2L31
 
 | | Human PARP-1 zinc finger 2 | | Descriptor: | Poly [ADP-ribose] polymerase 1, ZINC ION | | Authors: | Neuhaus, D, Eustermann, S, Yang, J, Videler, H. | | Deposit date: | 2010-08-30 | | Release date: | 2011-02-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
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2L30
 | | Human PARP-1 zinc finger 1 | | Descriptor: | Poly [ADP-ribose] polymerase 1, ZINC ION | | Authors: | Neuhaus, D, Eustermann, S, Yang, J, Videler, H. | | Deposit date: | 2010-08-30 | | Release date: | 2011-02-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger.
J.Mol.Biol., 407, 2011
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2JVY
 | | Solution Structure of the EDA-ID-related C417F mutant of human NEMO zinc finger | | Descriptor: | NF-kappa-B essential modulator, ZINC ION | | Authors: | Cordier, F, Vinolo, E, Veron, M, Delepierre, M, Agou, F. | | Deposit date: | 2007-09-28 | | Release date: | 2008-03-18 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.
J.Mol.Biol., 377, 2008
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2K9H
 | | The hantavirus glycoprotein G1 tail contains a dual CCHC-type classical zinc fingers | | Descriptor: | Glycoprotein, ZINC ION | | Authors: | Estrada, D.F, Boudreaux, D.M, Zhong, D, St Jeor, S.C, De Guzman, R.N. | | Deposit date: | 2008-10-13 | | Release date: | 2009-01-27 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The Hantavirus Glycoprotein G1 Tail Contains Dual CCHC-type Classical Zinc Fingers.
J.Biol.Chem., 284, 2009
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2I5O
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2JVX
 | | Solution Structure of human NEMO zinc finger | | Descriptor: | NF-kappa-B essential modulator, ZINC ION | | Authors: | Cordier, F, Vinolo, E, Veron, M, Delepierre, M, Agou, F. | | Deposit date: | 2007-09-28 | | Release date: | 2008-03-18 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.
J.Mol.Biol., 377, 2008
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2KO0
 | | Solution structure of the THAP zinc finger of THAP1 in complex with its DNA target | | Descriptor: | RRM1, THAP domain-containing protein 1, ZINC ION | | Authors: | Campagne, S, Gervais, V, Saurel, O, Milon, A. | | Deposit date: | 2009-09-08 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural determinants of specific DNA-recognition by the THAP zinc finger
Nucleic Acids Res., 2010
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2JOX
 | | Embryonic Neural Inducing Factor Churchill is not a DNA-Binding Zinc Finger Protein: Solution Structure Reveals a Solvent-Exposed beta-Sheet and Zinc Binuclear Cluster | | Descriptor: | Churchill protein, ZINC ION | | Authors: | Lee, B.M, Buck-Koehntop, B.A, Martinez-Yamout, M.A, Gottesfeld, J.M, Dyson, H, Wright, P.E. | | Deposit date: | 2007-04-07 | | Release date: | 2007-08-21 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Embryonic Neural Inducing Factor Churchill Is not a DNA-binding Zinc Finger Protein: Solution Structure Reveals a Solvent-exposed beta-Sheet and Zinc Binuclear Cluster
J.Mol.Biol., 371, 2007
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2NAX
 | | Structure of CCHC zinc finger domain of Pcf11 | | Descriptor: | Protein PCF11, ZINC ION | | Authors: | Yang, F, Varani, G. | | Deposit date: | 2016-01-12 | | Release date: | 2016-11-23 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The C terminus of Pcf11 forms a novel zinc-finger structure that plays an essential role in mRNA 3'-end processing.
RNA, 23, 2017
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2KDP
 | | Solution Structure of the SAP30 zinc finger motif | | Descriptor: | Histone deacetylase complex subunit SAP30, ZINC ION | | Authors: | He, Y, Imhoff, R, Sahu, A, Radhakrishnan, I. | | Deposit date: | 2009-01-14 | | Release date: | 2009-03-17 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a novel zinc finger motif in the SAP30 polypeptide of the Sin3 corepressor complex and its potential role in nucleic acid recognition
Nucleic Acids Res., 37, 2009
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2MRF
 | | NMR structure of the ubiquitin-binding zinc finger (UBZ) domain from human Rad18 | | Descriptor: | E3 ubiquitin-protein ligase RAD18, ZINC ION | | Authors: | Rizzo, A.A, Salerno, P.E, Bezsonova, I, Korzhnev, D.M. | | Deposit date: | 2014-07-03 | | Release date: | 2014-10-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response.
