6JQ2
| Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide | Descriptor: | Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... | Authors: | Bai, P, Yin, L. | Deposit date: | 2019-03-28 | Release date: | 2020-04-01 | Last modified: | 2021-02-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
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1A4K
| DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | Descriptor: | ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | Authors: | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | Deposit date: | 1998-01-30 | Release date: | 1998-05-13 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science, 279, 1998
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3WEX
| Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen | Authors: | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-16 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5 J. Mol. Biol., 426, 2014
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2YPL
| Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms | Descriptor: | AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ... | Authors: | Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M. | Deposit date: | 2012-10-30 | Release date: | 2012-11-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms. Proc.Natl.Acad.Sci.USA, 109, 2012
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3S4S
| Crystal structure of CD4 mutant bound to HLA-DR1 | Descriptor: | GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Li, Y. | Deposit date: | 2011-05-20 | Release date: | 2011-09-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
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5JWE
| Crystal structure of H-2Db in complex with the LCMV-derived GP92-101 peptide | Descriptor: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | Authors: | Buratto, J, Badia-Martinez, D, Norstrom, M, Sandalova, T, Achour, A. | Deposit date: | 2016-05-12 | Release date: | 2017-05-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity. PLoS ONE, 12, 2017
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5C9J
| Human CD1c with ligands in A' and F' channel | Descriptor: | Beta-2-microglobulin, GLYCEROL, LAURIC ACID, ... | Authors: | Tews, I, Machelett, M.M, Mansour, S, Gadola, S.D. | Deposit date: | 2015-06-27 | Release date: | 2016-03-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells. Proc.Natl.Acad.Sci.USA, 113, 2016
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1S7W
| Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 index peptide and three of its escape variants | Descriptor: | Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ... | Authors: | Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A. | Deposit date: | 2004-01-30 | Release date: | 2004-05-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J.Immunol., 172, 2004
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5MZM
| Structure of H-2Db in complex with TEIPP APL Trh4 p3P | Descriptor: | Beta-2-microglobulin, Ceramide synthase 5 derived peptide Trh4 p3P, GLYCEROL, ... | Authors: | Hafstrand, I, Achour, A, Sandalova, T. | Deposit date: | 2017-02-01 | Release date: | 2018-03-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability. J. Immunol., 200, 2018
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7LG2
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6CQL
| Crystal structure of F24 TCR -DR11-RQ13 peptide complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F24 alpha chain, F24 beta Chain, ... | Authors: | Farenc, C, Gras, S, Rossjohn, J. | Deposit date: | 2018-03-15 | Release date: | 2018-06-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CD4+T cell-mediated HLA class II cross-restriction in HIV controllers. Sci Immunol, 3, 2018
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4LCW
| The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH | Descriptor: | 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Patel, O, Rossjohn, J. | Deposit date: | 2013-06-24 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J.Exp.Med., 210, 2013
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1I3R
| CRYSTAL STRUCTURE OF A MUTANT IEK CLASS II MHC MOLECULE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FUSION PROTEIN CONSISTING OF MHC E-BETA-K PRECURSOR, ... | Authors: | Kappler, J.W, Wilson, N. | Deposit date: | 2001-02-15 | Release date: | 2001-06-20 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mutations changing the kinetics of class II MHC peptide exchange. Immunity, 14, 2001
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1C5D
| THE CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF A RAT MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR | Descriptor: | MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR | Authors: | Kontou, M, Leonidas, D.D, Vatzaki, E.H, Tsantili, P, Mamalaki, A, Oikonomakos, N.G, Acharya, K.R, Tzartos, S.J. | Deposit date: | 1999-11-17 | Release date: | 1999-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor. Eur.J.Biochem., 267, 2000
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1KTD
| CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ... | Authors: | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | Deposit date: | 2002-01-15 | Release date: | 2002-05-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
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8DV4
| Crystal structure of the BC8B TCR-CD1b-PI complex | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Farquhar, R, Rossjohn, J, Shahine, A. | Deposit date: | 2022-07-28 | Release date: | 2023-04-19 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | alpha beta T-cell receptor recognition of self-phosphatidylinositol presented by CD1b. J.Biol.Chem., 299, 2023
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3RWE
| rhesus macaque MHC class I molecule Mamu-B*17-FW9 | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Major histocompatibility complex class I, ... | Authors: | Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F. | Deposit date: | 2011-05-09 | Release date: | 2012-03-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus J.Immunol., 187, 2011
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2NTS
| Crystal Structure of SEK-hVb5.1 | Descriptor: | Staphylococcal enterotoxin K, TRBC1 protein | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | Deposit date: | 2006-11-08 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site J.Mol.Biol., 371, 2007
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1JK8
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6CPO
| Crystal structure of DR15 presenting the RQ13 peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Farenc, C, Gras, S, Rossjohn, J. | Deposit date: | 2018-03-13 | Release date: | 2018-06-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CD4+T cell-mediated HLA class II cross-restriction in HIV controllers. Sci Immunol, 3, 2018
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6CHF
| Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uncharacterized protein DKFZp686C11235 | Authors: | Gohain, N, Tolbert, W.D, Pazgier, M. | Deposit date: | 2018-02-22 | Release date: | 2019-02-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding. Structure, 2020
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1NGQ
| N1G9 (IGG1-LAMBDA) FAB FRAGMENT | Descriptor: | N1G9 (IGG1-LAMBDA), SULFATE ION | Authors: | Mizutani, R, Satow, Y. | Deposit date: | 1995-06-23 | Release date: | 1996-07-11 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate. J.Mol.Biol., 254, 1995
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4WU5
| HLA-A24 in complex with HIV-1 Nef134-8(wt) | Descriptor: | 8-Mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shimizu, A, Yamagata, A, Fukai, S, Iwamoto, A. | Deposit date: | 2014-10-31 | Release date: | 2015-05-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Nef134-8(wt) epitope presented by HLA-A24 To Be Published
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1KLG
| Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | Deposit date: | 2001-12-11 | Release date: | 2002-08-02 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line. J.Mol.Biol., 319, 2002
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1NGP
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