2IHR
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![BU of 2ihr by Molmil](/molmil-images/mine/2ihr) | RF2 of Thermus thermophilus | Descriptor: | Peptide chain release factor 2 | Authors: | Dobbek, H, Voertler, C.S, Sprinzl, M. | Deposit date: | 2006-09-27 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Release factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies. Nucleic Acids Res., 35, 2007
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2IGV
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![BU of 2igv by Molmil](/molmil-images/mine/2igv) | CYCLOPHILIN 3 Complexed with DIPEPTIDE SER-PRO | Descriptor: | PROLINE, Peptidyl-prolyl cis-trans isomerase 3, SERINE | Authors: | Kan, D. | Deposit date: | 2006-09-25 | Release date: | 2007-08-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Experimental Determination of van der Waals Energies in a Biological System. Angew.Chem.Int.Ed.Engl., 46, 2007
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1I5X
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![BU of 1i5x by Molmil](/molmil-images/mine/1i5x) | HIV-1 GP41 CORE | Descriptor: | SULFATE ION, TRANSMEMBRANE GLYCOPROTEIN (GP41) | Authors: | Liu, J, Lu, M. | Deposit date: | 2001-03-01 | Release date: | 2002-09-10 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analysis of interhelical interactions in the human
immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning
mutagenesis. J.Virol., 75, 2001
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6G24
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![BU of 6g24 by Molmil](/molmil-images/mine/6g24) | X-ray structure of NSD3-PWWP1 in complex with compound 3 | Descriptor: | 2-[(~{E})-2-thiophen-2-ylethenyl]benzoic acid, Histone-lysine N-methyltransferase NSD3 | Authors: | Boettcher, J, Muellauer, B.J, Weiss-Puxbaum, A, Zoephel, A. | Deposit date: | 2018-03-22 | Release date: | 2019-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat.Chem.Biol., 15, 2019
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6G2C
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![BU of 6g2c by Molmil](/molmil-images/mine/6g2c) | X-ray structure of NSD3-PWWP1 in complex with compound 9 | Descriptor: | 3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)-1,2-oxazole, Histone-lysine N-methyltransferase NSD3 | Authors: | Boettcher, J, Muellauer, B.J, Weiss-Puxbaum, A, Zoephel, A. | Deposit date: | 2018-03-22 | Release date: | 2019-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat.Chem.Biol., 15, 2019
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2IGM
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![BU of 2igm by Molmil](/molmil-images/mine/2igm) | Crystal structure of recombinant pyranose 2-oxidase H548N mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose oxidase | Authors: | Divne, C. | Deposit date: | 2006-09-22 | Release date: | 2006-10-10 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for substrate binding and regioselective oxidation of monosaccharides at c3 by pyranose 2-oxidase. J.Biol.Chem., 281, 2006
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2JXY
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![BU of 2jxy by Molmil](/molmil-images/mine/2jxy) | Solution structure of the hemopexin-like domain of MMP12 | Descriptor: | CALCIUM ION, Macrophage metalloelastase | Authors: | Bertini, I, Calderone, V, Fragai, M, Jaiswal, R, Luchinat, C, Melikian, M. | Deposit date: | 2007-12-01 | Release date: | 2008-05-27 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 J.Am.Chem.Soc., 130, 2008
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6G2O
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![BU of 6g2o by Molmil](/molmil-images/mine/6g2o) | X-ray structure of NSD3-PWWP1 in complex with compound BI-9321 | Descriptor: | Histone-lysine N-methyltransferase NSD3, [4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-phenyl]methanamine | Authors: | Boettcher, J, Muellauer, B.J, Weiss-Puxbaum, A, Zoephel, A. | Deposit date: | 2018-03-23 | Release date: | 2019-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat.Chem.Biol., 15, 2019
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6WGT
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![BU of 6wgt by Molmil](/molmil-images/mine/6wgt) | Crystal structure of HTR2A with hallucinogenic agonist | Descriptor: | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562 fusion, CHOLESTEROL, ... | Authors: | Kim, K.L, Che, T, Krumm, B.E, Roth, B.L. | Deposit date: | 2020-04-06 | Release date: | 2020-09-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure of a Hallucinogen-Activated Gq-Coupled 5-HT 2A Serotonin Receptor Cell(Cambridge,Mass.), 182, 2020
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7UL2
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![BU of 7ul2 by Molmil](/molmil-images/mine/7ul2) | CryoEM Structure of Inactive NTSR1 Bound to SR48692 and Nb6 | Descriptor: | 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Nanobody 6, Neurotensin receptor 1, ... | Authors: | Robertson, M.J, Skiniotis, G. | Deposit date: | 2022-04-03 | Release date: | 2022-06-29 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29, 2022
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1KDF
