8I0L

Structure of CDK9/cyclin T1 in complex with inhibitor

Summary for 8I0L

• Entry DOI: 10.2210/pdb8i0l/pdb
• Descriptor: Cyclin-dependent kinase 9, Cyclin-T1, 2-[(4-azanylcyclohexyl)amino]-7-cyclopentyl-~{N},~{N}-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamide (3 entities in total)
• Functional Keywords: cdk9, inhibitor, complex, cell invasion, cell invasion-inhibitor complex, cell invasion/inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 68632.17

Authors

Jiang, C.,Ye, Y.,Huang, Y. (deposition date: 2023-01-11, release date: 2024-01-24, Last modification date: 2024-11-06)

• Primary citation: Jiang, C.,Ye, Y.,Huang, Y.; Structure of CDK9/cyclin T1 in complex with inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.6 Å)