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8IKE
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BU of 8ike by Molmil
Transcription factors LMX1a mutant-R199A homeobox domain complex with Wnt1 promoter
Descriptor: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), LMX1A factor
Authors:Lv, M.Q, Lin, L.Q.
Deposit date:2023-02-28
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
5LJB
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BU of 5ljb by Molmil
Crystal structure of holo human CRBP1
Descriptor: RETINOL, Retinol-binding protein 1
Authors:zanotti, G, Valese, F, Berni, R, menozzi, I.
Deposit date:2016-07-18
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.263 Å)
Cite:Structural and molecular determinants affecting the interaction of retinol with human CRBP1.
J. Struct. Biol., 197, 2017
5LUM
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BU of 5lum by Molmil
Alpha-crystallin domain of human HSPB6 patched with its N-terminal peptide
Descriptor: Heat shock protein beta-6, SULFATE ION
Authors:Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V.
Deposit date:2016-09-09
Release date:2017-02-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
Structure, 25, 2017
5LJG
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BU of 5ljg by Molmil
Crystal structure of holo human CRBP1
Descriptor: PALMITIC ACID, Retinol-binding protein 1
Authors:Zanotti, G, Vallese, F, Berni, R, Menozzi, I.
Deposit date:2016-07-18
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.146 Å)
Cite:Structural and molecular determinants affecting the interaction of retinol with human CRBP1.
J. Struct. Biol., 197, 2017
8IEI
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BU of 8iei by Molmil
Cryo-EM structure of GPR156A/B of G-protein free GPR156 (local refine)
Descriptor: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
5LKF
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BU of 5lkf by Molmil
Bovine beta-lactoglobulin complex with myristic acid at high pressure (0.55 GPa)
Descriptor: Beta-lactoglobulin, MYRISTIC ACID
Authors:Kurpiewska, K, Lewinski, K, Garbacz, K.
Deposit date:2016-07-22
Release date:2016-08-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Towards understanding the effect of high pressure on food protein allergenicity: beta-lactoglobulin structural studies.
Food Chem, 270, 2019
8IEQ
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BU of 8ieq by Molmil
Cryo-EM structure of G-protein free GPR156
Descriptor: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
Authors:Shin, J, Park, J, Cho, Y.
Deposit date:2023-02-15
Release date:2024-02-14
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
8IK5
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BU of 8ik5 by Molmil
Transcription factor LMX1a homeobox domain in complex with Wnt1 promoter
Descriptor: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), GLYCEROL, ...
Authors:Lv, M.Q, Lin, L.Q.
Deposit date:2023-02-28
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.989 Å)
Cite:Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
8ILW
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BU of 8ilw by Molmil
Transcription factor LMX1a homeobox domain in complex with Pitx3 promoter
Descriptor: DNA (5'-D(*CP*AP*AP*CP*AP*CP*TP*TP*AP*AP*TP*CP*CP*AP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*GP*AP*TP*TP*AP*AP*GP*TP*GP*TP*T)-3'), LMX1A factor
Authors:Lv, M.Q, Lin, L.Q.
Deposit date:2023-03-04
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain
Febs J., 2024
8IMW
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BU of 8imw by Molmil
Crystal structure of response regulator PmrA receiver domain
Descriptor: Transcriptional regulator
Authors:Ouyang, Z, Wen, Y.
Deposit date:2023-03-07
Release date:2024-03-13
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanistic and biophysical characterization of polymyxin resistance response regulator PmrA in Acinetobacter baumannii.
Front Microbiol, 15, 2024
7EZE
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BU of 7eze by Molmil
Thorarchaeota Rab GTP-gamma-S/Mg2+ (soak)
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Thorarchaeota Rab
Authors:Robinson, R.C, Tran, L.T.
Deposit date:2021-06-01
Release date:2022-06-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Thor-Rab
To Be Published
7EZB
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BU of 7ezb by Molmil
Thorarchaeota Rab bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Thorarchaeota Rab
Authors:Robinson, R.C, Tran, L.T.
Deposit date:2021-06-01
Release date:2022-06-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of Thor-Rab
To Be Published
7EZD
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BU of 7ezd by Molmil
Thorarchaeota Rab co-crystallized with GTP gamma-S
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Chains: A,B, GUANOSINE-5'-DIPHOSPHATE
Authors:Robinson, R.C, Tran, L.T.
Deposit date:2021-06-01
Release date:2022-06-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of Thor-Rab
To Be Published
5LIV
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BU of 5liv by Molmil
Crystal structure of myxobacterial CYP260A1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cytochrome P450 CYP260A1,Cytochrome P450 CYP260A1, DIMETHYL SULFOXIDE, ...
