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8XGA
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Crystal structure of human Golgi resident glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-((tetrahydro-2H-pyran-4-yl)oxy)indolin-2-one
Descriptor: (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-(oxan-4-yloxy)-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-15
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (3.537 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
8XG2
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BU of 8xg2 by Molmil
The structure of HLA-A/Pep14
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-14
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
8XFZ
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BU of 8xfz by Molmil
The structure of HLA-A/L1-2
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-14
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
8XFY
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BU of 8xfy by Molmil
The Crystal Structure of RSK2 from Biortus.
Descriptor: 2,6-bis(fluoranyl)-4-[4-(4-morpholin-4-ylphenyl)pyridin-3-yl]phenol, Ribosomal protein S6 kinase alpha-3
Authors:Wang, F, Cheng, W, Lv, Z, Lin, D, Pan, W.
Deposit date:2023-12-14
Release date:2024-03-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Crystal Structure of RSK2 from Biortus.
To Be Published
8XFV
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BU of 8xfv by Molmil
Crystal structure of human Golgi resident glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-(piperidin-4-yloxy)indolin-2-one
Descriptor: 3-(1~{H}-benzimidazol-5-ylmethylidene)-4-piperidin-4-yloxy-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-14
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
8XFR
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Structure of the alginate epimerase/lyase complexed with tetra-mannuronic acid
Descriptor: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Fujiwara, T.
Deposit date:2023-12-14
Release date:2024-05-15
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum.
Febs Lett., 598, 2024
8XFQ
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Structure of the alginate epimerase/lyase complexed with penta-mannuronic acid
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ...
Authors:Fujiwara, T.
Deposit date:2023-12-14
Release date:2024-05-15
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum.
Febs Lett., 598, 2024
8XFM
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BU of 8xfm by Molmil
The Crystal Structure of MNK2 from Biortus.
Descriptor: 1,2-ETHANEDIOL, 5-(3-azanyl-1~{H}-indazol-6-yl)-1-[(3-chlorophenyl)methyl]pyridin-2-one, MAP kinase-interacting serine/threonine-protein kinase 2, ...
Authors:Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J.
Deposit date:2023-12-14
Release date:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of MNK2 from Biortus.
To Be Published
8XFL
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The Crystal Structure of MARK4 from Biortus.
Descriptor: MAP/microtubule affinity-regulating kinase 4
Authors:Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J.
Deposit date:2023-12-14
Release date:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of MARK4 from Biortus.
To Be Published
8XFD
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BU of 8xfd by Molmil
Crystal structure of pyruvate kinase tetramer in complex with allosteric activator, Mitapivat (MTPV, AG-348)
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, Isoform L-type of Pyruvate kinase PKLR, MAGNESIUM ION, ...
Authors:Sun, R, Achour, A.
Deposit date:2023-12-13
Release date:2024-05-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348
Crystals, 2024
8XF3
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BU of 8xf3 by Molmil
Crystal structure of the reassembled C-phycocyanin octamer from Thermoleptolyngbya sp. O-77
Descriptor: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHOSPHATE ION, ...
Authors:Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S.
Deposit date:2023-12-13
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
8XF2
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BU of 8xf2 by Molmil
Crystal structure of the reassembled C-phycocyanin hexamer from Thermoleptolyngbya sp. O-77
Descriptor: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHOSPHATE ION, ...
Authors:Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S.
Deposit date:2023-12-13
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
8XF1
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BU of 8xf1 by Molmil
Crystal structure of the dissociated C-phycocyanin beta-chain from Thermoleptolyngbya sp. O-77
Descriptor: C-phycocyanin beta chain, PHYCOCYANOBILIN
Authors:Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S.
Deposit date:2023-12-13
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
8XF0
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BU of 8xf0 by Molmil
Crystal structure of the dissociated C-phycocyanin alpha-chain from Thermoleptolyngbya sp. O-77
Descriptor: C-phycocyanin alpha chain, MAGNESIUM ION, PHYCOCYANOBILIN
Authors:Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S.
