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2IUW
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BU of 2iuw by Molmil
Crystal structure of human ABH3 in complex with iron ion and 2- oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, ALKYLATED REPAIR PROTEIN ALKB HOMOLOG 3, BETA-MERCAPTOETHANOL, ...
Authors:Sundheim, O, Vagbo, C.B, Bjoras, M, deSousa, M.M.L, Talstad, V, Aas, P.A, Drablos, F, Krokan, H.E, Tainer, J.A, Slupphaug, G.
Deposit date:2006-06-07
Release date:2006-07-26
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Human Abh3 Structure and Key Residues for Oxidative Demethylation to Reverse DNA/RNA Damage.
Embo J., 25, 2006
6SNA
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BU of 6sna by Molmil
Crystal structure of Antirestriction ArdC protein from R388 plasmid. Mn(II)-bound structure.
Descriptor: ArdC protein, MANGANESE (II) ION
Authors:Gonzalez-Montes, L, Moncalian, G.
Deposit date:2019-08-23
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:ArdC, a ssDNA-binding protein with a metalloprotease domain, overpasses the recipient hsdRMS restriction system broadening conjugation host range.
Plos Genet., 16, 2020
5CD4
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BU of 5cd4 by Molmil
The Type IE CRISPR Cascade complex from E. coli, with two assemblies in the asymmetric unit arranged back-to-back
Descriptor: CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ...
Authors:Jackson, R.N, Golden, S.M, Carter, J, Wiedenheft, B.
Deposit date:2015-07-03
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli.
Nucleic Acids Res., 43, 2015
8FYZ
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BU of 8fyz by Molmil
Crystal structure of human PARP1 ART domain bound to inhibitor UKTT10 (compound 13)
Descriptor: (2P)-2-{3-[(4R)-3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carbonyl]phenyl}-1H-benzimidazole-4-carboxamide, CITRIC ACID, DIMETHYL SULFOXIDE, ...
Authors:Rouleau-Turcotte, E, Pascal, J.M.
Deposit date:2023-01-27
Release date:2024-02-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.
Biochem.J., 481, 2024
8FYY
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BU of 8fyy by Molmil
Crystal structure of human PARP1 ART domain bound to inhibitor UKTT5 (compound 10)
Descriptor: 2-(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)-1H-benzimidazole-7-carboxamide, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Rouleau-Turcotte, E, Pascal, J.M.
Deposit date:2023-01-27
Release date:2024-02-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.
Biochem.J., 481, 2024
8FZ1
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BU of 8fz1 by Molmil
Crystal structure of human PARP1 ART domain bound to inhibitor UKTT22 (compound 14)
Descriptor: (2P)-2-{3-[(2-amino-4,5-dimethylphenyl)carbamoyl]phenyl}-1H-benzimidazole-4-carboxamide, 1,2-ETHANEDIOL, CITRIC ACID, ...
Authors:Rouleau-Turcotte, E, Pascal, J.M.
Deposit date:2023-01-27
Release date:2024-02-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.
Biochem.J., 481, 2024
2GCL
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BU of 2gcl by Molmil
Structure of the Pob3 Middle domain
Descriptor: CHLORIDE ION, Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region
Authors:VanDemark, A.P.
Deposit date:2006-03-14
Release date:2006-05-23
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition.
Mol.Cell, 22, 2006
2O4G
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BU of 2o4g by Molmil
Structure of TREX1 in complex with a nucleotide
Descriptor: MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, Three prime repair exonuclease 1
Authors:Brucet, M, Macias, M.J, Fita, I, Celada, A.
Deposit date:2006-12-04
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains.
J.Biol.Chem., 282, 2007
3I1D
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BU of 3i1d by Molmil
Distinct recognition of three-way DNA junctions by the two enantiomers of a metallo-supramolecular cylinder ('helicate')
Descriptor: 5'-D(*CP*GP*TP*AP*CP*G)-3', FE (II) ION, N-[(1E)-PYRIDIN-2-YLMETHYLENE]-N-[4-(4-{[(1E)-PYRIDIN-2-YLMETHYLENE]AMINO}BENZYL)PHENYL]AMINE
Authors:Boer, D.R, Uson, I, Hannon, M.J, Coll, M.
Deposit date:2009-06-26
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Self-Assembly of Functionalizable Two-Component 3D DNA Arrays through the Induced Formation of DNA Three-Way-Junction Branch Points by Supramolecular Cylinders.
Angew.Chem.Int.Ed.Engl., 49, 2010
8ASO
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BU of 8aso by Molmil
Nickel(II) bound to a non-canonical quadruplex
Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3'), NICKEL (II) ION
Authors:Lambert, M.C, Hall, J.P.
Deposit date:2022-08-19
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Identifying metal-DNA binding sites, what is the best method to get transition metals into a crystal system?
To Be Published
8ASM
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BU of 8asm by Molmil
Cobalt(II) bound to a non-canonical quadruplex
Descriptor: COBALT (II) ION, COBALT HEXAMMINE(III), DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3')
Authors:Lambert, M.C, Hall, J.P.
Deposit date:2022-08-19
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identifying metal-DNA binding sites, what is the best method to get transition metals into a crystal system?
