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8BSC
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BU of 8bsc by Molmil
CryoEM structure of the RAD51 nucleoprotein filament in the presence of ADP and Ca2+
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, DNA repair protein RAD51 homolog 1
Authors:Appleby, R, Bollschweiler, D, Pellegrini, L.
Deposit date:2022-11-24
Release date:2023-05-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly.
Iscience, 26, 2023
5E01
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BU of 5e01 by Molmil
Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to palyndromic promoter DNA
Descriptor: 5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3', Uncharacterized HTH-type transcriptional regulator HI_0186
Authors:Counago, R.M, Chang, C.W, Chen, N.H, Djoko, K.Y, McEwan, A.G, Kobe, B.
Deposit date:2015-09-26
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
Nucleic Acids Res., 44, 2016
2GIH
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BU of 2gih by Molmil
Q138F HincII bound to cognate DNA GTCGAC and Ca2+
Descriptor: 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*GP*C)-3', CALCIUM ION, Type II restriction enzyme HincII
Authors:Horton, N.C, Joshi, H.K, Etzkorn, C, Chatwell, L, Bitinaite, J.
Deposit date:2006-03-28
Release date:2006-07-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Alteration of Sequence Specificity of the Type II Restriction Endonuclease HincII through an Indirect Readout Mechanism.
J.Biol.Chem., 281, 2006
3KHR
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BU of 3khr by Molmil
Dpo4 post-extension ternary complex with the correct C opposite the 2-aminofluorene-guanine [AF]G lesion
Descriptor: 2-AMINOFLUORENE, 5'-D(*CP*C*TP*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3', ...
Authors:Rechkoblit, O, Malinina, L, Patel, D.J.
Deposit date:2009-10-30
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
Nat.Struct.Mol.Biol., 17, 2010
5VU7
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BU of 5vu7 by Molmil
TNA polymerase, open ternary complex
Descriptor: 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ...
Authors:Chim, N, Chaput, J.C.
Deposit date:2017-05-18
Release date:2017-12-06
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural basis for TNA synthesis by an engineered TNA polymerase.
Nat Commun, 8, 2017
4F1I
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BU of 4f1i by Molmil
Crystal structure of SeMet TDP2 from Caenorhabditis elegans
Descriptor: 5'-tyrosyl-DNA phosphodiesterase, GLYCEROL
Authors:Shi, K, Kurahashi, K, Aihara, H.
Deposit date:2012-05-07
Release date:2012-10-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Nat.Struct.Mol.Biol., 19, 2012
3U3W
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BU of 3u3w by Molmil
Crystal Structure of Bacillus thuringiensis PlcR in complex with the peptide PapR7 and DNA
Descriptor: 5'-D(P*AP*TP*AP*TP*GP*AP*AP*AP*TP*AP*TP*TP*GP*CP*AP*TP*AP*G)-3', 5'-D(P*CP*TP*AP*TP*GP*CP*AP*AP*TP*AP*TP*TP*TP*CP*AP*TP*AP*T)-3', C-terminus heptapeptide from PapR protein, ...
Authors:Grenha, R, Slamti, L, Bouillaut, L, Lereclus, D, Nessler, S.
Deposit date:2011-10-06
Release date:2013-01-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR.
Proc.Natl.Acad.Sci.USA, 110, 2013
8GLX
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BU of 8glx by Molmil
CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:Shen, Y, Guarne, A.
Deposit date:2023-03-23
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
2XWC
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BU of 2xwc by Molmil
Crystal structure of the DNA binding domain of human TP73 refined at 1.8 A resolution
Descriptor: GLYCEROL, TRIS(HYDROXYETHYL)AMINOMETHANE, TUMOUR PROTEIN P73, ...
Authors:Canning, P, Zhang, Y, Vollmar, M, Krojer, T, Ugochukwu, E, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2010-11-03
Release date:2010-11-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73.
J.Mol.Biol., 423, 2012
8GLW
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BU of 8glw by Molmil
CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:Shen, Y, Guarne, A.
Deposit date:2023-03-23
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
6R4S
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BU of 6r4s by Molmil
Crystal structure of the Pri1 subunit of human primase bound to ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA primase small subunit, MANGANESE (II) ION, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
7CVQ
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BU of 7cvq by Molmil
crystal structure of Arabidopsis CO CCT domain in complex with NF-YB2/YC3 and FT CORE1 DNA
Descriptor: Chimera of Nuclear transcription factor Y subunit C-3 and Zinc finger protein CONSTANS, FT CORE1 DNA forward strand, FT CORE1 DNA reverse strand, ...
