6LKQ
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![BU of 6lkq by Molmil](/molmil-images/mine/6lkq) | The Structural Basis for Inhibition of Ribosomal Translocation by Viomycin | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Zhang, L, Wang, Y.H, Lancaster, L, Zhou, J, Noller, H.F. | Deposit date: | 2019-12-20 | Release date: | 2020-05-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The structural basis for inhibition of ribosomal translocation by viomycin. Proc.Natl.Acad.Sci.USA, 117, 2020
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8AZW
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![BU of 8azw by Molmil](/molmil-images/mine/8azw) | Cryo-EM structure of the plant 60S subunit | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | Deposit date: | 2022-09-06 | Release date: | 2023-06-07 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.14 Å) | Cite: | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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1N8R
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![BU of 1n8r by Molmil](/molmil-images/mine/1n8r) | Structure of large ribosomal subunit in complex with virginiamycin M | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ... | Authors: | Hansen, J.L, Moore, P.B, Steitz, T.A. | Deposit date: | 2002-11-21 | Release date: | 2003-07-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
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8H69
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![BU of 8h69 by Molmil](/molmil-images/mine/8h69) | Cryo-EM structure of influenza RNA polymerase | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ... | Authors: | Li, H, Wu, Y, Liang, H, Liu, Y. | Deposit date: | 2022-10-16 | Release date: | 2023-06-28 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles. Nat.Struct.Mol.Biol., 30, 2023
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1NJI
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![BU of 1nji by Molmil](/molmil-images/mine/1nji) | Structure of chloramphenicol bound to the 50S ribosomal subunit | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ... | Authors: | Hansen, J.L, Moore, P.B, Steitz, T.A. | Deposit date: | 2002-12-31 | Release date: | 2003-07-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
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7WTO
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![BU of 7wto by Molmil](/molmil-images/mine/7wto) | Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Tsr1-1 (without Rps2) | Descriptor: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | Authors: | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | Deposit date: | 2022-02-05 | Release date: | 2022-10-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
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7YFE
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![BU of 7yfe by Molmil](/molmil-images/mine/7yfe) | In situ structure of polymerase complex of mammalian reovirus in virion | Descriptor: | Lambda-2 protein, Mu-2 protein, RNA (5'-R(P*AP*CP*GP*AP*UP*UP*AP*GP*C)-3'), ... | Authors: | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | Deposit date: | 2022-07-08 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7APK
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![BU of 7apk by Molmil](/molmil-images/mine/7apk) | Structure of the human THO - UAP56 complex | Descriptor: | Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... | Authors: | Hohmann, U, Puehringer, T, Plaschka, C. | Deposit date: | 2020-10-17 | Release date: | 2020-12-16 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the human core transcription-export complex reveals a hub for multivalent interactions. Elife, 9, 2020
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7YED
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![BU of 7yed by Molmil](/molmil-images/mine/7yed) | In situ structure of polymerase complex of mammalian reovirus in the elongation state | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Lambda-2 protein, MAGNESIUM ION, ... | Authors: | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | Deposit date: | 2022-07-05 | Release date: | 2023-04-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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8VA2
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![BU of 8va2 by Molmil](/molmil-images/mine/8va2) | |
6I9B
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![BU of 6i9b by Molmil](/molmil-images/mine/6i9b) | NMR structure of the La module from human LARP4A | Descriptor: | La-related protein 4 | Authors: | Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R. | Deposit date: | 2018-11-22 | Release date: | 2019-03-13 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA. Nucleic Acids Res., 47, 2019
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1FJG
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![BU of 1fjg by Molmil](/molmil-images/mine/1fjg) | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V. | Deposit date: | 2000-08-08 | Release date: | 2000-09-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics Nature, 407, 2000
