5E6D

Glucocorticoid receptor DNA binding domain - ICAM1 NF-kB response element complex

Summary for 5E6D

Related5E69 5E6A 5E6B 5E6C
DescriptorDNA (5'-D(*GP*CP*TP*CP*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*GP*GP*AP*GP*C)-3'), Glucocorticoid receptor, ... (5 entities in total)
Functional Keywordsdna binding proteins, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (Human)
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Total number of polymer chains4
Total molecular weight35577.63
Authors
Hudson, W.H.,Rye, E.A.,Herbst, A.G.,Ortlund, E.A. (deposition date: 2015-10-09, release date: 2017-02-08, Last modification date: 2018-10-24)
Primary citation
Hudson, W.H.,Vera, I.M.S.,Nwachukwu, J.C.,Weikum, E.R.,Herbst, A.G.,Yang, Q.,Bain, D.L.,Nettles, K.W.,Kojetin, D.J.,Ortlund, E.A.
Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements.
Nat Commun, 9:1337-1337, 2018
PubMed: 29626214 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-03780-1
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28319 0.7% 4.1% 11.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload