1A7A
| STRUCTURE OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE: DETERMINATION OF A 30 SELENIUM ATOM SUBSTRUCTURE FROM DATA AT A SINGLE WAVELENGTH | Descriptor: | (1'R,2'S)-9-(2-HYDROXY-3'-KETO-CYCLOPENTEN-1-YL)ADENINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-ADENOSYLHOMOCYSTEINE HYDROLASE | Authors: | Turner, M.A, Yuan, C.-S, Borchardt, R.T, Hershfield, M.S, Smith, G.D, Howell, P.L. | Deposit date: | 1998-03-10 | Release date: | 1999-04-20 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength. Nat.Struct.Biol., 5, 1998
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1B3R
| RAT LIVER S-ADENOSYLHOMOCYSTEIN HYDROLASE | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (S-ADENOSYLHOMOCYSTEINE HYDROLASE) | Authors: | Hu, Y, Komoto, J, Huang, Y, Takusagawa, F, Gomi, T, Ogawa, H, Takata, Y, Fujioka, M. | Deposit date: | 1998-12-14 | Release date: | 1998-12-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of S-adenosylhomocysteine hydrolase from rat liver. Biochemistry, 38, 1999
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2H5L
| S-Adenosylhomocysteine hydrolase containing NAD and 3-deaza-D-eritadenine | Descriptor: | (2R,3R)-4-(4-AMINO-1H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-2,3-DIHYDROXYBUTANOIC ACID, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Yamada, T, Komoto, J, Takusagawa, F. | Deposit date: | 2006-05-26 | Release date: | 2007-04-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and function of eritadenine and its 3-deaza analogues: Potent inhibitors of S-adenosylhomocysteine hydrolase and hypocholesterolemic agents. Biochem.Pharm., 73, 2007
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1KY5
| D244E mutant S-Adenosylhomocysteine hydrolase refined with noncrystallographic restraints | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3'-OXO-ADENOSINE, S-adenosylhomocysteine hydrolase | Authors: | Takata, Y, Takusagawa, F. | Deposit date: | 2002-02-03 | Release date: | 2002-09-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Catalytic Mechanism of S-adenosylhomocysteine hydrolase. Site-directed
mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190. J.Biol.Chem., 277, 2002
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1XWF
| K185N mutated S-adenosylhomocysteine hydrolase | Descriptor: | ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Yamada, T, Takata, Y, Komoto, J, Gomi, T, Ogawa, H, Fujioka, M, Takusagawa, F. | Deposit date: | 2004-11-01 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Catalytic mechanism of S-adenosylhomocysteine hydrolase: Roles of His 54, Asp130, Glu155, Lys185, and Aspl89. Int.J.Biochem.Cell Biol., 37, 2005
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5HM8
| 2.85 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Adenosine and NAD. | Descriptor: | ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ... | Authors: | Minasov, G, Shuvalova, L, Halavaty, A, Kiryukhina, O, Dubrovska, I, Bishop, B, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-01-15 | Release date: | 2016-01-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | 2.85 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Adenosine and NAD. To Be Published
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3X2E
| A thermophilic hydrolase | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Adenosylhomocysteinase | Authors: | Zheng, Y, Ko, T.P, Huang, C.H. | Deposit date: | 2014-12-21 | Release date: | 2015-05-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritima. J.Struct.Biol., 190, 2015
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1K0U
| Inhibition of S-adenosylhomocysteine Hydrolase by "acyclic sugar" Adenosine Analogue D-eritadenine | Descriptor: | D-ERITADENINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE | Authors: | Takusagawa, F, Huang, Y, Komoto, J, Takata, Y, Gomi, T, Ogawa, H, Fujioka, M, Powell, D. | Deposit date: | 2001-09-20 | Release date: | 2001-10-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine. J.Biol.Chem., 277, 2002
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