To Be Published
2WIZ
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BU of 2wiz by Molmil
Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate
Descriptor: ARCHAEAL HJC, HALF-JUNCTION
Authors:Carolis, C, Koehler, C, Sauter, C, Basquin, J, Suck, D, Toeroe, I.
Deposit date:2009-05-18
Release date:2009-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structures of Holliday Junction Resolvases from Archaeoglobus Fulgidus Bound to DNA Substrate
To be Published
2WJ0
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BU of 2wj0 by Molmil
Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate
Descriptor: ARCHAEAL HJC, COBALT HEXAMMINE(III), HALF-JUNCTION
Authors:Carolis, C, Koehler, C, Sauter, C, Basquin, J, Suck, D, Toeroe, I.
Deposit date:2009-05-18
Release date:2009-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structures of Holliday Junction Resolvases from Archaeoglobus Fulgidus Bound to DNA Substrate
To be Published
8BAO
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BU of 8bao by Molmil
Dysgonamonadaceae bacterium CRISPR ancillary nuclease 2
Descriptor: BROMIDE ION, Cyclic tetra-adenylate (cA4), DUF1887 family protein, ...
Authors:Li, A.W.H, Doherty, A.J.
Deposit date:2022-10-11
Release date:2022-11-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
3GJJ
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BU of 3gjj by Molmil
crystal structure of a DNA duplex containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one
Descriptor: 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*(B7C)P*CP*GP*CP*G)-3'
Authors:Takenaka, A, Juan, E.C.M, Shimizu, S, Haraguchi, T, Xiao, M, Kurose, T, Ohkubo, A, Sekine, M, Shibata, T, Millington, C.L, Williams, D.M.
Deposit date:2009-03-09
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into the stabilizing contributions of bicyclic cytosine analogues: crystal structures of DNA duplexes containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one
To be Published
2QIC
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BU of 2qic by Molmil
Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide
Descriptor: H3K4ME3 PEPTIDE, Inhibitor of growth protein 1, ZINC ION
Authors:Pena, P.V, Champagne, K, Zhao, R, Kutateladze, T.G.
Deposit date:2007-07-03
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
J.Mol.Biol., 380, 2008
8BAG
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BU of 8bag by Molmil
Copper(II) bound to a non-canonical quadruplex containing the damaged base 8-oxoguanine
Descriptor: COBALT HEXAMMINE(III), COPPER (II) ION, DNA (5'-D(*(8OG)P*CP*AP*TP*GP*CP*T)-3')
Authors:Lambert, M.C, Hall, J.P.
Deposit date:2022-10-11
Release date:2023-10-25
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Oxidative damage induce copper(II)-DNA binding
To Be Published
8BAE
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BU of 8bae by Molmil
Copper(II) bound to a non-canonical quadruplex
Descriptor: COBALT HEXAMMINE(III), COPPER (II) ION, DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3')
Authors:Lambert, M.C, Hall, J.P.
Deposit date:2022-10-11
Release date:2023-10-25
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Oxidative damage induce copper(II)-DNA binding
To Be Published
8BAF
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BU of 8baf by Molmil
Non-canonical quadruplex containing the oxidation product 8-oxoguanine
Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*(8OG)P*CP*AP*TP*GP*CP*T)-3')
Authors:Lambert, M.C, Hall, J.P.
Deposit date:2022-10-11
Release date:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Oxidative damage induce copper(II)-DNA binding
To Be Published
8CLJ
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BU of 8clj by Molmil
TFIIIC TauB-DNA dimer
Descriptor: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ...
Authors:Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W.
Deposit date:2023-02-16
Release date:2023-06-21
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
1PGZ
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BU of 1pgz by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Moore, S.A, Shamoo, Y.
Deposit date:2003-05-28
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.Biol.Chem., 278, 2003
1JMS
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BU of 1jms by Molmil
Crystal Structure of the Catalytic Core of Murine Terminal Deoxynucleotidyl Transferase
Descriptor: MAGNESIUM ION, SODIUM ION, TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE
Authors:Delarue, M, Boule, J.B, Lescar, J, Expert-Bezancon, N, Sukumar, N, Jourdan, N, Rougeon, F, Papanicolaou, C.
Deposit date:2001-07-19
Release date:2002-01-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase.
Embo J., 21, 2002
5C12
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BU of 5c12 by Molmil
Nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6
Descriptor: Gene 2 protein, MAGNESIUM ION
Authors:Zhao, H, Tang, L.
Deposit date:2015-06-12
Release date:2015-10-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
4Y18
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BU of 4y18 by Molmil
Structure of BRCA1 BRCT domains in complex with Abraxas double phosphorylated peptide
Descriptor: BRCA1-A complex subunit Abraxas, Breast cancer type 1 susceptibility protein
Authors:Wu, Q, Blundell, T.L.
Deposit date:2015-02-06
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.
Mol.Cell, 61, 2016
4Y2G
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BU of 4y2g by Molmil
Structure of BRCA1 BRCT domains in complex with Abraxas single phosphorylated peptide
Descriptor: BRCA1-A complex subunit Abraxas, Breast cancer type 1 susceptibility protein
Authors:Wu, Q, Blundell, T.L.
Deposit date:2015-02-09
Release date:2016-01-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.
Mol.Cell, 61, 2016

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數據於2024-09-04公開中

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