2GST
 
 | | STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE | | Descriptor: | GLUTATHIONE S-TRANSFERASE, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, SULFATE ION | | Authors: | Ji, X, Armstrong, R.N, Gilliland, G.L. | | Deposit date: | 1993-06-07 | | Release date: | 1993-10-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.
Biochemistry, 33, 1994
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2VCV
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2X64
 | | GLUTATHIONE-S-TRANSFERASE FROM XYLELLA FASTIDIOSA | | Descriptor: | CHLORIDE ION, GLUTATHIONE, GLUTATHIONE-S-TRANSFERASE | | Authors: | Muniz, J.R.C, Rodrigues, N.C, Bleicher, L, Travensolo, R.F, Garcia, W. | | Deposit date: | 2010-02-14 | | Release date: | 2010-03-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Biophysical Characterization of the Recombinant Glutathione-S-Transferase from Xylella
To be Published
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3GUR
 | | Crystal Structure of mu class glutathione S-transferase (GSTM2-2) in complex with glutathione and 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) | | Descriptor: | 1,2-ETHANEDIOL, GLUTATHIONE, Glutathione S-transferase Mu 2, ... | | Authors: | Federici, L, Lo Sterzo, C, Di Matteo, A, Scaloni, F, Federici, G, Caccuri, A.M. | | Deposit date: | 2009-03-30 | | Release date: | 2009-10-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases
Cancer Res., 69, 2009
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4BVY
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6EP6
 | | ARABIDOPSIS THALIANA GSTU23, reduced | | Descriptor: | GLYCEROL, Glutathione S-transferase U23, MAGNESIUM ION | | Authors: | Tossounian, M.A, Van Molle, I, Wahni, K, Jacques, S, Vertommen, D, Gevaert, K, Van Breusegem, F, Young, D, Rosado, L, Messens, J. | | Deposit date: | 2017-10-10 | | Release date: | 2018-04-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.592 Å) | | Cite: | Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.
Biochim. Biophys. Acta, 1862, 2018
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4BVX
 | | Crystal structure of the AIMP3-MRS N-terminal domain complex with I3C | | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, METHIONINE--TRNA LIGASE, ... | | Authors: | Cho, H.Y, Seo, W.W, Cho, H.J, Kang, B.S. | | Deposit date: | 2013-06-29 | | Release date: | 2014-07-16 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Assembly of Multi-tRNA Synthetase Complex Via Heterotetrameric Glutathione Transferase-Homology Domains.
J.Biol.Chem., 290, 2015
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3U6V
 | | Crystal Structure Analysis of L23A mutant of human GST A1-1 | | Descriptor: | Glutathione S-transferase A1 | | Authors: | Fanucchi, S, Achilonu, I.A, Khoza, T.N, Fernandes, M.A, Gildenhuys, S, Dirr, H.W. | | Deposit date: | 2011-10-13 | | Release date: | 2011-10-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure Analysis of L23A mutant of human GST A1-1
To be Published
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4ACS
 | | Crystal structure of mutant GST A2-2 with enhanced catalytic efficiency with azathioprine | | Descriptor: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE A2 | | Authors: | Zhang, W, Moden, O, Tars, K, Mannervik, B. | | Deposit date: | 2011-12-19 | | Release date: | 2011-12-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine.
Chem.Biol., 19, 2012
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3UAR
 | | Crystal structure of glutathione transferase (TARGET EFI-501774) from methylococcus capsulatus str. bath with gsh bound | | Descriptor: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase | | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | Deposit date: | 2011-10-21 | | Release date: | 2011-11-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of Glutathione S-Transferase from Methylococcus Capsulatus
To be Published
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6EP7
 | | ARABIDOPSIS THALIANA GSTU23, GSH bound | | Descriptor: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase U23, ... | | Authors: | Tossounian, M.A, Van Molle, I, Wahni, K, Jacques, S, Vertommen, D, Gevaert, K, Van Breusegem, F, Young, D, Rosado, L, Messens, J. | | Deposit date: | 2017-10-11 | | Release date: | 2018-04-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.947 Å) | | Cite: | Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.
Biochim. Biophys. Acta, 1862, 2018
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6EZY
 | | ARABIDOPSIS THALIANA GSTF9, GSH AND GSOH BOUND | | Descriptor: | BROMIDE ION, GLUTATHIONE, GLYCEROL, ... | | Authors: | Tossounian, M.A, Wahni, K, VanMolle, I, Rosado, L, Vertommen, D, Messens, J. | | Deposit date: | 2017-11-16 | | Release date: | 2018-08-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility.
