8I0L

Structure of CDK9/cyclin T1 in complex with inhibitor

Summary for 8I0L

Entry DOI	10.2210/pdb8i0l/pdb
Descriptor	Cyclin-dependent kinase 9, Cyclin-T1, 2-[(4-azanylcyclohexyl)amino]-7-cyclopentyl-~{N},~{N}-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamide (3 entities in total)
Functional Keywords	cdk9, inhibitor, complex, cell invasion, cell invasion-inhibitor complex, cell invasion/inhibitor
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	68632.17
Authors	Jiang, C.,Ye, Y.,Huang, Y. (deposition date: 2023-01-11, release date: 2024-01-24)
Primary citation	Jiang, C.,Ye, Y.,Huang, Y. Structure of CDK9/cyclin T1 in complex with inhibitor To Be Published,
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation