2DE9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2de9 by Molmil](/molmil-images/mine/2de9) | |
1VLZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vlz by Molmil](/molmil-images/mine/1vlz) | |
1VMC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vmc by Molmil](/molmil-images/mine/1vmc) | STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA) | Descriptor: | Stromal cell-derived factor 1 | Authors: | Gozansky, E.K, Clore, G.M. | Deposit date: | 2004-09-20 | Release date: | 2005-03-01 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha. J.Mol.Biol., 345, 2005
|
|
1JTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jtp by Molmil](/molmil-images/mine/1jtp) | Degenerate interfaces in antigen-antibody complexes | Descriptor: | FORMIC ACID, LYSOZYME C, SODIUM ION, ... | Authors: | Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L. | Deposit date: | 2001-08-21 | Release date: | 2001-12-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Degenerate interfaces in antigen-antibody complexes. J.Mol.Biol., 313, 2001
|
|
1JV8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jv8 by Molmil](/molmil-images/mine/1jv8) | NMR Structure of BPTI Mutant G37A | Descriptor: | TRYPSIN INHIBITOR | Authors: | Battiste, J.L, Li, R, Woodward, C. | Deposit date: | 2001-08-28 | Release date: | 2001-09-12 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility Biochemistry, 41, 2002
|
|
2DH8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dh8 by Molmil](/molmil-images/mine/2dh8) | Solution structure of the N-terminal RNA binding domain in DAZ-associated protein 1 | Descriptor: | DAZ-associated protein 1 | Authors: | Arai, S, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-23 | Release date: | 2006-09-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal RNA binding domain in DAZ-associated protein 1 To be Published
|
|
2DI2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2di2 by Molmil](/molmil-images/mine/2di2) | NMR structure of the HIV-2 nucleocapsid protein | Descriptor: | Nucleocapsid protein p7, ZINC ION | Authors: | Matsui, T, Kodera, Y, Endoh, H, Miyauchi, E, Komatsu, H, Sato, K, Tanaka, T, Kohno, T, Maeda, T. | Deposit date: | 2006-03-27 | Release date: | 2007-03-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | RNA Recognition Mechanism of the Minimal Active Domain of the Human Immunodeficiency Virus Type-2 Nucleocapsid Protein J.Biochem.(Tokyo), 141, 2007
|
|
1VEB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1veb by Molmil](/molmil-images/mine/1veb) | Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 5 | Descriptor: | (3R,4R)-N-{4-[4-(2-FLUORO-6-HYDROXY-3-METHOXY-BENZOYL)-BENZYLOXY]-AZEPAN-3-YL}-ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | Authors: | Breitenlechner, C.B, Wegge, T, Berillon, L, Graul, K, Marzenell, K, Friebe, W.-G, Thomas, U, Schumacher, R, Huber, R, Engh, R.A, Masjost, B. | Deposit date: | 2004-03-29 | Release date: | 2005-03-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structure-based optimization of novel azepane derivatives as PKB inhibitors J.Med.Chem., 47, 2004
|
|
1JWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jwn by Molmil](/molmil-images/mine/1jwn) | Crystal Structure of Scapharca inaequivalvis HbI, I114F Mutant Ligated to Carbon Monoxide. | Descriptor: | CARBON MONOXIDE, Globin I - Ark Shell, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Knapp, J.E, Gibson, Q.H, Cushing, L, Royer Jr, W.E. | Deposit date: | 2001-09-04 | Release date: | 2001-12-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Restricting the ligand-linked heme movement in Scapharca dimeric hemoglobin reveals tight coupling between distal and proximal contributions to cooperativity. Biochemistry, 40, 2001
|
|
2DIV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2div by Molmil](/molmil-images/mine/2div) | Solution structure of the RRM domain of TRNA selenocysteine associated protein | Descriptor: | TRNA selenocysteine associated protein | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-30 | Release date: | 2006-09-30 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RRM domain of TRNA selenocysteine associated protein To be Published
|
|
1JDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jdo by Molmil](/molmil-images/mine/1jdo) | |
2XCK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xck by Molmil](/molmil-images/mine/2xck) | Crystal structure of PDK1 in complex with a pyrazoloquinazoline inhibitor | Descriptor: | 1-METHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, GLYCEROL, ... | Authors: | Angiolini, M, Banfi, P, Casale, E, Casuscelli, F, Fiorelli, C, Saccardo, M.B, Silvagni, M, Zuccotto, F. | Deposit date: | 2010-04-23 | Release date: | 2010-07-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Optimization of Potent Pdk1 Inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
|
|
