1XWF

K185N mutated S-adenosylhomocysteine hydrolase

Summary for 1XWF

Entry DOI	10.2210/pdb1xwf/pdb
Descriptor	Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENOSINE, ... (4 entities in total)
Functional Keywords	s-adenosylhomocysteine hydrolase, adohcy hydrolase, adohcyase, sahh, hydrolase
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Cytoplasm: P10760
Total number of polymer chains	4
Total formula weight	193525.20
Authors	Yamada, T.,Takata, Y.,Komoto, J.,Gomi, T.,Ogawa, H.,Fujioka, M.,Takusagawa, F. (deposition date: 2004-11-01, release date: 2005-09-20, Last modification date: 2024-02-14)
Primary citation	Yamada, T.,Takata, Y.,Komoto, J.,Gomi, T.,Ogawa, H.,Fujioka, M.,Takusagawa, F. Catalytic mechanism of S-adenosylhomocysteine hydrolase: Roles of His 54, Asp130, Glu155, Lys185, and Aspl89. Int.J.Biochem.Cell Biol., 37:2417-2435, 2005 Cited by PubMed: 16061414 DOI: 10.1016/j.biocel.2005.06.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation