8TO1
| Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter | Descriptor: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Darst, S.A, Saecker, R.M, Mueller, A.U. | Deposit date: | 2023-08-02 | Release date: | 2024-07-03 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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6NWL
| Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with hydrocortisone and PGC1a coregulator fragment | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Liu, X, Ortlund, E.A. | Deposit date: | 2019-02-06 | Release date: | 2019-10-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.595 Å) | Cite: | First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-ActivatedgammaCoactivator 1-alphaComplex with Endogenous and Synthetic Glucocorticoids. Mol.Pharmacol., 96, 2019
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8XA9
| Human MGME1 in complex with 5'-overhang DNA | Descriptor: | CALCIUM ION, DNA (11-MER), DNA (18-MER), ... | Authors: | Wu, C.C, Mao, E.Y.C. | Deposit date: | 2023-12-03 | Release date: | 2024-03-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural basis of how MGME1 processes DNA 5' ends to maintain mitochondrial genome integrity. Nucleic Acids Res., 52, 2024
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6NWK
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5LPX
| Crystal structure of PKC phosphorylation-mimicking mutant (S26E) Annexin A2 | Descriptor: | Annexin A2, CALCIUM ION, GLYCEROL | Authors: | Ecsedi, P, Gogl, G, Kiss, B, Nyitray, L. | Deposit date: | 2016-08-15 | Release date: | 2017-07-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding. Structure, 25, 2017
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8V07
| Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 30 days | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | Authors: | Yuan, M, Wilson, I.A. | Deposit date: | 2023-11-17 | Release date: | 2024-03-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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5LQ2
| Crystal structure of Tyr24 phosphorylated Annexin A2 at 3.4 A resolution | Descriptor: | Annexin A2, CALCIUM ION | Authors: | Ecsedi, P, Gogl, G, Kiss, B, Nyitray, L. | Deposit date: | 2016-08-15 | Release date: | 2017-07-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding. Structure, 25, 2017
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5LM7
| Crystal structure of the lambda N-Nus factor complex | Descriptor: | 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ... | Authors: | Said, N, Santos, K, Weber, G, Wahl, M.C. | Deposit date: | 2016-07-29 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural basis for lambda N-dependent processive transcription antitermination. Nat Microbiol, 2, 2017
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5LM9
| Structure of E. coli NusA | Descriptor: | MAGNESIUM ION, SULFATE ION, Transcription termination/antitermination protein NusA | Authors: | Said, N, Weber, G, Santos, K, Wahl, M.C. | Deposit date: | 2016-07-29 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.143 Å) | Cite: | Structural basis for lambda N-dependent processive transcription antitermination. Nat Microbiol, 2, 2017
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5LPU
| Crystal structure of Annexin A2 complexed with S100A4 | Descriptor: | Annexin A2, CALCIUM ION, GLYCEROL, ... | Authors: | Ecsedi, P, Gogl, G, Kiss, B, Nyitray, L. | Deposit date: | 2016-08-15 | Release date: | 2017-07-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding. Structure, 25, 2017
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5LQ0
| Crystal structure of Tyr24 phosphorylated Annexin A2 at 2.9 A resolution | Descriptor: | Annexin A2, CALCIUM ION | Authors: | Ecsedi, P, Gogl, G, Kiss, B, Nyitray, L. | Deposit date: | 2016-08-15 | Release date: | 2017-07-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding. Structure, 25, 2017
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8V06
| Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | Authors: | Yuan, M, Wilson, I.A. | Deposit date: | 2023-11-17 | Release date: | 2024-03-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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8V08
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8V05
| Crystal structure of mouse PLD3 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | Authors: | Yuan, M, Zhu, X, Wilson, I.A. | Deposit date: | 2023-11-17 | Release date: | 2024-03-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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7NYX
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7NYY
| Cryo-EM structure of the MukBEF monomer | Descriptor: | 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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7NZ4
| Cryo-EM structure of the MukBEF dimer | Descriptor: | 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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7NYW
| Cryo-EM structure of the MukBEF-MatP-DNA head module | Descriptor: | 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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7NZ2
| Cryo-EM structure of the MukBEF-MatP-DNA tetrad | Descriptor: | 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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7NYZ
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7NZ0
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7NZ3
| Cryo-EM structure of apposed MukBEF-MatP monomers on DNA | Descriptor: | 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | Authors: | Buermann, F, Lowe, J. | Deposit date: | 2021-03-23 | Release date: | 2021-07-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
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1EJ9
| CRYSTAL STRUCTURE OF HUMAN TOPOISOMERASE I DNA COMPLEX | Descriptor: | DNA (5'-D(*C*AP*AP*AP*AP*AP*GP*AP*CP*TP*CP*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*C*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*GP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3'), DNA TOPOISOMERASE I | Authors: | Redinbo, M.R, Champoux, J.J, Hol, W.G. | Deposit date: | 2000-03-01 | Release date: | 2000-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA. Biochemistry, 39, 2000
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1DML
| CRYSTAL STRUCTURE OF HERPES SIMPLEX UL42 BOUND TO THE C-TERMINUS OF HSV POL | Descriptor: | DNA POLYMERASE, DNA POLYMERASE PROCESSIVITY FACTOR | Authors: | Zuccola, H.J, Filman, D.J, Coen, D.M, Hogle, J.M. | Deposit date: | 1999-12-14 | Release date: | 2000-03-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. Mol.Cell, 5, 2000
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1FLZ
| URACIL DNA GLYCOSYLASE WITH UAAP | Descriptor: | URACIL, URACIL-DNA GLYCOSYLASE | Authors: | Werner, R.M, Jiang, Y.L, Gordley, R.G, Jagadeesh, G.J, Ladner, J.E, Xiao, G, Tordova, M, Gilliland, G.L, Stivers, J.T. | Deposit date: | 2000-08-15 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Stressing-out DNA? The contribution of serine-phosphodiester interactions in catalysis by uracil DNA glycosylase. Biochemistry, 39, 2000
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