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![BU of 1kdf by Molmil](/molmil-images/mine/1kdf) | NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | ANTIFREEZE PROTEIN | Authors: | Sonnichsen, F.D, Deluca, C.I, Davies, P.L, Sykes, B.D. | Deposit date: | 1996-07-08 | Release date: | 1997-04-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction. Structure, 4, 1996
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1JMX
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![BU of 1jmx by Molmil](/molmil-images/mine/1jmx) | |
1JD3
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![BU of 1jd3 by Molmil](/molmil-images/mine/1jd3) | Chorismate lyase G90A mutant with bound product | Descriptor: | P-HYDROXYBENZOIC ACID, chorismate lyase | Authors: | Mayhew, M, Smith, N, Holden, M.J, Gallagher, D.T. | Deposit date: | 2001-06-12 | Release date: | 2001-06-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural analysis of ligand binding and catalysis in chorismate lyase. Arch.Biochem.Biophys., 445, 2006
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6G27
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![BU of 6g27 by Molmil](/molmil-images/mine/6g27) | X-ray structure of NSD3-PWWP1 in complex with compound 5 | Descriptor: | 5-methyl-6-phenyl-2-piperidin-4-yl-pyridazin-3-one, Histone-lysine N-methyltransferase NSD3 | Authors: | Boettcher, J, Muellauer, B.J, Weiss-Puxbaum, A, Zoephel, A. | Deposit date: | 2018-03-22 | Release date: | 2019-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat.Chem.Biol., 15, 2019
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1K33
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![BU of 1k33 by Molmil](/molmil-images/mine/1k33) | Crystal structure analysis of the gp41 core mutant | Descriptor: | Transmembrane glycoprotein GP41 | Authors: | Shu, W, Lu, M. | Deposit date: | 2001-10-01 | Release date: | 2001-10-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion. Biochemistry, 41, 2002
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1JES
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![BU of 1jes by Molmil](/molmil-images/mine/1jes) | Crystal Structure of a Copper-Mediated Base Pair in DNA | Descriptor: | 5'-D(*CP*GP*CP*GP*(DPY)P*AP*TP*(DRP)P*CP*GP*CP*G)-3', COPPER (II) ION | Authors: | Atwell, S, Meggers, E, Spraggon, G, Schultz, P.G. | Deposit date: | 2001-06-18 | Release date: | 2001-11-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a Copper-Mediated Base Pair in DNA J.Am.Chem.Soc., 123, 2001
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6G29
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![BU of 6g29 by Molmil](/molmil-images/mine/6g29) | X-ray structure of NSD3-PWWP1 in complex with compound 6 | Descriptor: | 5-methyl-2-piperidin-4-yl-6-pyridin-4-yl-pyridazin-3-one, Histone-lysine N-methyltransferase NSD3 | Authors: | Boettcher, J, Muellauer, B.J, Weiss-Puxbaum, A, Zoephel, A. | Deposit date: | 2018-03-22 | Release date: | 2019-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat.Chem.Biol., 15, 2019
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6G2E
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![BU of 6g2e by Molmil](/molmil-images/mine/6g2e) | X-ray structure of NSD3-PWWP1 in complex with compound 13 | Descriptor: | Histone-lysine N-methyltransferase NSD3, [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine | Authors: | Boettcher, J, Muellauer, B.J, Weiss-Puxbaum, A, Zoephel, A. | Deposit date: | 2018-03-23 | Release date: | 2019-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat.Chem.Biol., 15, 2019
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6HR0
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![BU of 6hr0 by Molmil](/molmil-images/mine/6hr0) | |
7KDT
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![BU of 7kdt by Molmil](/molmil-images/mine/7kdt) | |
7K7L
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![BU of 7k7l by Molmil](/molmil-images/mine/7k7l) | |
7UL5
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![BU of 7ul5 by Molmil](/molmil-images/mine/7ul5) | |
7UL3
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![BU of 7ul3 by Molmil](/molmil-images/mine/7ul3) | CryoEM Structure of Inactive H2R Bound to Famotidine, Nb6M, and NabFab | Descriptor: | Histamine H2 receptor, NabFab HC, NabFab LC, ... | Authors: | Robertson, M.J, Skiniotis, G. | Deposit date: | 2022-04-03 | Release date: | 2022-06-29 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29, 2022
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2H99
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![BU of 2h99 by Molmil](/molmil-images/mine/2h99) | Crystal structure of the effector binding domain of a BenM variant (R156H,T157S) | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C. | Deposit date: | 2006-06-09 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1. Mol.Microbiol., 72, 2009
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2H9B
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![BU of 2h9b by Molmil](/molmil-images/mine/2h9b) | Crystal structure of the effector binding domain of a BenM variant (BenM R156H/T157S) | Descriptor: | CHLORIDE ION, HTH-type transcriptional regulator benM, SULFATE ION | Authors: | Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C. | Deposit date: | 2006-06-09 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1. Mol.Microbiol., 72, 2009
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