PDB: 234 resultsInfo pagesStatus searchChemie searchBIRD

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2RK8	The Structure of rat cytosolic PEPCK in complex with phosphonoformate Descriptor: DI(HYDROXYETHYL)ETHER, FORMIC ACID, MANGANESE (II) ION, ... Authors: Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. Deposit date: 2007-10-16 Release date: 2008-01-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
2RKE	The Structure of rat cytosolic PEPCK in complex with sulfoacetate. Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... Authors: Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. Deposit date: 2007-10-16 Release date: 2008-01-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
2RK7	The Structure of rat cytosolic PEPCK in complex with oxalate Descriptor: MANGANESE (II) ION, OXALATE ION, Phosphoenolpyruvate carboxykinase, ... Authors: Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. Deposit date: 2007-10-16 Release date: 2008-01-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
4GMZ	Structure of rat cytosolic PEPCK Ld_2g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
3DT4	The structure of rat cytosolic PEPCK in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
4GMM	Structure of rat cytosolic PEPCK Ld_1g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.736 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GMW	Structure of rat cytosolic PEPCK Ld_1g in complex with PEP and GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
3DTB	The structure of rat cytosolic PEPCK in complex with phosphoglycolate and GDP Descriptor: 2-PHOSPHOGLYCOLIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BICARBONATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
4GMU	Structure of rat cytosolic PEPCK Ld_1g in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNQ	Structure of rat cytosolic PEPCK Ld_3g in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
3DT2	The structure of rat cytosolic PEPCK in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
4GNM	Structure of rat cytosolic PEPCK Ld_2g in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNP	Structure of rat cytosolic PEPCK Ld_3g in complex with PEP and GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.744 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
3DT7	The structure of rat cytosolic PEPCK in complex with beta-sulfopyruvate and GTP Descriptor: 2-ETHOXYETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
4GNO	Structure of rat cytosolic PEPCK Ld_3g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PENTAETHYLENE GLYCOL, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNL	Structure of rat cytosolic PEPCK Ld_2g in complex with PEP and GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
7LUO	N-terminus of Skp2 bound to Cyclin A Descriptor: S-phase kinase-associated protein 2,Cyclin-A2, Skp2 Motif 1 uncharacterized fragment 1, Skp2 Motif 1 uncharacterized fragment 2 Authors: Kelso, S, Ceccarelli, D.F, Sicheri, F. Deposit date: 2021-02-22 Release date: 2021-05-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.17 Å) Cite: Bipartite binding of the N terminus of Skp2 to cyclin A. Structure, 29, 2021
7NWK	Crystal structure of CDK9-Cyclin T1 bound by compound 6 Descriptor: Cyclin-T1, Cyclin-dependent kinase 9, N-((1R,3R)-3-(7-(4-fluoro-2-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl)cyclopentyl)acetamide Authors: Collie, G.W, Ferguson, A.D. Deposit date: 2021-03-16 Release date: 2021-10-27 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement. J.Med.Chem., 64, 2021
6CYT	HIV-1 TAR loop in complex with Tat:AFF4:P-TEFb Descriptor: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... Authors: Schulze Gahmen, U, Hurley, J.H. Deposit date: 2018-04-06 Release date: 2018-12-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2ISI	Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand Descriptor: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION, PHOSPHATE ION Authors: Agarwal, R, Naidu, M.D. Deposit date: 2006-10-17 Release date: 2006-10-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Crystal structure of hApe1 in a new crystal form with a bound ligand: implications on catalytic mechanism and its inhibition To be Published
1YNW	Crystal Structure of Vitamin D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element Descriptor: 5'-d(*TP*TP*AP*GP*GP*TP*CP*AP*CP*GP*AP*AP*GP*GP*TP*CP*AP*A)-3', 5'-d(*TP*TP*TP*GP*AP*CP*CP*TP*TP*CP*GP*TP*GP*AP*CP*CP*TP*A)-3', Retinoic acid receptor RXR-alpha, ... Authors: Shaffer, P.L, Gewirth, D.T. Deposit date: 2005-01-25 Release date: 2005-02-15 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural analysis of RXR-VDR interactions on DR3 DNA J.Steroid Biochem.Mol.Biol., 89-90, 2004
7QGS	Crystal structure of p300 CH1 domain in complex with CITIF (a CITED2-HIF-1alpha hybrid) Descriptor: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone acetyltransferase, ZINC ION Authors: Hegedus, Z, Wilson, A.J, Edwards, T.A. Deposit date: 2021-12-10 Release date: 2022-05-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Understanding p300-transcription factor interactions using sequence variation and hybridization. Rsc Chem Biol, 3, 2022
7CD5	mAPE1-blunt-ended dsDNA product complex Descriptor: DNA(5'-D(*CP*GP*TP*AP*AP*TP*AP*CP*G)-3'), DNA-(apurinic or apyrimidinic site) endonuclease Authors: Liu, T.C, Hsiao, Y.Y. Deposit date: 2020-06-18 Release date: 2021-01-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling. Nat Commun, 12, 2021
1K5K	Homonuclear 1H Nuclear Magnetic Resonance Assignment and Structural Characterization of HIV-1 Tat Mal Protein Descriptor: TAT protein Authors: Gregoire, C, Peloponese, J.M, Esquieu, D, Opi, S, Campbell, G, Solomiac, M, Lebrun, E, Lebreton, J, Loret, E.P. Deposit date: 2001-10-11 Release date: 2002-06-19 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein. Biopolymers, 62, 2001
8I0L	Structure of CDK9/cyclin T1 in complex with inhibitor Descriptor: 2-[(4-azanylcyclohexyl)amino]-7-cyclopentyl-~{N},~{N}-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Cyclin-T1, Cyclin-dependent kinase 9 Authors: Jiang, C, Ye, Y, Huang, Y. Deposit date: 2023-01-11 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structure of CDK9/cyclin T1 in complex with inhibitor To Be Published

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