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1OL7
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BU of 1ol7 by Molmil
Structure of Human Aurora-A 122-403 phosphorylated on Thr287, Thr288
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SERINE/THREONINE KINASE 6
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1OL5
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Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100, ...
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1OCA
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BU of 1oca by Molmil
HUMAN CYCLOPHILIN A, UNLIGATED, NMR, 20 STRUCTURES
Descriptor: CYCLOPHILIN A
Authors:Ottiger, M, Zerbe, O, Guntert, P, Wuthrich, K.
Deposit date:1997-07-07
Release date:1997-11-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The NMR solution conformation of unligated human cyclophilin A.
J.Mol.Biol., 272, 1997
1PQ9
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HUMAN LXR BETA HORMONE RECEPTOR COMPLEXED WITH T0901317 COMPLEX
Descriptor: 1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL, Oxysterols receptor LXR-beta, benzenesulfonic acid
Authors:Farnegardh, M, Bonn, T, Sun, S, Ljunggren, J, Ahola, H, Wilhelmsson, A, Gustafsson, J.-A, Carlquist, M.
Deposit date:2003-06-18
Release date:2003-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands.
J.Biol.Chem., 278, 2003
1Q02
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BU of 1q02 by Molmil
NMR structure of the UBA domain of p62 (SQSTM1)
Descriptor: sequestosome 1
Authors:Ciani, B, Layfield, R, Cavey, J.R, Sheppard, P.W, Searle, M.S.
Deposit date:2003-07-15
Release date:2003-09-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Ubiquitin-associated Domain of p62 (SQSTM1) and Implications for Mutations That Cause Paget's Disease of Bone
J.Biol.Chem., 278, 2003
1Q2Z
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BU of 1q2z by Molmil
The 3D solution structure of the C-terminal region of Ku86
Descriptor: ATP-dependent DNA helicase II, 80 kDa subunit
Authors:Harris, R, Esposito, D, Sankar, A, Maman, J.D, Hinks, J.A, Pearl, L.H, Driscoll, P.C.
Deposit date:2003-07-28
Release date:2004-01-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The 3D Solution Structure of the C-terminal Region of Ku86 (Ku86CTR)
J.Mol.Biol., 335, 2004
1NFK
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STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER
Descriptor: DNA (5'-D(*TP*GP*GP*GP*AP*AP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB))
Authors:Ghosh, G, Van Duyne, G, Ghosh, S, Sigler, P.B.
Deposit date:1995-02-28
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of NF-kappa B p50 homodimer bound to a kappa B site.
Nature, 373, 1995
1NFB
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BU of 1nfb by Molmil
Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD
Descriptor: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, Inosine-5'-monophosphate dehydrogenase 2, ...
Authors:Risal, D, Strickler, M.D, Goldstein, B.M.
Deposit date:2002-12-13
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Conformation of NAD Bound to Human Inosine Monophosphate Dehydrogenase Type II
To be Published
1PQ6
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HUMAN LXR BETA HORMONE RECEPTOR / GW3965 COMPLEX
Descriptor: ISOPROPYL ALCOHOL, Oxysterols receptor LXR-beta, [3-(3-{[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid
Authors:Farnegardh, M, Bonn, T, Sun, S, Ljunggren, J, Ahola, H, Wilhelmsson, A, Gustafsson, J.-A, Carlquist, M.
Deposit date:2003-06-18
Release date:2003-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands.
J.Biol.Chem., 278, 2003
1PQC
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HUMAN LXR BETA HORMONE RECEPTOR COMPLEXED WITH T0901317
Descriptor: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Oxysterols receptor LXR-beta
Authors:Farnegardh, M, Bonn, T, Sun, S, Ljunggren, J, Ahola, H, Wilhelmsson, A, Gustafsson, J.-A, Carlquist, M.
Deposit date:2003-06-18
Release date:2003-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The three-dimensional structure of the liver X receptor beta reveals a flexible ligand-binding pocket that can accommodate fundamentally different ligands.
J.Biol.Chem., 278, 2003
1NF7
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Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide
Descriptor: Inosine-5'-monophosphate dehydrogenase 2, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ...
Authors:Risal, D, Strickler, M.D, Goldstein, B.M.
Deposit date:2002-12-13
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Inosine Monophosphate Dehydrogenase type II complexed with the MPA/NAD analog C2-MAD
To be Published
1NMK
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BU of 1nmk by Molmil
The Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
Descriptor: (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-DIHYDROXY-3-(3-HYDROXYBEN-ZYL)-18-((E)-3-HYDROXY-1-METHYLPROPENYL)-6-ISOPROPYL-11-METHYL-9-(3-OXO-BUTYL)-19-OXA-1,4,7,25-TETRAAZA-BICYCLO[19.3.1]PENTACOSA-13,15-DIENE-2,5,8,20-TETRAONE, Peptidyl-prolyl cis-trans isomerase A
