8OOC
 
 | | CryoEM Structure INO80core Hexasome complex Rvb core refinement state1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Chromatin-remodeling ATPase Ino80, ... | | Authors: | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | | Deposit date: | 2023-04-05 | | Release date: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
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7XJ1
 | | Structure of human TRPV3_G573S in complex with Trpvicin in C2 symmetry | | Descriptor: | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | Authors: | Fan, J, Yue, Z, Jiang, D, Lei, X. | | Deposit date: | 2022-04-14 | | Release date: | 2022-11-09 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structural basis of TRPV3 inhibition by an antagonist.
Nat.Chem.Biol., 19, 2023
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8F1D
 | | Voltage-gated potassium channel Kv3.1 apo | | Descriptor: | CHOLESTEROL, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1, ... | | Authors: | Chen, Y, Ishchenko, A. | | Deposit date: | 2022-11-04 | | Release date: | 2023-10-25 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels.
Proc.Natl.Acad.Sci.USA, 120, 2023
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4XBR
 | | In cellulo Crystal Structure of PAK4 in complex with Inka | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein FAM212A,Serine/threonine-protein kinase PAK 4 | | Authors: | Baskaran, Y, Ang, K.C, Anekal, P.V, Chan, W.L, Grimes, J.M, Manser, E, Robinson, R.C. | | Deposit date: | 2014-12-17 | | Release date: | 2015-12-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1
Nat Commun, 6, 2015
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8FVY
 | | 40S subunit of the Giardia lamblia 80S ribosome | | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... | | Authors: | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | | Deposit date: | 2023-01-20 | | Release date: | 2024-01-24 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Structure, 32, 2024
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7ZJD
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8G61
 | | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | | Deposit date: | 2023-02-14 | | Release date: | 2023-04-19 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
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7S7U
 | | Crystal structure of iNicSnFR3a Fluorescent Nicotine Sensor with nicotine bound | | Descriptor: | iNicSnFR 3.0 Fluorescent Nicotine Sensor | | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | | Deposit date: | 2021-09-17 | | Release date: | 2021-10-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands.
Elife, 11, 2022
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5XV4
 | | Crystal structure of ATG101-ATG13HORMA | | Descriptor: | Autophagy-related protein 101, Autophagy-related protein 13 | | Authors: | Kim, B.-W, Song, H.K. | | Deposit date: | 2017-06-26 | | Release date: | 2018-07-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
Autophagy, 14, 2018
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8PML
 | | Structure of Nal1 protein , SPIKE allele from japonica rice, construct 46-458 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein NARROW LEAF 1 | | Authors: | Huang, L.Y, Rety, S, Xi, X.G. | | Deposit date: | 2023-06-29 | | Release date: | 2024-04-17 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | The catalytic triad of rice NARROW LEAF1 involves H234.
Nat.Plants, 10, 2024
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6SKF
 | | Cryo-EM Structure of T. kodakarensis 70S ribosome | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Matzov, D, Sas-Chen, A, Thomas, J.M, Santangelo, T, Meier, J.L, Schwartz, S, Shalev-Benami, M. | | Deposit date: | 2019-08-15 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
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4M48
 | | X-ray structure of dopamine transporter elucidates antidepressant mechanism | | Descriptor: | 9D5 antibody, heavy chain, light chain, ... | | Authors: | Gouaux, E, Penmatsa, A, Wang, K. | | Deposit date: | 2013-08-06 | | Release date: | 2013-09-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.955 Å) | | Cite: | X-ray structure of dopamine transporter elucidates antidepressant mechanism.
Nature, 503, 2013
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8SLC
 | | High Affinity nanobodies against GFP | | Descriptor: | CHLORIDE ION, GLYCEROL, Green fluorescent protein, ... | | Authors: | Ketaren, N.E, Rout, M.P, Bonanno, J.B, Almo, S.C. | | Deposit date: | 2023-04-21 | | Release date: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | High Affinity nanobodies against GFP
To Be Published
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8RXX
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8G4E
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5LEM
 | | Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_11_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein | | Descriptor: | DD_Off7_11_3G124, Green fluorescent protein, Maltose-binding periplasmic protein | | Authors: | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | | Deposit date: | 2016-06-30 | | Release date: | 2017-08-02 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
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8PPK
 | | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | | Deposit date: | 2023-07-07 | | Release date: | 2023-10-18 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
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4BWZ
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3QLT
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4W6A
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4BDU
 | | Bax BH3-in-Groove dimer (GFP) | | Descriptor: | GREEN FLUORESCENT PROTEIN, APOPTOSIS REGULATOR BAX | | Authors: | Czabotar, P.E, Colman, P.M. | | Deposit date: | 2012-10-08 | | Release date: | 2013-02-13 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (2.998 Å) | | Cite: | Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Cell(Cambridge,Mass.), 152, 2013
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5HW9
 | | Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P21 | | Descriptor: | Green fluorescent protein | | Authors: | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | | Deposit date: | 2016-01-29 | | Release date: | 2017-02-01 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments
to be published
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7A1G
 | | Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | Authors: | Mackens-Kiani, T, Kratzat, H, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | Deposit date: | 2020-08-13 | | Release date: | 2020-10-14 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
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4U3M
 | | Crystal structure of Anisomycin bound to the yeast 80S ribosome | | Descriptor: | 18S rRNA, 25s rRNA, 40S ribosomal protein S0-A, ... | | Authors: | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | Deposit date: | 2014-07-22 | | Release date: | 2014-10-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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4U52
 | | Crystal structure of Nagilactone C bound to the yeast 80S ribosome | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | Deposit date: | 2014-07-24 | | Release date: | 2014-10-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
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