Biochemistry, 53, 2014
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2C6A
 | | Solution structure of the C4 zinc-finger domain of HDM2 | | Descriptor: | UBIQUITIN-PROTEIN LIGASE E3 MDM2, ZINC ION | | Authors: | Yu, G.W, Allen, M.D, Andreeva, A, Fersht, A.R, Bycroft, M. | | Deposit date: | 2005-11-08 | | Release date: | 2006-01-04 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the C4 Zinc Finger Domain of Hdm2.
Protein Sci., 15, 2006
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2C6B
 | | Solution structure of the C4 zinc-finger domain of HDM2 | | Descriptor: | UBIQUITIN-PROTEIN LIGASE E3 MDM2, ZINC ION | | Authors: | Yu, G.W, Allen, M.D, Andreeva, A, Fersht, A.R, Bycroft, M. | | Deposit date: | 2005-11-08 | | Release date: | 2006-01-04 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the C4 Zinc Finger Domain of Hdm2.
Protein Sci., 15, 2006
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2BAI
 | | The Zinc finger domain of Mengovirus Leader polypeptide | | Descriptor: | Genome polyprotein, ZINC ION | | Authors: | Cornilescu, C.C, Porter, F.W, Qin, Z, Lee, M.S, Palmenberg, A.C, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-10-14 | | Release date: | 2006-01-24 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the mengovirus Leader protein zinc-finger domain.
Febs Lett., 582, 2008
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1F2I
 | | COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA | | Descriptor: | 5'-D(*AP*TP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*AP*T)-3', FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12, ZINC ION | | Authors: | Wang, B.S, Grant, R.A, Pabo, C.O. | | Deposit date: | 2000-05-25 | | Release date: | 2001-09-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA.
Nat.Struct.Biol., 8, 2001
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1N0Z
 | | Solution structure of the first zinc-finger domain from ZNF265 | | Descriptor: | ZINC ION, ZNF265 | | Authors: | Plambeck, C.A, Fairley, K, Kwan, A.H.Y, Westman, B.J, Adams, D, Morris, B, Mackay, J.P. | | Deposit date: | 2002-10-15 | | Release date: | 2003-07-22 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The structure of the zinc finger domain from human splicing factor ZNF265 fold
J.BIOL.CHEM., 278, 2003
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6DF8
 | | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS), pH 6.5 | | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | Authors: | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | Deposit date: | 2018-05-14 | | Release date: | 2019-05-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.536 Å) | | Cite: | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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6DF5
 | | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) | | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | Authors: | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | Deposit date: | 2018-05-14 | | Release date: | 2019-05-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.819 Å) | | Cite: | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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6DFB
 | | Kaiso (ZBTB33) K539A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) | | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | Authors: | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | Deposit date: | 2018-05-14 | | Release date: | 2019-05-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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6DFC
 | | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) with a T-to-U substitution | | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*AP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*UP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | Authors: | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | Deposit date: | 2018-05-14 | | Release date: | 2019-05-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
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4F6N
 | | Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA | | Descriptor: | DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ... | | Authors: | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | | Deposit date: | 2012-05-15 | | Release date: | 2012-09-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4F6M
 | | Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA | | Descriptor: | DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ... | | Authors: | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | | Deposit date: | 2012-05-15 | | Release date: | 2012-09-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6DXH
 | | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate | | Descriptor: | 4-(4-tert-butylphenyl)-4-oxobutanoic acid, UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ... | | Authors: | Harding, R.J, Mann, M.K, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Schapira, M, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-06-28 | | Release date: | 2018-07-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain.
J.Med.Chem., 62, 2019
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6DXT
 | | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoate | | Descriptor: | 1,2-ETHANEDIOL, 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoic acid, UNKNOWN ATOM OR ION, ... | | Authors: | Mann, M.K, Harding, R.J, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Schapira, M, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-06-29 | | Release date: | 2018-08-08 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain.
J.Med.Chem., 62, 2019
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1WFL
 | | Solution structure of the zf-AN1 domain from mouse zinc finger protein 216 | | Descriptor: | ZINC ION, Zinc finger protein 216 | | Authors: | Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-26 | | Release date: | 2004-11-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the zf-AN1 domain from mouse zinc finger protein 216
To be Published
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