Authors:Kallen, J, Sedrani, R, Wagner, J.
Deposit date:2003-01-10
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
J.Am.Chem.Soc., 125, 2003
1QBG
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BU of 1qbg by Molmil
CRYSTAL STRUCTURE OF HUMAN DT-DIAPHORASE (NAD(P)H OXIDOREDUCTASE)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1
Authors:Skelly, J.V, Sanderson, M.R, Suter, D.A, Baumann, U, Gregory, D.S, Bennett, M, Hobbs, S.M, Neidle, S.
Deposit date:1999-04-20
Release date:2000-04-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954).
J.Med.Chem., 42, 1999
1Q8G
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BU of 1q8g by Molmil
NMR structure of human Cofilin
Descriptor: Cofilin, non-muscle isoform
Authors:Pope, B.J, Zierler-Gould, K.M, Kuhne, R, Weeds, A.G, Ball, L.J.
Deposit date:2003-08-21
Release date:2004-07-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of human cofilin: rationalizing actin binding and pH sensitivity
J.Biol.Chem., 279, 2004
1QG2
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BU of 1qg2 by Molmil
CANINE GDP-RAN R76E MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1N44
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BU of 1n44 by Molmil
Crystal Structure of Annexin V R23E Mutant
Descriptor: Annexin V, CALCIUM ION, SULFATE ION
Authors:Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A.
Deposit date:2002-10-30
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interfacial basic cluster in anexin V couples phospholipid binding and trimer formation on membrane surfaces
J.Biol.Chem., 278, 2003
1N42
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BU of 1n42 by Molmil
Crystal Structure of Annexin V R149E Mutant
Descriptor: Annexin V, CALCIUM ION, SULFATE ION
Authors:Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A.
Deposit date:2002-10-30
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces
J.Biol.Chem., 278, 2003
1MV0
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BU of 1mv0 by Molmil
NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
Descriptor: Myc box-dependent-interacting protein 1, Myc proto-oncogene protein
Authors:Pineda-Lucena, A, Arrowsmith, C.H.
Deposit date:2002-09-24
Release date:2003-09-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J.Mol.Biol., 351, 2005
1QG4
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BU of 1qg4 by Molmil
CANINE GDP-RAN F72Y MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1Q60
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BU of 1q60 by Molmil
Solution Structure of RSGI RUH-004, a GTF2I domain in Mouse cDNA
Descriptor: General transcription factor II-I
Authors:Doi-Katayama, Y, Hayashi, F, Hirota, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-08-12
Release date:2004-11-23
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-004, a GTF2I domain in Mouse cDNA
To be published
1Q8X
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BU of 1q8x by Molmil
NMR structure of human cofilin
Descriptor: Cofilin, non-muscle isoform
Authors:Pope, B.J, Zierler-Gould, K.M, Kuhne, R, Weeds, A.G, Ball, L.J.
Deposit date:2003-08-22
Release date:2004-07-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of human cofilin: rationalizing actin binding and pH sensitivity
J.Biol.Chem., 279, 2004
1QVY
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BU of 1qvy by Molmil
Crystal structure of RhoGDI K(199,200)R double mutant
Descriptor: Rho GDP-dissociation inhibitor 1, SULFATE ION
Authors:Czepas, J, Devedjiev, Y, Krowarsh, D, Derewenda, U, Derewenda, Z.S.
Deposit date:2003-08-29
Release date:2004-02-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The impact of Lys-->Arg surface mutations on the crystallization of the globular domain of RhoGDI.
Acta Crystallogr.,Sect.D, 60, 2004
1QBK
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STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX
Descriptor: KARYOPHERIN BETA2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Chook, Y.M, Blobel, G.
Deposit date:1999-04-23
Release date:1999-06-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.
Nature, 399, 1999
2CKG
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BU of 2ckg by Molmil
The structure of SENP1 SUMO-2 co-complex suggests a structural basis for discrimination between SUMO paralogues during processing
Descriptor: SENTRIN-SPECIFIC PROTEASE 1
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-04-18
Release date:2006-04-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Structure of Senp1-Sumo-2 Complex Suggests a Structural Basis for Discrimination between Sumo Paralogues During Processing.
Biochem.J., 397, 2006
2IYC
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SENP1 native structure
Descriptor: SENTRIN-SPECIFIC PROTEASE 1
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-14
Release date:2006-08-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Senp1 Native Structure
To be Published

222415

數據於2024-07-10公開中

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