7ULR
| recombinant kappa-bungarotoxin | Descriptor: | Kappa-bungarotoxin | Authors: | Xu, J, Lei, X, Chen, L. | Deposit date: | 2022-04-05 | Release date: | 2023-05-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of recombinant kappa-bungarotoxin at 1.8 Angstroms resolution. To Be Published
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2NBT
| NEURONAL BUNGAROTOXIN, NMR, 10 STRUCTURES | Descriptor: | NEURONAL BUNGAROTOXIN | Authors: | Oswald, R.E, Sutcliffe, M.J, Bamberger, M, Loring, R.H, Braswell, E, Dobson, C.M. | Deposit date: | 1997-10-29 | Release date: | 1998-03-11 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of neuronal bungarotoxin determined by two-dimensional NMR spectroscopy: calculation of tertiary structure using systematic homologous model building, dynamical simulated annealing, and restrained molecular dynamics. Biochemistry, 31, 1992
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2MIX
| Structure of a novel venom peptide toxin from sample limited terebrid marine snail | Descriptor: | venom peptide toxin | Authors: | Bhuiyan, M.H, Anand, P, Grigoryan, A, Holford, M, Poget, S.F. | Deposit date: | 2013-12-20 | Release date: | 2014-12-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Sample limited characterization of a novel disulfide-rich venom peptide toxin from terebrid marine snail Terebra variegata. Plos One, 9, 2014
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8D9Y
| Crystal structure of Taipan alpha-neurotoxin in complex with Centi-3FTX-D09 antibody | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Centi-3FTX-D09 Fab heavy chain, ... | Authors: | Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D. | Deposit date: | 2022-06-12 | Release date: | 2023-06-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Venom protection by antibody from a snakebite hyperimmune subject To Be Published
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8D9Z
| Crystal structure of Cobra alpha-neurotoxin in complex with Centi-3FTX-D09 antibody | Descriptor: | ACETATE ION, Centi-3FTX-D09 Fab heavy chain, Centi-3FTX-D09 Fab light chain, ... | Authors: | Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D. | Deposit date: | 2022-06-12 | Release date: | 2023-06-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Venom protection by antibody from a snakebite hyperimmune subject To Be Published
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8DA1
| Crystal structure of Krait alpha-neurotoxin in complex with Centi-3FTX-D09 antibody | Descriptor: | Alpha-bungarotoxin, Centi-3FTX-D09 Fab heavy chain, Centi-3FTX-D09 Fab light chain | Authors: | Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D. | Deposit date: | 2022-06-12 | Release date: | 2023-06-14 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Venom protection by antibody from a snakebite hyperimmune subject To Be Published
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8DA0
| Crystal structure of Mamba alpha-neurotoxin in complex with Centi-3FTX-D09 antibody | Descriptor: | ACETATE ION, Alpha-elapitoxin-Dpp2d, Centi-3FTX-D09 Fab heavy chain, ... | Authors: | Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D. | Deposit date: | 2022-06-12 | Release date: | 2023-06-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Venom protection by antibody from a snakebite hyperimmune subject To Be Published
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6LCY
| Crystal structure of Synaptotagmin-7 C2B in complex with IP6 | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7 | Authors: | Zhang, Y, Zhang, X, Rao, F, Wang, C. | Deposit date: | 2019-11-20 | Release date: | 2021-03-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis. Nat Metab, 3, 2021
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1MXN
| Solution structure of alpha-conotoxin AuIB | Descriptor: | alpha-conotoxin AuIB | Authors: | Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J. | Deposit date: | 2002-10-02 | Release date: | 2002-12-30 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity. J.Biol.Chem., 277, 2002
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1MXP
| Solution structure of the ribbon disulfide bond isomer of alpha-conotoxin AuIB | Descriptor: | alpha-conotoxin AuIB | Authors: | Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J. | Deposit date: | 2002-10-03 | Release date: | 2002-12-30 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity. J.Biol.Chem., 277, 2002
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2MJ1
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8F04
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2LER
