4ADP
HCV-J6 NS5B POLYMERASE V405I MUTANT
Summary for 4ADP
Entry DOI | 10.2210/pdb4adp/pdb |
Descriptor | RNA-DIRECTED RNA POLYMERASE (2 entities in total) |
Functional Keywords | hepacivirus, nonstructural proteins, replication, transferase, rna-directed rna polymerase, rdrp, de novo initiation, priming |
Biological source | HEPATITIS C VIRUS (HCV) |
Total number of polymer chains | 1 |
Total formula weight | 64579.09 |
Authors | Scrima, N.,Bressanelli, S. (deposition date: 2012-01-02, release date: 2012-05-02, Last modification date: 2023-12-20) |
Primary citation | Scrima, N.,Caillet-Saguy, C.,Ventura, M.,Harrus, D.,Astier-Gin, T.,Bressanelli, S. Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405. J.Virol., 86:7107-, 2012 Cited by PubMed: 22532694DOI: 10.1128/JVI.00459-12 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.902 Å) |
Structure validation
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