6EP7

ARABIDOPSIS THALIANA GSTU23, GSH bound

Summary for 6EP7

• Entry DOI: 10.2210/pdb6ep7/pdb
• Related: 5O84 6EP6
• Descriptor: Glutathione S-transferase U23, GLUTATHIONE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: transferase, tau class, peroxidase
• Biological source: Arabidopsis thaliana (Mouse-ear cress)
• Cellular location: Cytoplasm, cytosol : Q9M9F1
• Total number of polymer chains: 2
• Total formula weight: 52432.55

Authors

Tossounian, M.A.,Van Molle, I.,Wahni, K.,Jacques, S.,Vertommen, D.,Gevaert, K.,Van Breusegem, F.,Young, D.,Rosado, L.,Messens, J. (deposition date: 2017-10-11, release date: 2018-04-11, Last modification date: 2024-01-17)

Primary citation

Tossounian, M.A.,Van Molle, I.,Wahni, K.,Jacques, S.,Gevaert, K.,Van Breusegem, F.,Vertommen, D.,Young, D.,Rosado, L.A.,Messens, J.
Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.
Biochim. Biophys. Acta, 1862:775-789, 2018

PubMed Abstract: Glutathione transferases play an important role as detoxifying enzymes. In A. thaliana, elevated levels of reactive oxygen species (ROS), provoked during biotic and abiotic stress, influence the activity of GSTU23. The aim of this study is to determine the impact of oxidative stress on the function and structure of GSTU23.

PubMed: 29031766
DOI: 10.1016/j.bbagen.2017.10.007

Experimental method

X-RAY DIFFRACTION (1.947 Å)