| Conotoxin pc16a | Descriptor: | Conotoxin pc16a | Authors: | Dyubankova, N, Lescrinier, E, Van Der Haegen, A, Peigneur, S, Tytgat, J. | Deposit date: | 2011-06-22 | Release date: | 2012-04-11 | Last modified: | 2012-04-18 | Method: | SOLUTION NMR | Cite: | Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity. Peptides, 34, 2012
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2MXM
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7EDK
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2YKL
| Structure of human anti-nicotine Fab fragment in complex with nicotine-11-yl-methyl-(4-ethylamino-4-oxo)-butanoate | Descriptor: | FAB FRAGMENT, HEAVY CHAIN, LIGHT CHAIN, ... | Authors: | Tars, K, Kotelovica, S, Lipowsky, G, Bauer, M, Beerli, R, Bachmann, M, Maurer, P. | Deposit date: | 2011-05-27 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Different Binding Modes of Free and Carrier-Protein-Coupled Nicotine in a Human Monoclonal Antibody. J.Mol.Biol., 415, 2012
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2YK1
| Structure of human anti-nicotine Fab fragment in complex with nicotine | Descriptor: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, FAB FRAGMENT, HEAVY CHAIN, ... | Authors: | Tars, K, Kotelovica, S, Lipowsky, G, Bauer, M, Beerli, R, Bachmann, M, Maurer, P. | Deposit date: | 2011-05-25 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Different Binding Modes of Free and Carrier-Protein-Coupled Nicotine in a Human Monoclonal Antibody. J.Mol.Biol., 415, 2012
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3E37
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2IQY
| Rat Phosphatidylethanolamine-Binding Protein | Descriptor: | CALCIUM ION, CHLORIDE ION, Phosphatidylethanolamine-binding protein 1 | Authors: | Kim, Y, Joachimiak, G, Heil, G.L, Koide, S, Joachimiak, A. | Deposit date: | 2006-10-14 | Release date: | 2007-09-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of Rat Phosphatidylethanolamine-Binding Protein To be Published
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3E32
| Protein farnesyltransferase complexed with FPP and ethylenediamine scaffold inhibitor 2 | Descriptor: | FARNESYL DIPHOSPHATE, N-benzyl-N-(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-1H-imidazole-4-sulfonamide, Protein farnesyltransferase subunit beta, ... | Authors: | Hast, M.A, Beese, L.S. | Deposit date: | 2008-08-06 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem.Biol., 16, 2009
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3EUV
| Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10, W102T, Y154T) in complex with BiotinGPP | Descriptor: | (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ... | Authors: | Guo, Z, Nguyen, U.T.T, Delon, C, Bon, R.S, Blankenfeldt, W, Goody, R.S, Waldmann, H, Wolters, D, Alexandrov, K. | Deposit date: | 2008-10-11 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Analysis of the eukaryotic prenylome by isoprenoid affinity tagging Nat.Chem.Biol., 5, 2009
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3E34
| Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10 | Descriptor: | 3-{2'-[{[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl}(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)sulfamoyl]biphenyl-3-yl}propanoic acid, FARNESYL DIPHOSPHATE, Protein farnesyltransferase subunit beta, ... | Authors: | Hast, M.A, Beese, L.S. | Deposit date: | 2008-08-06 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem.Biol., 16, 2009
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3E30
| Protein farnesyltransferase complexed with FPP and ethylene diamine inhibitor 4 | Descriptor: | FARNESYL DIPHOSPHATE, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ... | Authors: | Hast, M.A, Beese, L.S. | Deposit date: | 2008-08-06 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem.Biol., 16, 2009
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3EU5
| Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BiotinGPP | Descriptor: | (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ... | Authors: | Guo, Z, Nguyen, U.T.T, Delon, C, Bon, R.S, Blankenfeldt, W, Goody, R.S, Waldmann, H, Wolters, D, Alexandrov, K. | Deposit date: | 2008-10-09 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analysis of the eukaryotic prenylome by isoprenoid affinity tagging Nat.Chem.Biol., 5, 2009
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1TN6
| Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A Resolution | Descriptor: | ACETIC ACID, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ... | Authors: | Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S. | Deposit date: | 2004-06-11 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity J.Mol.Biol., 343, 2004
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