Deposit date:2023-12-13
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
8XEY
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BU of 8xey by Molmil
The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ribosomal protein S6 kinase alpha-3
Authors:Wang, F, Cheng, W, Lv, Z, Meng, Q, Zhang, B.
Deposit date:2023-12-13
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus
To Be Published
8XES
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BU of 8xes by Molmil
The structure of HLA-A/L1-1
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-12
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
8XEQ
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BU of 8xeq by Molmil
Solution NMR structure of DNA sequence d(CGATCG)2
Descriptor: DNA (5'-D(*CP*AP*CP*GP*TP*GP*)-3')
Authors:Nair, M.S, Kumar, S.
Deposit date:2023-12-12
Release date:2024-01-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR structure of DNA sequence d(CGATCG)2
To Be Published
8XEP
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BU of 8xep by Molmil
Crystal structure of a Legionella pneumophila type IV effector in complex with ubiquitin
Descriptor: SULFATE ION, Type IV effector MavL, Ubiquitin
Authors:Tan, J.X, Wang, X.F, Zhou, Y, Zhu, Y.Q.
Deposit date:2023-12-12
Release date:2024-05-01
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling.
Nature, 2024
8XEJ
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BU of 8xej by Molmil
Cryo-EM structure of human XKR8-basigin complex in lipid nanodisc
Descriptor: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab heavy chain, Fab light chain, ...
Authors:Sakuragi, T.S, Kanai, R.K, Kikkawa, M.K, Toyoshima, C.T, Nagata, S.N.
Deposit date:2023-12-12
Release date:2024-02-28
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase.
J.Biol.Chem., 300, 2024
8XEG
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BU of 8xeg by Molmil
Cryo-EM structure of Adeno-associated Virus 9P31 in 1.76 angstrom.
Descriptor: Capsid protein VP1
Authors:Zhang, R, Liu, Y, Lou, Z.
Deposit date:2023-12-12
Release date:2024-01-24
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (1.76 Å)
Cite:Structural basis of the recognition of adeno-associated virus by the neurological system-related receptor carbonic anhydrase IV.
Plos Pathog., 20, 2024
8XEA
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BU of 8xea by Molmil
XBB.1.5 spike protein in complex with BD55-1205
Descriptor: BD55-1205 heavy chain, BD55-1205 light chain, Spike glycoprotein
Authors:Feng, L.L.
Deposit date:2023-12-11
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:XBB.1.5 spike protein in complex with BD55-1205
To Be Published
8XE9
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BU of 8xe9 by Molmil
XBB.1.5 RBD in complex with BD55-1205
Descriptor: BD55-1205 heavy chain, BD55-1205 light chain, Spike protein S2'
Authors:Feng, L.L.
Deposit date:2023-12-11
Release date:2024-03-06
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:XBB.1.5 RBD in complex with BD55-1205
To Be Published
8XE7
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BU of 8xe7 by Molmil
Crystal structure of human Sirt2 without Sirt2-specific insertion
Descriptor: NAD-dependent protein deacetylase sirtuin-2, ZINC ION
Authors:Konuma, T, Akashi, S.
Deposit date:2023-12-11
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Biophysical insights into the dimer formation of human Sirtuin 2.
Protein Sci., 33, 2024
8XD6
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BU of 8xd6 by Molmil
Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus in complex with NADPH, AKG and NH4 in the steady stage of reaction
Descriptor: 2-OXOGLUTARIC ACID, AMMONIUM ION, Glutamate dehydrogenase, ...
Authors:Wakabayashi, T, Oide, M, Nakasako, M.
Deposit date:2023-12-10
Release date:2023-12-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024
8XD5
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BU of 8xd5 by Molmil
Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus in complex with NADP and GLU in the steady stage of reaction
Descriptor: GAMMA-L-GLUTAMIC ACID, Glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wakabayashi, T, Oide, M, Nakasako, M.
Deposit date:2023-12-10
Release date:2023-12-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024

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數據於2024-07-17公開中

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