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4CXH
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![BU of 4cxh by Molmil](/molmil-images/mine/4cxh) | Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement | Descriptor: | 18S RRNA - H44, 18S RRNA - H5-H14, 18S RRNA - H8, ... | Authors: | Budkevich, T.V, Giesebrecht, J, Behrmann, E, Loerke, J, Ramrath, D.J.F, Mielke, T, Ismer, J, Hildebrand, P, Tung, C.-S, Nierhaus, K.H, Sanbonmatsu, K.Y, Spahn, C.M.T. | Deposit date: | 2014-04-07 | Release date: | 2014-07-16 | Last modified: | 2019-06-26 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement. Cell(Cambridge,Mass.), 158, 2014
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8PBL
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![BU of 8pbl by Molmil](/molmil-images/mine/8pbl) | |
6NNB
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![BU of 6nnb by Molmil](/molmil-images/mine/6nnb) | |
5EKZ
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![BU of 5ekz by Molmil](/molmil-images/mine/5ekz) | Crystal structure of mouse Taco1 | Descriptor: | Translational activator of cytochrome c oxidase 1 | Authors: | Spahr, H, Richman, T.R, Larsson, N.G, Rackham, O, Filipovska, A. | Deposit date: | 2015-11-04 | Release date: | 2016-06-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun, 7, 2016
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7ZPL
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![BU of 7zpl by Molmil](/molmil-images/mine/7zpl) | |
8GU3
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![BU of 8gu3 by Molmil](/molmil-images/mine/8gu3) | |
5ZMD
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![BU of 5zmd by Molmil](/molmil-images/mine/5zmd) | Crystal structure of FTO in complex with m6dA modified ssDNA | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ... | Authors: | Zhang, X, Wei, L.H, Luo, J, Xiao, Y, Liu, J, Zhang, W, Zhang, L, Jia, G.F. | Deposit date: | 2018-04-02 | Release date: | 2019-04-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5MS0
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![BU of 5ms0 by Molmil](/molmil-images/mine/5ms0) | |
8C9A
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![BU of 8c9a by Molmil](/molmil-images/mine/8c9a) | Cryo-EM captures early ribosome assembly in action | Descriptor: | 23S rRNA, 50S ribosomal protein L22, 50S ribosomal protein L23, ... | Authors: | Lauer, S, Nikolay, R, Qin, B. | Deposit date: | 2023-01-21 | Release date: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (4.86 Å) | Cite: | Cryo-EM captures early ribosome assembly in action. Nat Commun, 14, 2023
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7N85
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![BU of 7n85 by Molmil](/molmil-images/mine/7n85) | Inner ring spoke from the isolated yeast NPC | Descriptor: | Nucleoporin ASM4, Nucleoporin NIC96, Nucleoporin NSP1, ... | Authors: | Akey, C.W, Rout, M.P, Ouch, C, Echevarria, I, Fernandez-Martinez, J, Nudelman, I. | Deposit date: | 2021-06-13 | Release date: | 2022-01-26 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell, 185, 2022
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4CXG
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![BU of 4cxg by Molmil](/molmil-images/mine/4cxg) | Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement | Descriptor: | 18S RRNA - H44, 18S RRNA - H5-H14, 18S RRNA - H8, ... | Authors: | Budkevich, T.V, Giesebrecht, J, Behrmann, E, Loerke, J, Ramrath, D.J.F, Mielke, T, Ismer, J, Hildebrand, P, Tung, C.-S, Nierhaus, K.H, Sanbonmatsu, K.Y, Spahn, C.M.T. | Deposit date: | 2014-04-07 | Release date: | 2014-07-16 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement. Cell(Cambridge,Mass.), 158, 2014
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3SWN
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![BU of 3swn by Molmil](/molmil-images/mine/3swn) | Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1 7 and LSm2 8 Rings | Descriptor: | U6 snRNA-associated Sm-like protein LSm5, U6 snRNA-associated Sm-like protein LSm6, U6 snRNA-associated Sm-like protein LSm7, ... | Authors: | Mund, M, Neu, A, Ullmann, J.L, Neu, U, Sprangers, R. | Deposit date: | 2011-07-14 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the LSm657 complex: an assembly intermediate of the LSm1-7 and LSm2-8 rings. J.Mol.Biol., 414, 2011
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6T0W
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![BU of 6t0w by Molmil](/molmil-images/mine/6t0w) | Human Influenza B polymerase recycling complex | Descriptor: | Polymerase PB2, Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, ... | Authors: | Wandzik, J.M, Kouba, T, Karuppasamy, M, Cusack, S. | Deposit date: | 2019-10-03 | Release date: | 2020-04-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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