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5YLX
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Integrated illustration of a valid epitope based on the SLA class I structure and tetramer technique could carry forward the development of molecular vaccine in swine species
Descriptor: Beta-2-microglobulin, MHC class I antigen, PRRSV-NSP9-TMP9 peptide
Authors:Pan, X.C, Wei, X.H, Zhang, N, Xia, C.
Deposit date:2017-10-20
Release date:2018-10-24
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Illumination of PRRSV Cytotoxic T Lymphocyte Epitopes by the Three-Dimensional Structure and Peptidome of Swine Lymphocyte Antigen Class I (SLA-I).
Front Immunol, 10, 2019
4WU7
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BU of 4wu7 by Molmil
HLA-A24 in complex with HIV-1 Nef134-8(2F)
Descriptor: 8-Mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Yamagata, A, Fukai, S, Iwamoto, A.
Deposit date:2014-10-31
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Crystal structure of Nef134-8 epitope presented by HLA-A24
To Be Published
3JTT
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BU of 3jtt by Molmil
Cystal structure of Rhesus macaque MHC class I:Mamu-A*02
Descriptor: Beta-2-microglobulin, MHC class I Mamu-A*02, peptide of Protein Nef
Authors:Dai, L, Feng, Y, Qi, J, Gao, G.F.
Deposit date:2009-09-14
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Rhesus macaque MHC class I:Mamu-A*02
To be Published
2IPK
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BU of 2ipk by Molmil
Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2
Descriptor: Enterotoxin type C-3, HA related Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine), ...
Authors:Nguyen, T.T, Stern, L.J.
Deposit date:2006-10-12
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells.
Nat.Chem.Biol., 3, 2007
3J3P
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BU of 3j3p by Molmil
Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy: 135S Poliovirus and C3-Fab Complex
Descriptor: C3 antibody, heavy chain, light chain, ...
Authors:Lin, J, Cheng, N, Hogle, J.M, Steven, A.C, Belnap, D.M.
Deposit date:2013-04-10
Release date:2013-07-03
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy.
J.Immunol., 191, 2013
5WLG
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BU of 5wlg by Molmil
Crystal Structure of H-2Db with the GAP501 peptide (SQL)
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GAP50 peptide, ...
Authors:Gras, S, Farenc, C, Josephs, T, Rossjohn, J.
Deposit date:2017-07-26
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.
Immunity, 47, 2017
4X5X
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BU of 4x5x by Molmil
HLA-DR1 mutant bN82A with covalently linked CLIP106-120(M107W)
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain
Authors:Guenther, S, Freund, C.
Deposit date:2014-12-06
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.199 Å)
Cite:MHC class II complexes sample intermediate states along the peptide exchange pathway.
Nat Commun, 7, 2016
5WJL
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BU of 5wjl by Molmil
Crystal Structure of HLA-A*11:01 with GTS1 peptide
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GTS1 peptide, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-07-23
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
4WWI
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BU of 4wwi by Molmil
Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution
Descriptor: Ig gamma-3 chain C region, Immunoglobulin G-binding protein A
Authors:Deis, L.N, Oas, T.G.
Deposit date:2014-11-11
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:Suppression of conformational heterogeneity at a protein-protein interface.
Proc.Natl.Acad.Sci.USA, 112, 2015
5WMQ
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BU of 5wmq by Molmil
Crystal Structure of HLA-B8 in complex with ELR, an Influenza A virus peptide
Descriptor: Beta-2-microglobulin, ELR peptide from IAV, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-07-31
Release date:2018-06-06
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
4X4M
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BU of 4x4m by Molmil
Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2014-12-03
Release date:2015-04-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.485 Å)
Cite:Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WU5
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BU of 4wu5 by Molmil
HLA-A24 in complex with HIV-1 Nef134-8(wt)
Descriptor: 8-Mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Yamagata, A, Fukai, S, Iwamoto, A.
Deposit date:2014-10-31
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Nef134-8(wt) epitope presented by HLA-A24
To Be Published
5WLI
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BU of 5wli by Molmil
Crystal Structure of H-2Db with the GAP501 peptide (SQL)
Descriptor: Beta-2-microglobulin, GAP50 peptide, H-2 class I histocompatibility antigen, ...
Authors:Gras, S, Farenc, C, Josephs, T, Rossjohn, J.
Deposit date:2017-07-27
Release date:2017-11-15
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.
Immunity, 47, 2017
3J42
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BU of 3j42 by Molmil
Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody
Descriptor: Envelope protein E, Ig heavy chain V region MOPC 21, Igh protein chimera, ...
Authors:Wang, Z, Pennington, J.G, Jiang, W, Rossmann, M.G.
Deposit date:2013-06-13
Release date:2013-07-17
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody.
J.Virol., 87, 2013
5WSH
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BU of 5wsh by Molmil
Structure of HLA-A2 P130
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ...
Authors:Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
5WWI
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BU of 5wwi by Molmil
Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1).
To Be Published
5WXC
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BU of 5wxc by Molmil
Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 2)
Descriptor: Beta-2-microglobulin, H7-25-F, HLA class I histocompatibility antigen, ...
Authors:Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F.
Deposit date:2017-01-07
Release date:2018-01-17
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.
Mbio, 9, 2018
2ICW
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BU of 2icw by Molmil
Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Wang, L, Zhao, Y, Li, H.
Deposit date:2006-09-13
Release date:2007-03-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Nat.Struct.Mol.Biol., 14, 2007
3KYN
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BU of 3kyn by Molmil
Crystal structure of HLA-G presenting KGPPAALTL peptide
Descriptor: Beta-2-microglobulin, CHLORIDE ION, COBALT (II) ION, ...
Authors:Walpole, N.G, Rossjohn, J, Clements, C.S.
Deposit date:2009-12-06
Release date:2010-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide
J.Mol.Biol., 397, 2010
5XOT
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BU of 5xot by Molmil
Crystal structure of pHLA-B35 in complex with TU55 T cell receptor
Descriptor: An HIV reverse transcriptase epitope, Beta-2-microglobulin, GLYCEROL, ...
Authors:Shi, Y, Qi, J, Gao, G.F.
Deposit date:2017-05-31
Release date:2017-06-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.787 Å)
Cite:Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
3JTS
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BU of 3jts by Molmil
GY9-Mamu-A*02-hb2m
Descriptor: Beta-2-microglobulin, MHC class I Mamu-A*02, peptide of Gag-Pol polyprotein
Authors:Dai, L, Feng, Y, Qi, J, Gao, G.F.
Deposit date:2009-09-14
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structure of Mamu A*2
To be Published
5YXU
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BU of 5yxu by Molmil
an affinity enhanced T cell receptor in complex with HLA-A0201 restricted HCV NS3 peptide KLVALGINAV
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Yi, L.
Deposit date:2017-12-07
Release date:2018-12-12
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:an affinity enhanced T cell receptor in complex with HLA-A0201 restricted HCV NS3 peptide KLVALGINAV
To Be Published
4YPG
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BU of 4ypg by Molmil
Structural Insights Into the Neutralization Properties of a Human Anti-Interferon Monoclonal Antibody
Descriptor: Interferon alpha-2, NICKEL (II) ION, Sifalimumab heavy chain, ...
Authors:Oganesyan, V, Dall'Acqua, W.F.
Deposit date:2015-03-12
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab.
J.Biol.Chem., 290, 2015
2IAM
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BU of 2iam by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
3HPJ
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BU of 3hpj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-06-04
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010

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數據於2024-07-17公開中

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