Glucocorticoid receptor, ... | Authors: | Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A. | Deposit date: | 2015-10-09 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements. Nat Commun, 9, 2018
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5E69
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![BU of 5e69 by Molmil](/molmil-images/mine/5e69) | Glucocorticoid receptor DNA binding domain - IL8 NF-kB response element complex | Descriptor: | DNA (5'-D(*AP*TP*CP*GP*TP*GP*GP*AP*AP*TP*TP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*AP*AP*TP*TP*CP*CP*AP*CP*GP*AP*T)-3'), Glucocorticoid receptor, ... | Authors: | Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A. | Deposit date: | 2015-10-09 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements. Nat Commun, 9, 2018
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5E6D
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![BU of 5e6d by Molmil](/molmil-images/mine/5e6d) | Glucocorticoid receptor DNA binding domain - ICAM1 NF-kB response element complex | Descriptor: | DNA (5'-D(*GP*CP*TP*CP*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*GP*GP*AP*GP*C)-3'), Glucocorticoid receptor, ... | Authors: | Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A. | Deposit date: | 2015-10-09 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements. Nat Commun, 9, 2018
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5ZW7
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![BU of 5zw7 by Molmil](/molmil-images/mine/5zw7) | FAD-PigA complex at 1.3 A | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Lee, C.-C, Ko, T.-P, Wang, A.H.J. | Deposit date: | 2018-05-14 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis. Chembiochem, 20, 2019
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6AF6
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![BU of 6af6 by Molmil](/molmil-images/mine/6af6) | PigA with FAD and proline | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Lee, C.-C, Ko, T.-P, Wang, A.H.J. | Deposit date: | 2018-08-08 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis. Chembiochem, 20, 2019
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5T30
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![BU of 5t30 by Molmil](/molmil-images/mine/5t30) | Human MnSOD-azide complex | Descriptor: | AZIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Azadmanesh, J, Trickel, S.R, Kolar, C.H, Lovelace, J.J, Borgstahl, G.E.O. | Deposit date: | 2016-08-24 | Release date: | 2017-05-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Substrate-analog binding and electrostatic surfaces of human manganese superoxide dismutase. J. Struct. Biol., 199, 2017
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3KGF
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![BU of 3kgf by Molmil](/molmil-images/mine/3kgf) | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan | Descriptor: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | Deposit date: | 2009-10-29 | Release date: | 2010-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis J.Biol.Chem., 285, 2010
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3L9G
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![BU of 3l9g by Molmil](/molmil-images/mine/3l9g) | Urate oxidase complexed with uric acid and chloride | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, SODIUM ION, ... | Authors: | Prange, T, Colloc'h, N, Gabison, L. | Deposit date: | 2010-01-05 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand. Acta Crystallogr.,Sect.D, 66, 2010
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5ZW0
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![BU of 5zw0 by Molmil](/molmil-images/mine/5zw0) | Apo-form PigA | Descriptor: | L-prolyl-[peptidyl-carrier protein] dehydrogenase | Authors: | Lee, C.-C, Ko, T.-P, Wang, A.H.J. | Deposit date: | 2018-05-14 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis. Chembiochem, 20, 2019
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