6TYN
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![BU of 6tyn by Molmil](/molmil-images/mine/6tyn) | Salmonella Typhi PltB Homopentamer with Neu-5NAc-9OAc-alpha-2-3-Gal-beta-1-4-GlcNAc Glycans | Descriptor: | 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertussis like toxin subunit B | Authors: | Nguyen, T, Milano, S.K, Yang, Y.A, Song, J. | Deposit date: | 2019-08-09 | Release date: | 2020-02-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. Plos Pathog., 16, 2020
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5DPX
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![BU of 5dpx by Molmil](/molmil-images/mine/5dpx) | 1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases. | Descriptor: | 5-(2-methylphenyl)-3H-1,2,4-triazole-3-thione, Metallo-beta-lactamase L1 type 3, SULFATE ION, ... | Authors: | Nauton, L, Garau, G, Khan, R, Dideberg, O. | Deposit date: | 2015-09-14 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases. ChemMedChem, 12, 2017
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7UYO
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7UYN
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7UYP
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5FWT
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![BU of 5fwt by Molmil](/molmil-images/mine/5fwt) | Wnt modulator Kremen crystal form I at 2.10A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, KREMEN PROTEIN 1, ... | Authors: | Zebisch, M, Jackson, V.A, Jones, E.Y. | Deposit date: | 2016-02-21 | Release date: | 2016-07-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf Structure, 24, 2016
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5DX8
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6I99
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![BU of 6i99 by Molmil](/molmil-images/mine/6i99) | Bone Marrow Tyrosine Kinase in Chromosome X in complex with a newly designed covalent inhibitor JS24 | Descriptor: | Cytoplasmic tyrosine-protein kinase BMX, ~{N}-[2-methyl-5-[8-[4-(methylsulfonylamino)phenyl]-2-oxidanylidene-benzo[h][1,6]naphthyridin-1-yl]phenyl]-3-oxidanyl-propanamide | Authors: | Sousa, B.B, Matias, P.M, Marques, M.C, Seixas, J.D, Bernardes, G.J.L. | Deposit date: | 2018-11-22 | Release date: | 2020-05-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors Chem.Biol., 2020
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8I8N
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![BU of 8i8n by Molmil](/molmil-images/mine/8i8n) | Crystal structure of the ternary complex of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with Dephosphocoenzyme-A and Phosphonoacetic acid at 2.22 A resolution. | Descriptor: | 1,2-ETHANEDIOL, DEPHOSPHO COENZYME A, GLYCEROL, ... | Authors: | Ahmad, N, Sharma, P, Sharma, S, Singh, T.P. | Deposit date: | 2023-02-04 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal structure of the ternary complex of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with Dephosphocoenzyme-A and Phosphonoacetic acid at 2.22 A resolution. To Be Published
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6E8W
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![BU of 6e8w by Molmil](/molmil-images/mine/6e8w) | MPER-TM Domain of HIV-1 envelope glycoprotein (Env) | Descriptor: | Envelope glycoprotein gp160 | Authors: | Fu, Q, Shaik, M.M, Cai, Y, Ghantous, F, Piai, A, Peng, H, Rits-Volloch, S, Liu, Z, Harrison, S.C, Seaman, M.S, Chen, B, Chou, J.J. | Deposit date: | 2018-07-31 | Release date: | 2018-09-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the membrane proximal external region of HIV-1 envelope glycoprotein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1F2L
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6IVY
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![BU of 6ivy by Molmil](/molmil-images/mine/6ivy) | Crystal structure of iron-bound HitA from Pseudomonas aeruginosa | Descriptor: | FE (III) ION, PHOSPHATE ION, Periplasmic Ferric iron-binding Protein HitA | Authors: | Zhang, Z.R, Li, H.Y. | Deposit date: | 2018-12-04 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9999994 Å) | Cite: | Identification and Characterization of a Metalloprotein Involved in Gallium Internalization in Pseudomonas aeruginosa. Acs Infect Dis., 5, 2019
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1BD0
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![BU of 1bd0 by Molmil](/molmil-images/mine/1bd0) | ALANINE RACEMASE COMPLEXED WITH ALANINE PHOSPHONATE | Descriptor: | ALANINE RACEMASE, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID | Authors: | Stamper, G.F, Morollo, A.A, Ringe, D. | Deposit date: | 1998-05-12 | Release date: | 1998-10-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine. Biochemistry, 37, 1998
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4L1X
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![BU of 4l1x by Molmil](/molmil-images/mine/4l1x) | Crystal Structuer of Human 3-alpha Hydroxysteroid Dehydrogenase Type 3 V54L Mutant in Complex with NADP+ and Progesterone | Descriptor: | Aldo-keto reductase family 1 member C2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE, ... | Authors: | Zhang, B, Hu, X.-J, Lin, S.-X. | Deposit date: | 2013-06-03 | Release date: | 2014-04-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human 3-alpha hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20 alpha-HSD activity J.Steroid Biochem.Mol.Biol., 141, 2014
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4XHM
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6OZ4
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8RTH
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![BU of 8rth by Molmil](/molmil-images/mine/8rth) | Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase | Descriptor: | 3-methylcrotonyl-CoA carboxylase, putative, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ... | Authors: | Ruiz, F.M, Plaza-Pegueroles, A, Fernandez-Tornero, C. | Deposit date: | 2024-01-26 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.37 Å) | Cite: | The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function. Structure, 2024
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6OZ2
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4XXW
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6PH2
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![BU of 6ph2 by Molmil](/molmil-images/mine/6ph2) | Complete LOV domain from the LOV-HK sensory protein from Brucella abortus (mutant C69S, construct 15-155) | Descriptor: | Blue-light-activated histidine kinase, FLAVIN MONONUCLEOTIDE | Authors: | Rinaldi, J, Otero, L.H, Fernandez, I, Goldbaum, F.A, Shin, H, Yang, X, Klinke, S. | Deposit date: | 2019-06-25 | Release date: | 2020-12-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
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5OH4
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![BU of 5oh4 by Molmil](/molmil-images/mine/5oh4) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Piperidine-2,6-dione (Glutarimide) | Descriptor: | Cereblon isoform 4, ZINC ION, piperidine-2,6-dione | Authors: | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | Deposit date: | 2017-07-14 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Chemical Ligand Space of Cereblon. Acs Omega, 3, 2018
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6N1K
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5OH2
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![BU of 5oh2 by Molmil](/molmil-images/mine/5oh2) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Pyrrolidin-2-one (Butyrolactam) | Descriptor: | Cereblon isoform 4, ZINC ION, pyrrolidin-2-one | Authors: | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | Deposit date: | 2017-07-14 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Chemical Ligand Space of Cereblon. Acs Omega, 3, 2018
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5OHB
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![BU of 5ohb by Molmil](/molmil-images/mine/5ohb) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Piperidin-2-one (Valerolactam) | Descriptor: | Cereblon isoform 4, ZINC ION, piperidin-2-one | Authors: | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | Deposit date: | 2017-07-14 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Chemical Ligand Space of Cereblon. Acs Omega, 3, 2018
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1FNS
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