7P9I
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![BU of 7p9i by Molmil](/molmil-images/mine/7p9i) | Structure of E.coli RlmJ in complex with an RNA conjugate (GAA-SAM) | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GAA-SAM), Ribosomal RNA large subunit methyltransferase J | Authors: | Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. | Deposit date: | 2021-07-27 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.594 Å) | Cite: | Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
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7PAX
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![BU of 7pax by Molmil](/molmil-images/mine/7pax) | Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium, FsPP and IPP | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, ... | Authors: | Giladi, M, Lisnyansky Bar-El, M, Haitin, Y. | Deposit date: | 2021-07-30 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases. Sci Adv, 8, 2022
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7PB1
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![BU of 7pb1 by Molmil](/molmil-images/mine/7pb1) | Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium, GGPP and IsPP | Descriptor: | 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, ... | Authors: | Giladi, M, Lisnyansky Bar-El, M, Haitin, Y. | Deposit date: | 2021-07-30 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases. Sci Adv, 8, 2022
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7PB0
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![BU of 7pb0 by Molmil](/molmil-images/mine/7pb0) | Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium, GGsPP and IsPP | Descriptor: | 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, ... | Authors: | Giladi, M, Lisnyansky Bar-El, M, Haitin, Y. | Deposit date: | 2021-07-30 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases. Sci Adv, 8, 2022
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7OOT
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![BU of 7oot by Molmil](/molmil-images/mine/7oot) | X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element | Descriptor: | DNA (5'-D(P*AP*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3'), DNA (5'-D(P*TP*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3'), Interferon regulatory factor 4, ... | Authors: | Agnarelli, A, El Omari, K, Alt, A.O, Mancini, E.J. | Deposit date: | 2021-05-28 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to interferon-stimulated response element To Be Published
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7P1N
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![BU of 7p1n by Molmil](/molmil-images/mine/7p1n) | Crystal structure of human acetylcholinesterase in complex with (2R,3R,4S,5S,6R)-2-{4-[1-(4-{5-hydroxy-6-[(E)-(hydroxyimino)methyl]pyridin-2-yl}butyl)-1H-1,2,3-triazol-4-yl]butoxy}-6-(hydroxymethyl)oxane-3,4,5-triol oxime | Descriptor: | (2R,3R,4S,5S,6R)-2-[4-[1-[4-[6-[(Z)-hydroxyiminomethyl]-5-oxidanyl-pyridin-2-yl]butyl]-1,2,3-triazol-4-yl]butoxy]-6-(hydroxymethyl)oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | Authors: | Da Silva, O, Dias, J, Nachon, F. | Deposit date: | 2021-07-02 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning. J.Med.Chem., 65, 2022
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3OJY
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![BU of 3ojy by Molmil](/molmil-images/mine/3ojy) | Crystal Structure of Human Complement Component C8 | Descriptor: | CALCIUM ION, Complement component C8 alpha chain, Complement component C8 beta chain, ... | Authors: | Lovelace, L.L, Cooper, C.L, Sodetz, J.M, Lebioda, L. | Deposit date: | 2010-08-23 | Release date: | 2011-04-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement. J.Biol.Chem., 286, 2011
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7OPT
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![BU of 7opt by Molmil](/molmil-images/mine/7opt) | Crystal structure of Trypanosoma cruzi peroxidase | Descriptor: | Ascorbate peroxidase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | Deposit date: | 2021-06-01 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate. J.Biol.Chem., 298, 2022
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3TLS
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![BU of 3tls by Molmil](/molmil-images/mine/3tls) | The GLIC pentameric Ligand-Gated Ion Channel E19'P mutant in a locally-closed conformation (LC2 subtype) | Descriptor: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | Authors: | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | Deposit date: | 2011-08-30 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
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7OSH
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![BU of 7osh by Molmil](/molmil-images/mine/7osh) | ABC Transporter complex NosDFYL, R-domain 2 | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | Deposit date: | 2021-06-08 | Release date: | 2022-06-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSJ
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![BU of 7osj by Molmil](/molmil-images/mine/7osj) | ABC Transporter complex NosDFYL, membrane anchor | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | Deposit date: | 2021-06-08 | Release date: | 2022-06-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSG
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![BU of 7osg by Molmil](/molmil-images/mine/7osg) | ABC Transporter complex NosDFYL, consensus refinement | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | Deposit date: | 2021-06-08 | Release date: | 2022-06-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSI
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![BU of 7osi by Molmil](/molmil-images/mine/7osi) | ABC Transporter complex NosDFYL, R-domain 3 | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | Deposit date: | 2021-06-08 | Release date: | 2022-06-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSF
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![BU of 7osf by Molmil](/molmil-images/mine/7osf) | ABC Transporter complex NosDFYL, R-domain 1 | Descriptor: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | Deposit date: | 2021-06-08 | Release date: | 2022-06-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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3TXT
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![BU of 3txt by Molmil](/molmil-images/mine/3txt) | Crystal structure of GlpG in complex with inhibitor DFP | Descriptor: | DIISOPROPYL PHOSPHONATE, Rhomboid protease glpG | Authors: | Xue, Y, Ha, Y. | Deposit date: | 2011-09-23 | Release date: | 2011-12-07 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of rhomboid protease GlpG in complex with a mechanism-based inhibitor To be Published
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7OQR
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![BU of 7oqr by Molmil](/molmil-images/mine/7oqr) | Crystal structure of Trypanosoma cruzi peroxidase | Descriptor: | ACETATE ION, Ascorbate peroxidase, GLYCEROL, ... | Authors: | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | Deposit date: | 2021-06-04 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate. J.Biol.Chem., 298, 2022
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7OUE
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![BU of 7oue by Molmil](/molmil-images/mine/7oue) | Crystal structure of a trapped Pab-AGOG/single-standed DNA covalent intermediate | Descriptor: | DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), N-glycosylase/DNA lyase, PHOSPHATE ION, ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-06-11 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7P63
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![BU of 7p63 by Molmil](/molmil-images/mine/7p63) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Closed state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P62
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![BU of 7p62 by Molmil](/molmil-images/mine/7p62) | Complex I from E. coli, DDM-purified, Apo, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P69
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![BU of 7p69 by Molmil](/molmil-images/mine/7p69) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P61
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![BU of 7p61 by Molmil](/molmil-images/mine/7p61) | Complex I from E. coli, DDM-purified, with NADH, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7L
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![BU of 7p7l by Molmil](/molmil-images/mine/7p7l) | Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P64
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![BU of 7p64 by Molmil](/molmil-images/mine/7p64) | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-15 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7C
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![BU of 7p7c by Molmil](/molmil-images/mine/7p7c) | Complex I from E. coli, DDM/LMNG-purified, Apo, Open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7E
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![BU of 7p7e by Molmil](/molmil-images/mine/7p7e) | Complex I from E. coli, DDM/LMNG-purified, Apo, Resting state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | Authors: | Kravchuk, V, Kampjut, D, Sazanov, L. | Deposit date: | 2021-07-19 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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