Authors:Lv, X, Du, J.
Deposit date:2020-08-26
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex.
Plant Cell, 33, 2021
7CVO
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BU of 7cvo by Molmil
crystal structure of Arabidopsis CO CCT domain in complex with NF-YB3/YC4 and FT CORE2 DNA
Descriptor: Chimera of Nuclear transcription factor Y subunit C-4 and Zinc finger protein CONSTANS, FT CORE2 DNA forward strand, FT CORE2 DNA reverse strand, ...
Authors:Lv, X, Du, J.
Deposit date:2020-08-26
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex.
Plant Cell, 33, 2021
6R4T
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BU of 6r4t by Molmil
Crystal structure of the Pri1 subunit of human primase bound to vidarabine triphosphate
Descriptor: 1,2-ETHANEDIOL, 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-amine, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
1VQB
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BU of 1vqb by Molmil
GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor: GENE V PROTEIN
Authors:Skinner, M.M, Zhang, H, Leschnitzer, D.H, Guan, Y, Bellamy, H, Sweet, R.M, Gray, C.W, Konings, R.N.H, Wang, A.H.-J, Terwilliger, T.C.
Deposit date:1996-08-14
Release date:1997-02-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein.
Proc.Natl.Acad.Sci.USA, 91, 1994
6R5E
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BU of 6r5e by Molmil
Crystal structure of the Pri1 subunit of human primase bound to 2F-ATP
Descriptor: 1,2-ETHANEDIOL, 2-fluoro-ATP, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6RB4
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BU of 6rb4 by Molmil
Crystal structure of the Pri1 subunit of human primase
Descriptor: 1,2-ETHANEDIOL, DNA primase small subunit, ZINC ION
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-04-09
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R5D
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BU of 6r5d by Molmil
Crystal structure of the Pri1 subunit of human primase bound to dATP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R4U
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BU of 6r4u by Molmil
Crystal structure of the Pri1 subunit of human primase bound to fludarabine triphosphate
Descriptor: 1,2-ETHANEDIOL, 2-fluoro-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-a mine, DNA primase small subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2019-03-24
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
4FB3
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BU of 4fb3 by Molmil
Polyomavirus T-ag binds symmetrical repeats at the viral origin in an asymmetrical manner
Descriptor: Large T antigen, ORI DNA oligonucleotide-Crick strand, ORI DNA oligonucleotide-Watson strand
Authors:Bohm, A, Harrison, C.J, Schaffhausen, B.S, Jiang, T.
Deposit date:2012-05-22
Release date:2013-10-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Polyomavirus large T antigen binds symmetrical repeats at the viral origin in an asymmetrical manner.
J.Virol., 87, 2013
1ID3
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BU of 1id3 by Molmil
CRYSTAL STRUCTURE OF THE YEAST NUCLEOSOME CORE PARTICLE REVEALS FUNDAMENTAL DIFFERENCES IN INTER-NUCLEOSOME INTERACTIONS
Descriptor: HISTONE H2A.1, HISTONE H2B.2, HISTONE H3, ...
Authors:White, C.L, Suto, R.K, Luger, K.
Deposit date:2001-04-03
Release date:2001-09-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions.
EMBO J., 20, 2001
5LAR
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BU of 5lar by Molmil
Crystal structure of p38 alpha MAPK14 in complex with VPC00628
Descriptor: 5-azanyl-~{N}-[[4-[[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide, Mitogen-activated protein kinase 14
Authors:Chaikuad, A, Petersen, L.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2016-06-14
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Novel p38alpha MAP kinase inhibitors identified from yoctoReactor DNA-encoded small molecule library
Medchemcomm, 7, 2016
4OB4
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BU of 4ob4 by Molmil
Structure of the S. venezulae BldD DNA-binding domain
Descriptor: Putative DNA-binding protein
Authors:schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R.
Deposit date:2014-01-06
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell(Cambridge,Mass.), 158, 2014
1HNI
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BU of 1hni by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION
Descriptor: (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66)
Authors:Ding, J, Das, K, Arnold, E.
Deposit date:1995-02-28
Release date:1995-06-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.
Structure, 3, 1995
7DHY
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BU of 7dhy by Molmil
Arsenic-bound p53 DNA-binding domain mutant G245S
Descriptor: ARSENIC, Cellular tumor antigen p53, GLYCEROL, ...
Authors:Chen, S, Lu, M.
Deposit date:2020-11-18
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell, 39, 2021

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數據於2024-09-04公開中

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