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8YY8
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BU of 8yy8 by Molmil
Fzd7 -Gs complex
Descriptor: Frizzled-7, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Chen, B, Xu, L, Han, G.W, Xu, F.
Deposit date:2024-04-03
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G s .
Cell Res., 31, 2021
1NXB
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BU of 1nxb by Molmil
STRUCTURE AND FUNCTION OF SNAKE VENOM CURARIMIMETIC NEUROTOXINS
Descriptor: NEUROTOXIN B, SULFATE ION
Authors:Tsernoglou, D, Petsko, G.A.
Deposit date:1980-08-08
Release date:1981-01-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure and function of snake venom curarimimetic neurotoxins.
Mol.Pharmacol., 14, 1978
2LQN
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BU of 2lqn by Molmil
Solution structure of CRKL
Descriptor: Crk-like protein
Authors:Jankowski, W, Saleh, T, Kalodimos, C.
Deposit date:2012-03-09
Release date:2012-05-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII.
Nat.Chem.Biol., 8, 2012
2LQW
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BU of 2lqw by Molmil
Solution structure of phosphorylated CRKL
Descriptor: Crk-like protein
Authors:Jankowski, W, Saleh, T, Kalodimos, C.
Deposit date:2012-03-16
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII.
Nat.Chem.Biol., 8, 2012
1FRA
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BU of 1fra by Molmil
TERTIARY STRUCTURE OF ERABUTOXIN B IN AQUEOUS SOLUTION ELUCIDATED BY TWO-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE
Descriptor: ERABUTOXIN B
Authors:Hatanaka, H, Kohda, D, Inagaki, F.
Deposit date:1994-03-28
Release date:1994-06-22
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Tertiary structure of erabutoxin b in aqueous solution as elucidated by two-dimensional nuclear magnetic resonance.
J.Mol.Biol., 240, 1994
3EI0
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BU of 3ei0 by Molmil
Structure of the E221A mutant of the Gloebacter violaceus pentameric ligand gated ion channnel (GLIC)
Descriptor: Glr4197 protein
Authors:Hilf, R.J.C, Dutzler, R.
Deposit date:2008-09-15
Release date:2008-11-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
Nature, 457, 2008
3EHZ
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BU of 3ehz by Molmil
X-ray structure of the pentameric ligand gated ion channel of Gloebacter violaceus (GLIC) in a presumptive open conformation
Descriptor: Glr4197 protein
Authors:Hilf, R.J.C, Dutzler, R.
Deposit date:2008-09-15
Release date:2008-11-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
Nature, 457, 2008
6ENS
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BU of 6ens by Molmil
Structure of mouse wild-type RKIP
Descriptor: ACETATE ION, GLYCEROL, Phosphatidylethanolamine-binding protein 1
Authors:Hirschbeck, M, Koelmel, W, Schindelin, H, Lorenz, K, Kisker, C.
Deposit date:2017-10-06
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ENT
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BU of 6ent by Molmil
Structure of the rat RKIP variant delta143-146
Descriptor: CHLORIDE ION, Phosphatidylethanolamine-binding protein 1, ZINC ION
Authors:Koelmel, W, Hirschbeck, M, Schindelin, H, Lorenz, K, Kisker, C.
Deposit date:2017-10-06
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8SL3
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BU of 8sl3 by Molmil
Human adenylyl Cyclase 5 in complex with Gbg
Descriptor: Adenylate cyclase type 5, GERAN-8-YL GERAN, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Yen, Y.C, Tesmer, J.J.G.
Deposit date:2023-04-20
Release date:2024-04-03
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structure of adenylyl cyclase 5 in complex with G beta gamma offers insights into ADCY5-related dyskinesia.
Nat.Struct.Mol.Biol., 2024
6VU5
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BU of 6vu5 by Molmil
Structure of G-alpha-q bound to its chaperone Ric-8A
Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, Resistance to inhibitors of cholinesterase-8A (Ric-8A)
Authors:Seven, A.B, Hilger, D.
Deposit date:2020-02-14
Release date:2020-03-18
Last modified:2020-03-25
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of G alpha Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.
Cell Rep, 30, 2020
2FQC
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BU of 2fqc by Molmil
Solution structure of conotoxin pl14a
Descriptor: Alpha/kappa-conotoxin pl14a
Authors:Craik, D.J, Daly, N.L.
Deposit date:2006-01-18
Release date:2006-07-18
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:A Novel Conotoxin Inhibitor of Kv1.6 Channel and nAChR Subtypes Defines a New Superfamily of Conotoxins
Biochemistry, 45, 2006
2MTT
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BU of 2mtt by Molmil
Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-cis dicarba RgIA
Descriptor: Dicarba Analogues of alpha-Conotoxin RgIA
Authors:Chhabra, S, Robinson, S.D, Norton, R.S.
