8TZZ
 
 | | SpG Cas9 with NGC PAM DNA target | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | | Authors: | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | | Deposit date: | 2023-08-28 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T78
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6O
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 0 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-16 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6Y
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6T
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 13 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-18 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T7S
 | | SpRYmer bound to NAC PAM DNA | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-21 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6S
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 10 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-18 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T6X
 | | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T77
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 6 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-19 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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8T79
 | | SpRY-Cas9:gRNA complex bound to non-target DNA with 10 bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | Authors: | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | | Deposit date: | 2023-06-20 | | Release date: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
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2BRW
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1LM6
 | | Crystal Structure of Peptide Deformylase from Streptococcus pneumoniae | | Descriptor: | FE (III) ION, GLYCEROL, peptide deformylase DEFB | | Authors: | Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A. | | Deposit date: | 2002-04-30 | | Release date: | 2003-06-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
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5F9R
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1JCM
 | | TRPC STABILITY MUTANT CONTAINING AN ENGINEERED DISULPHIDE BRIDGE AND IN COMPLEX WITH A CDRP-RELATED SUBSTRATE | | Descriptor: | 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE, PHOSPHATE ION | | Authors: | Ivens, A, Mayans, O, Szadkowski, H, Wilmanns, M, Kirschner, K. | | Deposit date: | 2001-06-10 | | Release date: | 2002-06-10 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Stabilization of a (betaalpha)8-barrel protein by an engineered disulfide bridge.
Eur.J.Biochem., 269, 2002
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5J5Q
 | | AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type II | | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*GP*C)-3'), DNA topoisomerase 4 subunit B, MAGNESIUM ION, ... | | Authors: | Laponogov, I, Pan, X.-S, Skamrova, G, Umrekar, T, Fisher, L.M, Sanderson, M.R. | | Deposit date: | 2016-04-03 | | Release date: | 2017-07-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase.
Nat Commun, 9, 2018
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1OJN
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1OJP
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1OJM
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2AWA
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1OJO
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1QXO
 | | Crystal structure of Chorismate synthase complexed with oxidized FMN and EPSP | | Descriptor: | 1,2-ETHANEDIOL, 5-[(1-CARBOXYVINYL)OXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, COBALT HEXAMMINE(III), ... | | Authors: | Maclean, J, Ali, S. | | Deposit date: | 2003-09-08 | | Release date: | 2003-12-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structure of chorismate synthase reveals a novel flavin binding site fundamental to a unique chemical reaction
Structure, 11, 2003
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2WJD
 | | Crystal structure of the tyrosine phosphatase Cps4B from Steptococcus pneumoniae TIGR4. | | Descriptor: | MANGANESE (II) ION, SAMARIUM (III) ION, SULFATE ION, ... | | Authors: | Hagelueken, G, Huang, H, Naismith, J.H. | | Deposit date: | 2009-05-25 | | Release date: | 2009-07-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.799 Å) | | Cite: | Crystal Structures of Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly.
J.Mol.Biol., 392, 2009
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1QJL
 | | METALLOTHIONEIN MTA FROM SEA URCHIN (BETA DOMAIN) | | Descriptor: | CADMIUM ION, METALLOTHIONEIN | | Authors: | Riek, R, Precheur, B, Wang, Y, Mackay, E.A, Wider, G, Guntert, P, Liu, A, Kaegi, J.H.R, Wuthrich, K. | | Deposit date: | 1999-06-24 | | Release date: | 1999-08-31 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA.
J. Mol. Biol., 291, 1999
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1QJK
 | | Metallothionein MTA from sea urchin (alpha domain) | | Descriptor: | CADMIUM ION, METALLOTHIONEIN | | Authors: | Riek, R, Precheur, B, Wang, Y, Mackay, E.A, Wider, G, Guntert, P, Liu, A, Kaegi, J.H.R, Wuthrich, K. | | Deposit date: | 1999-06-24 | | Release date: | 1999-08-31 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA.
J. Mol. Biol., 291, 1999
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2VW2
 | | Crystal structure of the NanB sialidase from Streptococcus pneumoniae | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SIALIDASE B | | Authors: | Xu, G, Potter, J.A, Russell, R.J.M, Oggioni, M.R, Andrew, P.W, Taylor, G.L. | | Deposit date: | 2008-06-13 | | Release date: | 2008-06-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae
J.Mol.Biol., 384, 2008
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