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8K5D
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BU of 8k5d by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Human hydroxycarboxylic acid receptor 2
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5B
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BU of 8k5b by Molmil
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: Human Hydroxycarboxylic acid receptor 2, NICOTINIC ACID
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K53
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BU of 8k53 by Molmil
Structure of the Dimeric Human CNTN2 Ig 1-6-FNIII 1-2 Domain in an Asymmetric State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ...
Authors:Zhang, Z.Z.
Deposit date:2023-07-21
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of human CNTN2 immunoglobulin domains 1-6 homo-dimer
To Be Published
8K4N
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BU of 8k4n by Molmil
Structure of GPR34-Gi complex
Descriptor: (2R)-2-azanyl-3-[oxidanyl-[(2R)-2-oxidanyl-3-tetradec-9-enoyloxy-propoxy]phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wong, T.S, Zeng, Z.C, Xiong, T.T, Gan, S.Y, He, G.D, Du, Y.
Deposit date:2023-07-20
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Cryo-EM structure of GPR34-Gi complex
To Be Published
8K4P
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BU of 8k4p by Molmil
Cryo-EM structure of an active Kaposi's Sarcoma-Associated Herpesvirus-G Protein-Coupled Receptor (KSHV-GPCR) in complex with Gi protein
Descriptor: G protein-coupled receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Liu, Y.Z, Liu, A.J.
Deposit date:2023-07-20
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Cryo-EM structure of active Kaposi's Sarcoma-Associated Herpesvirus-G Protein-Coupled Receptor (KSHV-GPCR) in complex with Gi protein
To Be Published
8K4O
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BU of 8k4o by Molmil
Cryo-EM structure of Kaposi's Sarcoma-Associated Herpesvirus-G Protein-Coupled Receptor (KSHV-GPCR)in complex with CXC chemokine CXCL1
Descriptor: G protein-coupled receptor, Growth-regulated alpha protein, Guanine nucleotide-binding protein G(I) subunit alpha-1, ...
Authors:Liu, Y.Z, Liu, A.J.
Deposit date:2023-07-20
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Cryo-EM structure of Kaposi's Sarcoma Herpesvirus GPCR (KSHV-GPCR)in complex with CXCL1
To Be Published
8PWN
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BU of 8pwn by Molmil
Structure of A2A adenosine receptor A2AR-StaR2-bRIL, solved at wavelength 2.75 A
Descriptor: Adenosine receptor A2a,Soluble cytochrome b562, CHOLESTEROL, OLEIC ACID, ...
Authors:El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Romano, M, Moraes, I, Wagner, A.
Deposit date:2023-07-20
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8TI3
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BU of 8ti3 by Molmil
Yeast actin wild type
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION
Authors:Volkmann, N, Hanein, D.
Deposit date:2023-07-19
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:yeast actin wild type
To Be Published
8PW7
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BU of 8pw7 by Molmil
A respirasome from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-07-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8PW6
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BU of 8pw6 by Molmil
C respirasome from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-07-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8PW5
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BU of 8pw5 by Molmil
CS respirasome from murine liver
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2023-07-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8TID
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BU of 8tid by Molmil
Combined linker domain of N-DRC and associated proteins Tetrahymena
Descriptor: AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ...
Authors:Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H.
Deposit date:2023-07-19
Release date:2023-09-27
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8PVP
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BU of 8pvp by Molmil
Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FGJG18
Descriptor: Casein kinase II subunit alpha, SULFATE ION, ~{N}-[5-[(3-chloranyl-4-phenyl-phenyl)methylamino]pentyl]isoquinoline-5-sulfonamide
Authors:Kraemer, A, Greco, F, Gerninghaus, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-07-18
Release date:2023-09-20
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting.
Eur.J.Med.Chem., 276, 2024
8PVO
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BU of 8pvo by Molmil
Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FG5
Descriptor: 1,2-ETHANEDIOL, 2-[1-(1,3-benzothiazol-6-ylsulfonyl)piperidin-4-yl]-~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]ethanamine, Casein kinase II subunit alpha, ...
Authors:Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-07-18
Release date:2023-09-20
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting.
Eur.J.Med.Chem., 276, 2024
8TI1
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BU of 8ti1 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TI2
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BU of 8ti2 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TI0
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BU of 8ti0 by Molmil
ATP-1 state of Bcs1 (unsymmetrized)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-07-18
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8PVX
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BU of 8pvx by Molmil
Structure of the Lifeact13-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Belyy, A, Raunser, S.
Deposit date:2023-07-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:To be published
To Be Published
8THY
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BU of 8thy by Molmil
Yeast actin A167E mutant rabbit-like
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION
Authors:Volkmann, N, Hanein, D.
Deposit date:2023-07-18
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:yeast actin A167E mutant rabbit-like
To Be Published
8THX
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BU of 8thx by Molmil
Yeast actin A167E mutant wt-like
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION
Authors:Volkmann, N, Hanein, D.
Deposit date:2023-07-18
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:yeast actin A167E mutant wt-like
To Be Published
8PUH
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BU of 8puh by Molmil
Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-CTD refinement
Descriptor: Gag polyprotein
Authors:Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M.
Deposit date:2023-07-17
Release date:2023-08-23
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice
Nat.Struct.Mol.Biol., 2024
8PUG
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BU of 8pug by Molmil
Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-NTD refinement
Descriptor: Gag polyprotein
Authors:Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M.
Deposit date:2023-07-17
Release date:2023-08-23
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice
Nat.Struct.Mol.Biol., 2024
8PUQ
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BU of 8puq by Molmil
MetHemoglobin structure from serial synchrotron crystallography with fixed target
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bjelcic, M, Sigfridsson Clauss, K, Aurelius, O, Milas, M, Nan, J, Ursby, T.
Deposit date:2023-07-17
Release date:2023-10-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Anaerobic fixed-target serial crystallography using sandwiched silicon nitride membranes.
Acta Crystallogr D Struct Biol, 79, 2023
8PVK
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BU of 8pvk by Molmil
Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite structure
Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
Deposit date:2023-07-17
Release date:2023-12-06
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
8PVL
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BU of 8pvl by Molmil
Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite structure
Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R.
Deposit date:2023-07-17
Release date:2023-12-06
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (2.19 Å)
Cite:Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023

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數據於2024-09-11公開中

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