PDB: 125 resultsInfo pagesStatus searchChemie searchBIRD

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4N97	E. coli sliding clamp in complex with 5-nitroindole Descriptor: 5-nitro-1H-indole, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N99	E. coli sliding clamp in complex with 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid Descriptor: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
6AP4	Crystal structure of the DNA polymerase III subunit beta from Acinetobacter baumannii Descriptor: DNA polymerase III subunit beta, MAGNESIUM ION Authors: McGrath, A.E, Oakley, A.J. Deposit date: 2017-08-16 Release date: 2017-12-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. J. Struct. Biol., 204, 2018
6AMS	Crystal structure of the DNA polymerase III subunit beta from Pseudomonas aeruginosa Descriptor: Beta sliding clamp, PHOSPHATE ION Authors: McGrath, A.E, Oakley, A.J. Deposit date: 2017-08-11 Release date: 2017-11-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. J. Struct. Biol., 204, 2018
6AMQ	Crystal structure of the DNA polymerase III subunit beta from Enterobacter cloacae Descriptor: DNA polymerase III subunit beta, SULFATE ION Authors: McGrath, A.E, Oakley, A.J. Deposit date: 2017-08-11 Release date: 2017-11-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. J. Struct. Biol., 204, 2018
6DJK	Structure of DNA polymerase III subunit beta from Rickettsia typhi in complex with a natural product Descriptor: 1,2-ETHANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-05-25 Release date: 2019-05-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structure of DNA polymerase III subunit beta from Rickettsia typhi in complex with a natural product to be published
6D46	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Rickettsia typhi str. Wilmington Descriptor: Beta sliding clamp, CHLORIDE ION, TETRAETHYLENE GLYCOL Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-04-17 Release date: 2018-05-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Rickettsia typhi str. Wilmington To Be Published
6DEG	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 Descriptor: Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-05-11 Release date: 2018-05-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 To Be Published
6D47	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum Descriptor: Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-04-17 Release date: 2018-05-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum To Be Published
6DJ8	Structure of DNA polymerase III subunit beta from Borrelia burgdorferi in complex with a natural product Descriptor: Beta sliding clamp, Natural product peptide Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-05-24 Release date: 2019-05-29 Last modified: 2019-07-17 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of DNA polymerase III subunit beta from Borrelia burgdorferi in complex with a natural product to be published
6DLK	Crystal structure of DNA polymerase III subunit beta from Rickettsia rickettsii Descriptor: 1,2-ETHANEDIOL, Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-06-01 Release date: 2018-10-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of DNA polymerase III subunit beta from Rickettsia rickettsii to be published
6DLY	Crystal structure of DNA polymerase III subunit beta from Mycobacterium marinum in complex with a natural product Descriptor: 1,2-ETHANEDIOL, Beta sliding clamp, Natural product peptide Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-06-04 Release date: 2019-06-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of DNA polymerase III subunit beta from Mycobacterium marinum in complex with a natural product to be published
6DM6	Structure of DNA polymerase III subunit beta from Rickettsia conorii in complex with a natural product Descriptor: Beta sliding clamp, Natural product peptide Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-06-04 Release date: 2019-06-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure of DNA polymerase III subunit beta from Rickettsia conorii in complex with a natural product to be published
7AZ6	DNA polymerase sliding clamp from Escherichia coli with peptide 36 bound Descriptor: ACETATE ION, Beta sliding clamp, CHLORIDE ION, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZD	DNA polymerase sliding clamp from Escherichia coli with peptide 20 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZ7	DNA polymerase sliding clamp from Escherichia coli with peptide 37 bound Descriptor: Beta sliding clamp, FORMIC ACID, PENTAETHYLENE GLYCOL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZE	DNA polymerase sliding clamp from Escherichia coli with peptide 18 bound Descriptor: Beta sliding clamp, GLYCEROL, MALONATE ION, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZK	DNA polymerase sliding clamp from Escherichia coli with peptide 35 bound Descriptor: Beta sliding clamp, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZ5	DNA polymerase sliding clamp from Escherichia coli with peptide 47 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, Peptide 47, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZG	DNA polymerase sliding clamp from Escherichia coli with peptide 4 bound Descriptor: Beta sliding clamp, Peptide 4 Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZF	DNA polymerase sliding clamp from Escherichia coli with peptide 8 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZ8	DNA polymerase sliding clamp from Escherichia coli with peptide 43 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZL	DNA polymerase sliding clamp from Escherichia coli with peptide 38 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZC	DNA polymerase sliding clamp from Escherichia coli with peptide 22 bound Descriptor: Beta sliding clamp, GLYCEROL, Peptide 22 Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7EVP	Cryo-EM structure of the Gp168-beta-clamp complex Descriptor: Beta sliding clamp, Sliding clamp inhibitor Authors: Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. Deposit date: 2021-05-21 Release date: 2022-02-16 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel. Nucleic Acids Res., 49, 2021

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