3JYY
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![BU of 3jyy by Molmil](/molmil-images/mine/3jyy) | SeMet LinB complexed with PPi | Descriptor: | Lincosamide nucleotidyltransferase, MAGNESIUM ION, PYROPHOSPHATE | Authors: | Morar, M, Wright, G.D. | Deposit date: | 2009-09-22 | Release date: | 2009-11-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB. Structure, 17, 2009
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3KR7
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![BU of 3kr7 by Molmil](/molmil-images/mine/3kr7) | Human tankyrase 2 - catalytic PARP domain | Descriptor: | GLYCEROL, SULFATE ION, Tankyrase-2, ... | Authors: | Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-18 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. J.Med.Chem., 53, 2010
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7AOP
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![BU of 7aop by Molmil](/molmil-images/mine/7aop) | Structure of NUDT15 in complex with inhibitor TH8321 | Descriptor: | 2-azanyl-9-cyclohexyl-8-(2-methoxyphenyl)-3~{H}-purine-6-thione, MAGNESIUM ION, Nucleotide triphosphate diphosphatase NUDT15 | Authors: | Rehling, D, Zhang, S.M, Helleday, T, Stenmark, P. | Deposit date: | 2020-10-14 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir. Cell Chem Biol, 28, 2021
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7AOM
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![BU of 7aom by Molmil](/molmil-images/mine/7aom) | Structure of NUDT15 in complex with Ganciclovir triphosphate | Descriptor: | Ganciclovir triphosphate, MAGNESIUM ION, Nucleotide triphosphate diphosphatase NUDT15 | Authors: | Rehling, D, Zhang, S.M, Helleday, T, Stenmark, P. | Deposit date: | 2020-10-14 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir. Cell Chem Biol, 28, 2021
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3KR8
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![BU of 3kr8 by Molmil](/molmil-images/mine/3kr8) | Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939 | Descriptor: | 2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol, GLYCEROL, SULFATE ION, ... | Authors: | Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-18 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. J.Med.Chem., 53, 2010
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4IOX
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![BU of 4iox by Molmil](/molmil-images/mine/4iox) | The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | Authors: | Selvarajan Sigamani, S, Zhao, H, Kamau, Y, Tang, L. | Deposit date: | 2013-01-08 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.458 Å) | Cite: | The Structure of the Herpes Simplex Virus DNA-Packaging Terminase pUL15 Nuclease Domain Suggests an Evolutionary Lineage among Eukaryotic and Prokaryotic Viruses. J.Virol., 87, 2013
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2KWQ
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![BU of 2kwq by Molmil](/molmil-images/mine/2kwq) | Mcm10 C-terminal DNA binding domain | Descriptor: | Protein MCM10 homolog, ZINC ION | Authors: | Robertson, P.D, Chagot, B, Chazin, W.J, Eichman, B.F. | Deposit date: | 2010-04-15 | Release date: | 2010-05-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif. J.Biol.Chem., 285, 2010
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2OD8
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![BU of 2od8 by Molmil](/molmil-images/mine/2od8) | Structure of a peptide derived from Cdc9 bound to PCNA | Descriptor: | DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen | Authors: | Chapados, B.R, Tainer, J.A. | Deposit date: | 2006-12-21 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res., 35, 2007
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