PDB: 5689 resultsInfo pagesStatus searchChemie searchBIRD

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1NB4	HC-J4 RNA polymerase apo-form Descriptor: polyprotein Authors: Jaeger, J, O'Farrell, D.J, Trowbridge, R, Rowlands, D.J. Deposit date: 2002-12-02 Release date: 2003-03-25 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
1NB6	HC-J4 RNA polymerase complexed with UTP Descriptor: MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, polyprotein Authors: O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J. Deposit date: 2002-12-02 Release date: 2003-03-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
1JY4	B4DIMER: A DE NOVO DESIGNED EIGHT-STRANDED BETA-SHEET ASSEMBLED USING A DISULFIDE BOND Descriptor: B4DIMER Authors: Venkatraman, J, Nagana Gowda, G.A, Balaram, P. Deposit date: 2001-09-11 Release date: 2002-06-12 Last modified: 2024-11-06 Method: SOLUTION NMR Cite: Design and construction of an open multistranded beta-sheet polypeptide stabilized by a disulfide bridge. J.Am.Chem.Soc., 124, 2002
1JY6	B4DIMERA: A DE NOVO DESIGNED FOUR-STRANDED BETA-SHEET ASSEMBLED USING A DISULFIDE BOND Descriptor: B4DIMER Authors: Venkatraman, J, Nagana Gowda, G.A, Balaram, P. Deposit date: 2001-09-11 Release date: 2002-06-12 Last modified: 2024-10-30 Method: SOLUTION NMR Cite: Design and construction of an open multistranded beta-sheet polypeptide stabilized by a disulfide bridge. J.Am.Chem.Soc., 124, 2002
9FKD	Progesterone-bound DB3 Fab in complex with computationally designed DBPro1156_2 protein binder Descriptor: Anti-kappa Fab Heavy Chain, Anti-kappa Fab Light Chain, DB3 Fab Heavy chain, ... Authors: Pacesa, M, Marchand, A, Correia, B.E. Deposit date: 2024-06-03 Release date: 2024-10-30 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Targeting protein-ligand neosurfaces using a generalizable deep learning approach To Be Published
5BYO	Computationally designed left-handed alpha/alpha toroid with 12 repeats Descriptor: dTor_12x31L Authors: Doyle, L, Stoddard, B.L, Bradley, P. Deposit date: 2015-06-10 Release date: 2015-12-16 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Rational design of alpha-helical tandem repeat proteins with closed architectures. Nature, 528, 2015
7KUW	High-throughput design and refinement of stable proteins using sequence-only models Descriptor: Sequence-Based Designed Protein nmt_0994_guided_02 Authors: Bera, A.K, Stewart, L, Kang, A.S, Baker, D. Deposit date: 2020-11-25 Release date: 2021-12-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Large-scale design and refinement of stable proteins using sequence-only models. Plos One, 17, 2022
4ADP	HCV-J6 NS5B POLYMERASE V405I MUTANT Descriptor: RNA-DIRECTED RNA POLYMERASE Authors: Scrima, N, Bressanelli, S. Deposit date: 2012-01-02 Release date: 2012-05-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.902 Å) Cite: Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405. J.Virol., 86, 2012
4AEP	HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE Authors: Caillet-Saguy, C, Bressanelli, S. Deposit date: 2012-01-12 Release date: 2012-05-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405. J.Virol., 86, 2012
4AEX	HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM in a primitive orthorhombic space group Descriptor: PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE Authors: Caillet-Saguy, C, Bressanelli, S. Deposit date: 2012-01-12 Release date: 2012-05-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405. J.Virol., 86, 2012
5HKN	Crystal structure de novo designed fullerene organizing protein complex with fullerene Descriptor: (C_{60}-I_{h})[5,6]fullerene, fullerene organizing protein Authors: Paul, J, Acharya, R, Kim, K.-H, Kim, Y.H, Kim, N.H, Grigoryan, G, DeGardo, W.F. Deposit date: 2016-01-14 Release date: 2016-05-04 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.761 Å) Cite: Protein-directed self-assembly of a fullerene crystal. Nat Commun, 7, 2016
5HKR	Crystal structure of de novo designed fullerene organising protein complex with fullerene Descriptor: (C_{60}-I_{h})[5,6]fullerene, fullerene organizing protein Authors: Acharya, R, Kim, Y.H, Grigoryan, G, DeGardo, W.F. Deposit date: 2016-01-14 Release date: 2016-05-04 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Protein-directed self-assembly of a fullerene crystal. Nat Commun, 7, 2016
7T2Y	X-ray structure of a designed cold unfolding four helix bundle Descriptor: Designed cold unfolding four helix bundle Authors: Harrison, J.S, Kuhlman, B, Szyperski, T, Premkumar, L, Maguire, J, Pulavarti, S, Yuen, S. Deposit date: 2021-12-06 Release date: 2022-03-02 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.34 Å) Cite: From Protein Design to the Energy Landscape of a Cold Unfolding Protein. J.Phys.Chem.B, 126, 2022