Protein Sci., 28, 2019
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6F01
 | | ARABIDOPSIS THALIANA GSTF9, GSO3 AND GSOH BOUND | | Descriptor: | BROMIDE ION, GLUTATHIONE SULFONIC ACID, GLYCEROL, ... | | Authors: | Tossounian, M.A, Wahni, K, Van Molle, I, Vertommen, D, Rosado, L, Messens, J. | | Deposit date: | 2017-11-17 | | Release date: | 2018-08-15 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility.
Protein Sci., 28, 2019
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3VK9
 | | Crystal structure of delta-class glutathione transferase from silkmoth | | Descriptor: | GLYCEROL, Glutathione S-transferase delta | | Authors: | Kakuta, Y, Usuda, K, Higashiura, A, Suzuki, M, Nakagawa, A, Kimura, M, Yamamoto, K. | | Deposit date: | 2011-11-10 | | Release date: | 2012-10-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Structural basis for catalytic activity of a silkworm Delta-class glutathione transferase
Biochim.Biophys.Acta, 1820, 2012
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6F05
 | | ARABIDOPSIS THALIANA GSTF9, GSO3 BOUND | | Descriptor: | CHLORIDE ION, GLUTATHIONE SULFONIC ACID, GLYCEROL, ... | | Authors: | Tossounian, M.A, Wahni, K, VanMolle, I, Vertommen, D, Rosado, L, Messens, J. | | Deposit date: | 2017-11-17 | | Release date: | 2018-08-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility.
Protein Sci., 28, 2019
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3IBH
 | | Crystal structure of Saccharomyces cerevisiae Gtt2 in complex with glutathione | | Descriptor: | GLUTATHIONE, Saccharomyces cerevisiae Gtt2 | | Authors: | Ma, X.X, Jiang, Y.L, He, Y.X, Bao, R, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2009-07-15 | | Release date: | 2009-10-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family.
Embo Rep., 10, 2009
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3IK9
 | | Human GST A1-1-GIMF with GSDHN | | Descriptor: | (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-((3S,4R)-1,4-dihydroxynonan-3-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid, Glutathione S-transferase A1 | | Authors: | Balogh, L.M, Le Trong, I, Atkins, W.M, Stenkamp, R.E. | | Deposit date: | 2009-08-05 | | Release date: | 2010-06-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Substrate specificity combined with stereopromiscuity in glutathione transferase A4-4-dependent metabolism of 4-hydroxynonenal.
Biochemistry, 49, 2010
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3VWX
 | | Structural analysis of an epsilon-class glutathione S-transferase from housefly, Musca domestica | | Descriptor: | GLUTATHIONE, Glutathione s-transferase 6B | | Authors: | Nakamura, C, Sue, M, Miyamoto, T, Yajima, S. | | Deposit date: | 2012-09-05 | | Release date: | 2013-02-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural analysis of an epsilon-class glutathione transferase from housefly, Musca domestica
Biochem.Biophys.Res.Commun., 430, 2013
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3UAP
 | | Crystal structure of glutathione transferase (TARGET EFI-501774) from methylococcus capsulatus str. bath | | Descriptor: | GLYCEROL, Glutathione S-transferase | | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | Deposit date: | 2011-10-21 | | Release date: | 2011-11-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of Glutathione S-Transferase from Methylococcus Capsulatus
To be Published
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6GSY
 | | FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | | Descriptor: | GLUTATHIONE, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3 | | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | | Deposit date: | 1996-01-26 | | Release date: | 1996-11-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
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3ZFB
 | | Crystal structure of the I75A mutant of human class alpha glutathione transferase in the apo form | | Descriptor: | GLUTATHIONE S-TRANSFERASE A1 | | Authors: | Parbhoo, N, Fanucchi, S, Achilonu, I.A, Fernandes, M.A, Gildenhuys, S, Dirr, H.W. | | Deposit date: | 2012-12-11 | | Release date: | 2012-12-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Crystal Structure of the I75A Mutant of Human Class Alpha Glutathione Transferase in the Apo Form
To be Published
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3ZMK
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6GSV
 | | FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE | | Descriptor: | L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION | | Authors: | Xiao, G, Ji, X, Armstrong, R.N, Gilliland, G.L. | | Deposit date: | 1996-01-26 | | Release date: | 1996-11-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
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3I69
 | | Apo Glutathione Transferase A1-1 GIMF-helix mutant | | Descriptor: | GLUTATHIONE, Glutathione S-transferase A1 | | Authors: | Balogh, L.M, Le Trong, I, Stenkamp, R.E, Atkins, W.M. | | Deposit date: | 2009-07-06 | | Release date: | 2009-09-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Structural analysis of a glutathione transferase A1-1 mutant tailored for high catalytic efficiency with toxic alkenals.
Biochemistry, 48, 2009
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3ZML
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