1K1A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k1a by Molmil](/molmil-images/mine/1k1a) | Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family | Descriptor: | B-cell lymphoma 3-encoded protein | Authors: | Michel, F, Soler-Lopez, M, Petosa, C, Cramer, P, Siebenlist, U, Mueller, C.W. | Deposit date: | 2001-09-24 | Release date: | 2001-11-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family. EMBO J., 20, 2001
|
|
1JAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jah by Molmil](/molmil-images/mine/1jah) | H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MAGNESIUM | Descriptor: | C-HA-RAS, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Schweins, T, Scheffzek, K, Assheuer, R, Wittinghofer, A. | Deposit date: | 1996-12-15 | Release date: | 1997-07-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+. J.Mol.Biol., 266, 1997
|
|
2V7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v7o by Molmil](/molmil-images/mine/2v7o) | Crystal structure of human calcium-calmodulin-dependent protein kinase II gamma | Descriptor: | 1,2-ETHANEDIOL, BISINDOLYLMALEIMIDE IX, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II GAMMA CHAIN | Authors: | Pike, A.C.W, Rellos, P, Fedorov, O, Burgess-Brown, N, Shrestha, L, Ugochukwu, E, Pilka, E.S, von Delft, F, Edwards, A, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Knapp, S. | Deposit date: | 2007-07-31 | Release date: | 2007-09-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation. Plos Biol., 8, 2010
|
|
2DMO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dmo by Molmil](/molmil-images/mine/2dmo) | Refined solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2) | Descriptor: | Neutrophil cytosol factor 2 | Authors: | Tochio, N, Chikayama, E, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-22 | Release date: | 2006-05-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2) To be Published
|
|
2DMU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dmu by Molmil](/molmil-images/mine/2dmu) | Solution structure of the homeobox domain of Homeobox protein goosecoid | Descriptor: | Homeobox protein goosecoid | Authors: | Ohnishi, S, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-24 | Release date: | 2006-10-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the homeobox domain of Homeobox protein goosecoid To be Published
|
|
1JAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jai by Molmil](/molmil-images/mine/1jai) | H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MANGANESE | Descriptor: | C-HA-RAS, MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Schweins, T, Scheffzek, K, Assheuer, R, Wittinghofer, A. | Deposit date: | 1996-12-15 | Release date: | 1997-07-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+. J.Mol.Biol., 266, 1997
|
|
2DNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dnu by Molmil](/molmil-images/mine/2dnu) | Solution structure of RSGI RUH-061, a SH3 domain from human | Descriptor: | SH3 multiple domains 1 | Authors: | Ohashi, W, Hirota, H, Nagashima, T, Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-26 | Release date: | 2006-10-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of RSGI RUH-061, a SH3 domain from human to be published
|
|
1VG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vg8 by Molmil](/molmil-images/mine/1vg8) | GPPNHP-Bound Rab7 | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-7 | Authors: | Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K. | Deposit date: | 2004-04-23 | Release date: | 2004-07-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease Cell(Cambridge,Mass.), 117, 2004
|
|
8K5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k5c by Molmil](/molmil-images/mine/8k5c) | |
8K5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k5d by Molmil](/molmil-images/mine/8k5d) | |
1JSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jsa by Molmil](/molmil-images/mine/1jsa) | MYRISTOYLATED RECOVERIN WITH TWO CALCIUMS BOUND, NMR, 24 STRUCTURES | Descriptor: | CALCIUM ION, MYRISTIC ACID, RECOVERIN | Authors: | Ames, J.B, Ishima, R, Tanaka, T, Gordon, J.I, Stryer, L, Ikura, M. | Deposit date: | 1997-06-04 | Release date: | 1997-10-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Molecular mechanics of calcium-myristoyl switches. Nature, 389, 1997
|
|
8K5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k5b by Molmil](/molmil-images/mine/8k5b) | |
2XBJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xbj by Molmil](/molmil-images/mine/2xbj) | Crystal Structure of Chk2 in complex with an inhibitor | Descriptor: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, NITRATE ION, ... | Authors: | Anderson, V.E, Walton, M.I, Eve, P.D, Caldwell, J.J, Pearl, L.H, Oliver, A.W, Collins, I, Garrett, M.D. | Deposit date: | 2010-04-12 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. J.Med.Chem., 54, 2011
|
|