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5W0H
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BU of 5w0h by Molmil
Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
5EN1
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BU of 5en1 by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2015-11-09
Release date:2016-11-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1
Nat Commun, 2018
5GVQ
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BU of 5gvq by Molmil
Solution structure of the first RRM domain of human spliceosomal protein SF3b49
Descriptor: Splicing factor 3B subunit 4
Authors:Kuwasako, K, Nameki, N, Tsuda, K, Takahashi, M, Sato, A, Tochio, N, Inoue, M, Terada, T, Kigawa, T, Kobayashi, N, Shirouzu, M, Ito, T, Sakamoto, T, Wakamatsu, K, Guntert, P, Takahashi, S, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2016-09-06
Release date:2017-04-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment.
Protein Sci., 26, 2017
6Q2I
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BU of 6q2i by Molmil
Solution state NMR structures of the RNA recognition motif (RRM) domain of human CstF-64
Descriptor: Cleavage stimulation factor subunit 2
Authors:Latham, M.P, Masoumzadeh, E.
Deposit date:2019-08-08
Release date:2020-08-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans.
Nucleic Acids Res., 48, 2020
5D77
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BU of 5d77 by Molmil
Structure of Mip6 RRM3 Domain
Descriptor: CITRIC ACID, NITRATE ION, RNA-binding protein MIP6, ...
Authors:Mohamad, N, Bravo, J.
Deposit date:2015-08-13
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of Mip6 RRM3 domain at 1.3
To Be Published
5DDP
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BU of 5ddp by Molmil
L-glutamine riboswitch bound with L-glutamine
Descriptor: GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ...
Authors:Ren, A, Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DET
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BU of 5det by Molmil
X-ray structure of human RBPMS in complex with the RNA
Descriptor: RNA (5'-R(*UP*CP*AP*C)-3'), RNA (5'-R(P*UP*CP*AP*CP*U)-3'), RNA-binding protein with multiple splicing, ...
Authors:Teplova, M, Farazi, T.A, Tuschl, T, Patel, D.J.
Deposit date:2015-08-25
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS.
Q. Rev. Biophys., 49, 2016
5CYJ
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BU of 5cyj by Molmil
X-ray structure of human RBPMS
Descriptor: RNA-binding protein with multiple splicing
Authors:Teplova, M, Farazi, T.A, Patel, D.J.
Deposit date:2015-07-30
Release date:2015-09-30
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS.
Q. Rev. Biophys., 49, 2016
5D78
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BU of 5d78 by Molmil
Structure of RRM3 Domain of Mip6 at 1.25 A Resolution
Descriptor: BETA-MERCAPTOETHANOL, RNA-binding protein MIP6, SULFATE ION
Authors:Mohamad, N, Bravo, J.
Deposit date:2015-08-13
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.251 Å)
Cite:Structure of RRM3 Domain of Mip6 at 1.25 A Resolution
To Be Published
5DDQ
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BU of 5ddq by Molmil
L-glutamine riboswitch bound with L-glutamine soaked with Mn2+
Descriptor: GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ...
Authors:Ren, A, Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5DDR
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BU of 5ddr by Molmil
L-glutamine riboswitch bound with L-glutamine soaked with Cs+
Descriptor: CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ...
Authors:Ren, A, Patel, D.J.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5EV1
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BU of 5ev1 by Molmil
Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.037 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5EV2
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BU of 5ev2 by Molmil
Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal
Descriptor: 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5EV3
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BU of 5ev3 by Molmil
Structure III of Intact U2AF65 Recognizing the 3' Splice Site Signal
Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU)P*UP*U)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5EV4
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BU of 5ev4 by Molmil
Structure IV of Intact U2AF65 Recognizing the 3' Splice Site Signal
Descriptor: DNA/RNA (5'-R(P*UP*UP*UP*(UD)P*UP*U)-D(P*(BRU)P*(UD))-R(P*C)-3'), GLYCEROL, Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016
5DDO
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BU of 5ddo by Molmil
Structural and Dynamic Basis for Low Affinity-High Selectivity Binding of L-glutamine by the Gln-riboswitch
Descriptor: L-glutamine riboswitch (58-MER), U1 small nuclear ribonucleoprotein A
Authors:Ren, A, Patel, D.
Deposit date:2015-08-25
Release date:2015-12-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
5BJR
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BU of 5bjr by Molmil
Crystal structure of the N-terminal RRM domain from MEC-8
Descriptor: AMMONIUM ION, Mec-8 protein
Authors:Soufari, H, Mackereth, C.D.
Deposit date:2016-10-22
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
5HO4
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BU of 5ho4 by Molmil
Crystal structure of hnRNPA2B1 in complex with 10-mer RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3')
Authors:Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B.
Deposit date:2016-01-19
Release date:2017-02-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
2YWK
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BU of 2ywk by Molmil
Crystal structure of RRM-domain derived from human putative RNA-binding protein 11
Descriptor: Putative RNA-binding protein 11
Authors:Kawazoe, M, Takemoto, C, Kaminishi, T, Uchikubo-Kamo, T, Nishino, A, Morita, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-20
Release date:2008-04-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal structure of RRM-domain derived from human putative RNA-binding protein 11
To be Published
7ZIR
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BU of 7zir by Molmil
Cryo-EM structure of hnRNPDL amyloid fibrils
Descriptor: Heterogeneous nuclear ribonucleoprotein D-like
Authors:Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S.
Deposit date:2022-04-08
Release date:2022-12-28
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3.
Nat Commun, 14, 2023
2YTC
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BU of 2ytc by Molmil
Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22
Descriptor: Pre-mRNA-splicing factor RBM22
Authors:Kasahara, N, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2007-10-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22
To be Published
7ZUG
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BU of 7zug by Molmil
Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain
Descriptor: CHLORIDE ION, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed, ...
Authors:Winter, N, Kumar, M, Isupov, M.N, Wiener, R.
Deposit date:2022-05-12
Release date:2023-05-24
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.075 Å)
Cite:Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain
To Be Published
4Y00
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BU of 4y00 by Molmil
Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA
Descriptor: DNA (5'-D(P*TP*TP*GP*AP*GP*CP*GP*T)-3'), TAR DNA-binding protein 43
Authors:Chiang, C.H, Kuo, P.H, Yang, W.Z, Yuan, H.S.
Deposit date:2015-02-05
Release date:2016-02-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Sci Rep, 6, 2016
4Y0F
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BU of 4y0f by Molmil
Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA
Descriptor: DNA (5'-D(*GP*TP*TP*GP*AP*GP*CP*GP*TP*T)-3'), TAR DNA-binding protein 43
Authors:Chiang, C.H, Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yuan, H.S.
Deposit date:2015-02-06
Release date:2016-02-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
Sci Rep, 6, 2016
6CMN
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BU of 6cmn by Molmil
Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7
Descriptor: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element
Authors:Belashov, I.A, Wedekind, J.E.
Deposit date:2018-03-05
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription.
Nucleic Acids Res., 46, 2018

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數據於2024-07-17公開中

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