Authors:Carius, Y, Khatri, Y, Bernhardt, R, Lancaster, C.R.D.
Deposit date:2016-07-15
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural characterization of CYP260A1 from Sorangium cellulosum to investigate the 1 alpha-hydroxylation of a mineralocorticoid.
FEBS Lett., 590, 2016
7FIC
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BU of 7fic by Molmil
Reversible lysine-targeted probes reveal residence time-based kinase selectivity in vivo
Descriptor: 6-[(5-cyclopropyl-1~{H}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{N}-prop-2-ynyl-pyrimidine-4-carboxamide, Aurora kinase A, CHLORIDE ION
Authors:Craven, G.B, Wan, X.B, Taunton, J.
Deposit date:2021-07-31
Release date:2022-06-08
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Reversible lysine-targeted probes reveal residence time-based kinase selectivity.
Nat.Chem.Biol., 18, 2022
5LIS
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BU of 5lis by Molmil
Insulin solved by Native SAD from a dataset collected in one second
Descriptor: Insulin
Authors:Casanas, A, Finke, A, Wang, M.
Deposit date:2016-07-15
Release date:2016-08-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:EIGER detector: application in macromolecular crystallography.
Acta Crystallogr D Struct Biol, 72, 2016
5LJ9
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BU of 5lj9 by Molmil
Structure of the E. coli MacB ABC domain (C2221)
Descriptor: Macrolide export ATP-binding/permease protein MacB
Authors:Crow, A.
Deposit date:2016-07-18
Release date:2017-11-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LK9
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BU of 5lk9 by Molmil
Dehaloperoxidase B from Amphitrite ornata: indazole complex
Descriptor: 1H-indazole, Dehaloperoxidase B, GLYCEROL, ...
Authors:Chicano, T.M, Dworkowski, F.S.N, Hough, M.A.
Deposit date:2016-07-21
Release date:2017-08-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Dehaloperoxidase B from Amphitrite ornata: indazole complex
to be published
5M0N
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BU of 5m0n by Molmil
Crystal structure of cytochrome P450 OleT in complex with formate
Descriptor: FORMIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Tee, K.L, Munro, A, Matthews, S, Leys, D, Levy, C.
Deposit date:2016-10-05
Release date:2017-01-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE.
J. Biol. Chem., 292, 2017
7F68
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BU of 7f68 by Molmil
Crystal structure of N-ras S89D
Descriptor: GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Li, Y, Sun, Q.
Deposit date:2021-06-24
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal structure of N-ras S89D
To Be Published
7F4Z
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BU of 7f4z by Molmil
X-ray crystal structure of Y149A mutated Hsp72-NBD in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Heat shock 70 kDa protein 1B, ...
Authors:Yokoyama, T, Fujii, S, Nabeshima, Y, Mizuguchi, M.
Deposit date:2021-06-21
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP.
Iucrj, 9, 2022
7F4X
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BU of 7f4x by Molmil
Joint neutron and X-ray crystal structure of the nucleotide-binding domain of Hsp72 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1B, MAGNESIUM ION, ...
Authors:Yokoyama, T, Ostermann, A, Schrader, T.E.
Deposit date:2021-06-21
Release date:2022-06-29
Last modified:2024-04-03
Method:NEUTRON DIFFRACTION (1.6 Å), X-RAY DIFFRACTION
Cite:Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP.
Iucrj, 9, 2022
7F50
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BU of 7f50 by Molmil
X-ray crystal structure of Y149A mutated Hsp72-NBD in complex with AMPPnP
Descriptor: CHLORIDE ION, Heat shock 70 kDa protein 1B, MAGNESIUM ION, ...
Authors:Yokoyama, T, Fujii, S, Nabeshima, Y, Mizuguchi, M.
Deposit date:2021-06-21
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP.
Iucrj, 9, 2022
7F2X
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BU of 7f2x by Molmil
Crystal structure of MEK1 C121S mutant
Descriptor: MEK1 F11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Fujioka, Y, Noda, N.N.
Deposit date:2021-06-15
Release date:2022-06-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nat Commun, 13, 2022
5LHS
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BU of 5lhs by Molmil
The ligand free catalytic domain of murine urokinase-type plasminogen activator
Descriptor: NICKEL (II) ION, SULFATE ION, Urokinase-type plasminogen activator
Authors:Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P.J, Andreasen, P.A.
Deposit date:2016-07-12
Release date:2017-06-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.047 Å)
Cite:Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Sci Rep, 7, 2017

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數據於2024-10-16公開中

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