Deposit date:2014-08-31
Release date:2014-11-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
2MTO
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BU of 2mto by Molmil
Non-reducible analogues of alpha-conotoxin RgIA: [2,8]-cis dicarba RgIA
Descriptor: Alpha-conotoxin RgIA
Authors:Chhabra, S, Robinson, S, Norton, R.
Deposit date:2014-08-26
Release date:2014-11-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
2MTU
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BU of 2mtu by Molmil
Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-trans dicarba RgIA
Descriptor: Dicarba Analogues of alpha-Conotoxin RgIA
Authors:Chhabra, S, Robinson, S.D, Norton, R.S.
Deposit date:2014-09-01
Release date:2014-11-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
4EKC
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BU of 4ekc by Molmil
Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(q) subunit alpha, MAGNESIUM ION, ...
Authors:Tesmer, J.J.G, Nance, M.R.
Deposit date:2012-04-09
Release date:2013-01-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (7.4 Å)
Cite:Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
Structure, 21, 2013
7AR7
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BU of 7ar7 by Molmil
Cryo-EM structure of Arabidopsis thaliana complex-I (open conformation)
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ...
Authors:Klusch, N, Kuelbrandt, W.
Deposit date:2020-10-23
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
4EKD
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BU of 4ekd by Molmil
Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, COBALT (II) ION, ...
Authors:Tesmer, J.J.G, Nance, M.R.
Deposit date:2012-04-09
Release date:2013-01-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
Structure, 21, 2013
4GNK
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BU of 4gnk by Molmil
Crystal structure of Galphaq in complex with full-length human PLCbeta3
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Lyon, A.M, Tesmer, J.J.G.
Deposit date:2012-08-17
Release date:2013-02-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Full-length G alpha (q)-phospholipase C-beta 3 structure reveals interfaces of the C-terminal coiled-coil domain.
Nat.Struct.Mol.Biol., 20, 2013
1HJE
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BU of 1hje by Molmil
Crystal structure of alpha-conotoxin SI
Descriptor: ALPHA-CONOTOXIN SI
Authors:Janes, R.W, Hargittai, B, Barany, G, Maclean, E.J, Teat, S.J.
Deposit date:2001-01-15
Release date:2003-06-26
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:The High Resolution Crystal Structure of Alpha-Conotoxin Si to 0.75 Angstroms
To be Published
3PFQ
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BU of 3pfq by Molmil
Crystal Structure and Allosteric Activation of Protein Kinase C beta II
Descriptor: CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein kinase C beta type, ...
Authors:Leonard, T.A, Rozycki, B, Saidi, L.F, Hummer, G, Hurley, J.H.
Deposit date:2010-10-28
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure and Allosteric Activation of Protein Kinase C beta II
Cell(Cambridge,Mass.), 144, 2011
4QJ4
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BU of 4qj4 by Molmil
Structure of a fragment of human phospholipase C-beta3 delta472-569, bound to IP3 and in complex with Galphaq
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ...
Authors:Lyon, A.M, Tesmer, J.J.G.
Deposit date:2014-06-03
Release date:2014-10-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular mechanisms of phospholipase C beta 3 autoinhibition.
Structure, 22, 2014
4QJ3
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BU of 4qj3 by Molmil
Structure of a fragment of human phospholipase C-beta3 delta472-559, in complex with Galphaq
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Lyon, A.M, Tesmer, J.J.G.
Deposit date:2014-06-03
Release date:2014-10-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular mechanisms of phospholipase C beta 3 autoinhibition.
Structure, 22, 2014
4QJ5
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BU of 4qj5 by Molmil
Structure of a fragment of human phospholipase C-beta3 delta472-581, bound to IP3 and in complex with Galphaq
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ...
Authors:Lyon, A.M, Tesmer, J.J.G.
Deposit date:2014-06-03
Release date:2014-10-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Molecular mechanisms of phospholipase C beta 3 autoinhibition.
Structure, 22, 2014
4Z90
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BU of 4z90 by Molmil
ELIC bound with the anesthetic isoflurane in the resting state
Descriptor: (2R)-2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Gamma-aminobutyric-acid receptor subunit beta-1
Authors:Chen, Q, Kinde, M, Arjunan, P, Cohen, A, Xu, Y, Tang, P.
Deposit date:2015-04-09
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.
Sci Rep, 5, 2015

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數據於2024-07-24公開中

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