PDB: 8880 resultsInfo pagesStatus searchChemie searchBIRD

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7U75	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 90s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7E	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 60s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.58 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7F	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 90s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.65 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7Z	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.12 mM Mn2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.67 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U80	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.25 mM Mn2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.83 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U74	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 30s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.52 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7I	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 180s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.57 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U81	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.5 mM Mn2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7K	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 600s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.67 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
6Q4T	KOD DNA pol in a closed ternary complex with 7-deaza-7-(2-(2-hydroxyethoxy)-N-(prop-2-yn-1-yl)acetamide)-2-dATP Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), DNA (5'-D(P*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... Authors: Kropp, H.M, Diederichs, K, Marx, A. Deposit date: 2018-12-06 Release date: 2019-02-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.997 Å) Cite: The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide. Angew.Chem.Int.Ed.Engl., 58, 2019
3FWB	Sac3:Sus1:Cdc31 complex Descriptor: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1 Authors: Stewart, M, Jani, D. Deposit date: 2009-01-17 Release date: 2009-04-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol.Cell, 33, 2009
3FWC	Sac3:Sus1:Cdc31 complex Descriptor: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1, ... Authors: Stewart, M, Jani, D. Deposit date: 2009-01-17 Release date: 2009-04-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol.Cell, 33, 2009
3SI8	Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2) Descriptor: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ... Authors: Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W. Deposit date: 2011-06-17 Release date: 2011-08-03 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structure and mechanism of human DNA polymerase eta. Nature, 465, 2010
4TUS	Human DNA polymerase beta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2) WITH MANGANESE IN THE ACTIVE SITE. Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ... Authors: Koag, M.C, Lee, S. Deposit date: 2014-06-24 Release date: 2014-10-01 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta. J.Biol.Chem., 289, 2014
3V7E	Crystal structure of YbxF bound to the SAM-I riboswitch aptamer Descriptor: COBALT HEXAMMINE(III), MAGNESIUM ION, Ribosome-associated protein L7Ae-like, ... Authors: Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. Deposit date: 2011-12-21 Release date: 2012-03-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops. Rna, 18, 2012
6HV9	S. cerevisiae CMG-Pol epsilon-DNA Descriptor: Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ... Authors: Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A. Deposit date: 2018-10-10 Release date: 2018-12-12 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (4.98 Å) Cite: Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome. Nat Commun, 9, 2018
5TB8	Precatalytic ternary complex of Human DNA Polymerase Beta in closed conformation With Gapped DNA substrate incoming (-)3TC-TP and Mn2+. Descriptor: 10- MER PRIMER, 16- MER TEMPLATE, 5-MER PHOSPHORYLATED DOWNSTREAM PRIME, ... Authors: Vyas, R, Suo, Z. Deposit date: 2016-09-11 Release date: 2017-01-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase. J. Am. Chem. Soc., 139, 2017
6UOM	Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP Descriptor: 1,2-ETHANEDIOL, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Smith, M.R, Freudenthal, B.D. Deposit date: 2019-10-15 Release date: 2020-01-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
6AR5	Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (Duplex Only) Descriptor: DNA, RNA Authors: Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. Deposit date: 2017-08-21 Release date: 2017-11-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.413 Å) Cite: Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Mol. Cell, 68, 2017
5TB9	Precatalytic ternary complex of Human DNA Polymerase Beta in closed conformation With Gapped DNA substrate incoming (-)FTC-TP and Mn2+. Descriptor: 10- MER PRIMER, 16- MER TEMPLATE, 5-MER PHOSPHORYLATED DOWNSTREAM PRIMER, ... Authors: Vyas, R, Suo, Z. Deposit date: 2016-09-11 Release date: 2017-01-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase. J. Am. Chem. Soc., 139, 2017
5TBB	Postcatalytic ternary complex of Human DNA Polymerase Beta with Gapped DNA substrate, incorporated (-)FTC and PPi. Descriptor: 10- MER PRIMER, 16- MER TEMPLATE, 5-MER PHOSPHORYLATED DOWNSTREAM PRIMER, ... Authors: Vyas, R, Suo, Z. Deposit date: 2016-09-11 Release date: 2017-01-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase. J. Am. Chem. Soc., 139, 2017
7ICJ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CUCL2 (0.1 MILLIMOLAR) Descriptor: COPPER (II) ION, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-04-19 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.5 Å) Cite: A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
6Q4U	KlenTaq DNA pol in a closed ternary complex with 7-deaza-7-(2-(2-hydroxyethoxy)-N-(prop-2-yn-1-yl)acetamide)-2-dATP Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*(DOC))-3'), ... Authors: Kropp, H.M, Diederichs, K, Marx, A. Deposit date: 2018-12-06 Release date: 2019-02-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.005 Å) Cite: The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide. Angew.Chem.Int.Ed.Engl., 58, 2019
3HW6	Crystal structure of avian influenza virus PA_N in complex with Mn Descriptor: MANGANESE (II) ION, Polymerase acidic protein Authors: Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z. Deposit date: 2009-06-17 Release date: 2009-10-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
6Q4V	KlenTaq DNA polymerase in complex with dATP Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... Authors: Kropp, H.M, Diederichs, K, Marx, A. Deposit date: 2018-12-06 Release date: 2019-02-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.006 Å) Cite: The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide. Angew.Chem.Int.Ed.Engl., 58, 2019

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