7SMJ	F2N structure, protein design with deep learning Descriptor: AI-designed TIM-barrel F2N Authors: Mathews, I.I, Anand-Achim, N, Huang, P. Deposit date: 2021-10-26 Release date: 2022-03-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Protein sequence design with a learned potential. Nat Commun, 13, 2022
4RJV	Crystal Structure of a De Novo Designed Ferredoxin Fold, Northeast Structural Genomics Consortium (NESG) Target OR461 Descriptor: OR461 Authors: O'Connell, P.T, Lin, Y.-R, Guan, R, Koga, N, Koga, R, Seetharaman, J, Janjua, H, Xiao, R, Maglaqui, M, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2014-10-09 Release date: 2014-10-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.523 Å) Cite: Northeast Structural Genomics Consortium Target OR461 To be published
1LT1	SLIDING HELIX INDUCED CHANGE OF COORDINATION GEOMETRY IN A MODEL DI-MN(II) PROTEIN Descriptor: L13G-DF1, MANGANESE (II) ION Authors: Di Costanzo, L, Geremia, S. Deposit date: 2002-05-20 Release date: 2003-05-20 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Sliding helix and change of coordination geometry in a model di-MnII protein Angew.Chem.Int.Ed.Engl., 42, 2003
1N0D	Stability of cyclic beta-hairpins: Asymmetric contibutions from side chains of hydrogen bonded cross-strand residue pair Descriptor: bhp_VWLH, disulfide cyclized beta-hairpin peptide Authors: Russell, S.J, Blandl, T, Skelton, N.J, Cochran, A.G. Deposit date: 2002-10-11 Release date: 2003-02-04 Last modified: 2024-10-30 Method: SOLUTION NMR Cite: Stability of Cyclic Beta-Hairpins: Asymmetric Contributions From Side Chains of Hydrogen Bonded Cross-Strand Residue Pair J.Am.Chem.Soc., 125, 2003
6NL9	Crystal structure of de novo designed metal-controlled dimer of mutant B1 immunoglobulin-binding domain of Streptococcal Protein G (L12H, T16L, V29H, Y33H, N37L)-apo Descriptor: Immunoglobulin G-binding protein G, MAGNESIUM ION, SODIUM ION Authors: Maniaci, B, Stec, B, Huxford, T. Deposit date: 2019-01-08 Release date: 2019-01-23 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Design of High-Affinity Metal-Controlled Protein Dimers. Biochemistry, 58, 2019
3JCI	2.9 Angstrom Resolution Cryo-EM 3-D Reconstruction of Close-packed PCV2 Virus-like Particles Descriptor: Capsid protein Authors: Liu, Z, Guo, F, Wang, F, Li, T.C, Jiang, W. Deposit date: 2015-12-13 Release date: 2016-02-03 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: 2.9 angstrom Resolution Cryo-EM 3D Reconstruction of Close-Packed Virus Particles. Structure, 24, 2016
2MXG	NMR resolved structure of VG16KRKP, an antimicrobial peptide in D8PG micelles Descriptor: antimicrobial peptide Authors: Bhunia, A, Datta, A. Deposit date: 2015-01-01 Release date: 2015-02-04 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: De-novo design of antimicrobial peptides:insights into membrane permeabilisation, lipopolysachharide fragmentation and application in plant disease control To be Published
6NY8	Crystal structure of computationally designed protein XAA_GVDQ with calcium Descriptor: CALCIUM ION, CHLORIDE ION, Design construct XAA_GVDQ Authors: Wei, K.Y, Bick, M.J. Deposit date: 2019-02-11 Release date: 2020-04-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proc.Natl.Acad.Sci.USA, 117, 2020
6NYE	Crystal structure of computationally designed protein XAX Descriptor: Design construct XAX Authors: Wei, K.Y, Bick, M.J. Deposit date: 2019-02-11 Release date: 2020-04-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proc.Natl.Acad.Sci.USA, 117, 2020
6NZ1	Crystal structure of computationally designed protein XXA_GVDQ Descriptor: Design construct XXA_GVDQ Authors: Wei, K.Y, Bick, M.J. Deposit date: 2019-02-12 Release date: 2020-04-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proc.Natl.Acad.Sci.USA, 117, 2020
6NLA	Crystal structure of de novo designed metal-controlled dimer of B1 immunoglobulin-binding domain of Streptococcal Protein G (L12H, E15V, T16L, T18I, V29H, Y33H, N37L)-zinc Descriptor: CHLORIDE ION, GLYCEROL, Immunoglobulin G-binding protein G, ... Authors: Maniaci, B, Stec, B, Huxford, T. Deposit date: 2019-01-08 Release date: 2019-01-23 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Design of High-Affinity Metal-Controlled Protein Dimers. Biochemistry, 58, 2019
6NXM	Crystal structure of computationally designed protein XAA_GVDQ Descriptor: Design construct XAA_GVDQ Authors: Wei, K.Y, Bick, M.J. Deposit date: 2019-02-08 Release date: 2020-04-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proc.Natl.Acad.Sci.USA, 117, 2020

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