6WAE
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![BU of 6wae by Molmil](/molmil-images/mine/6wae) | Crystal Structure of 6X-His tagged SmcR | Descriptor: | 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION | Authors: | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | Deposit date: | 2020-03-25 | Release date: | 2020-06-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences. Nucleic Acids Res., 49, 2021
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6WAG
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![BU of 6wag by Molmil](/molmil-images/mine/6wag) | Crystal Structure of SmcR S76A from Vibrio Vulnificus | Descriptor: | 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION | Authors: | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | Deposit date: | 2020-03-25 | Release date: | 2020-06-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.575 Å) | Cite: | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences. Nucleic Acids Res., 49, 2021
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6WAI
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![BU of 6wai by Molmil](/molmil-images/mine/6wai) | Crystal Structure of SmcR N142D from Vibrio vulnificus | Descriptor: | 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION | Authors: | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | Deposit date: | 2020-03-25 | Release date: | 2020-06-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.583 Å) | Cite: | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences. Nucleic Acids Res., 49, 2021
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7UBO
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![BU of 7ubo by Molmil](/molmil-images/mine/7ubo) | Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor CCD-956 | Descriptor: | Bromodomain testis-specific protein, DIMETHYL SULFOXIDE, N-[(2R)-1-(methylamino)-3-{1-[(4-methyl-2-oxo-1,2-dihydroquinolin-6-yl)acetyl]piperidin-4-yl}-1-oxopropan-2-yl]-5-phenylpyridine-2-carboxamide | Authors: | Ta, H.M, Modukuri, R.K, Yu, Z, Tan, Z, Matzuk, M.M, Kim, C. | Deposit date: | 2022-03-15 | Release date: | 2022-06-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections. Proc.Natl.Acad.Sci.USA, 119, 2022
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6HPB
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![BU of 6hpb by Molmil](/molmil-images/mine/6hpb) | |
6OJ0
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![BU of 6oj0 by Molmil](/molmil-images/mine/6oj0) | Cryo-EM reconstruction of Sulfolobus polyhedral virus 1 (SPV1) | Descriptor: | Structural protein VP4, Uncharacterized protein | Authors: | Wang, F, Liu, Y, Conway, J.F, Krupovic, M, Prangishvili, D, Egelman, E.H. | Deposit date: | 2019-04-10 | Release date: | 2019-10-02 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | A packing for A-form DNA in an icosahedral virus. Proc.Natl.Acad.Sci.USA, 116, 2019
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1D8J
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![BU of 1d8j by Molmil](/molmil-images/mine/1d8j) | SOLUTION STRUCTURE OF THE CENTRAL CORE DOMAIN OF TFIIE BETA | Descriptor: | GENERAL TRANSCRIPTION FACTOR TFIIE-BETA | Authors: | Okuda, M, Watanabe, Y, Okamura, H, Hanaoka, F, Ohkuma, Y, Nishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1999-10-25 | Release date: | 2000-04-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the central core domain of TFIIEbeta with a novel double-stranded DNA-binding surface. EMBO J., 19, 2000
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1D8K
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![BU of 1d8k by Molmil](/molmil-images/mine/1d8k) | SOLUTION STRUCTURE OF THE CENTRAL CORE DOMAIN OF TFIIE BETA | Descriptor: | GENERAL TRANSCRIPTION FACTOR TFIIE-BETA | Authors: | Okuda, M, Watanabe, Y, Okamura, H, Hanaoka, F, Ohkuma, Y, Nishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1999-10-25 | Release date: | 2000-04-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the central core domain of TFIIEbeta with a novel double-stranded DNA-binding surface. EMBO J., 19, 2000
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2XRN
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![BU of 2xrn by Molmil](/molmil-images/mine/2xrn) | Crystal structure of TtgV | Descriptor: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV | Authors: | Lu, D, Fillet, S, Meng, C, Alguel, Y, Kloppsteck, P, Bergeron, J, Krell, T, Gallegos, M.-T, Ramos, J, Zhang, X. | Deposit date: | 2010-09-17 | Release date: | 2010-12-01 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators. Genes Dev., 24, 2010
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6IUB
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![BU of 6iub by Molmil](/molmil-images/mine/6iub) | Structure of Helicobacter pylori Soj protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SpoOJ regulator (Soj) | Authors: | Chu, C.H, Yen, C.Y, Sun, Y.J. | Deposit date: | 2018-11-28 | Release date: | 2019-02-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Crystal structures of HpSoj-DNA complexes and the nucleoid-adaptor complex formation in chromosome segregation. Nucleic Acids Res., 47, 2019
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5LW6
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![BU of 5lw6 by Molmil](/molmil-images/mine/5lw6) | |
3VEB
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![BU of 3veb by Molmil](/molmil-images/mine/3veb) | Crystal Structure of Matp-matS | Descriptor: | 5'-D(*AP*CP*GP*TP*GP*AP*CP*AP*AP*TP*GP*TP*CP*AP*CP*G)-3', 5'-D(*TP*CP*GP*TP*GP*AP*CP*AP*TP*TP*GP*TP*CP*AP*CP*G)-3', CALCIUM ION, ... | Authors: | Schumacher, M.A. | Deposit date: | 2012-01-07 | Release date: | 2012-11-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis for a protein-mediated DNA-bridging mechanism that functions in condensation of the E. coli chromosome. Mol.Cell, 48, 2012
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3VEA
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![BU of 3vea by Molmil](/molmil-images/mine/3vea) | Crystal Structure of matP-matS23mer | Descriptor: | 5'-D(*AP*GP*TP*TP*CP*GP*TP*GP*AP*CP*AP*AP*TP*GP*TP*CP*AP*CP*GP*AP*AP*CP*T)-3', 5'-D(*AP*GP*TP*TP*CP*GP*TP*GP*AP*CP*AP*TP*TP*GP*TP*CP*AP*CP*GP*AP*AP*CP*T)-3', Macrodomain Ter protein | Authors: | Schumacher, M.A. | Deposit date: | 2012-01-07 | Release date: | 2012-11-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular basis for a protein-mediated DNA-bridging mechanism that functions in condensation of the E. coli chromosome. Mol.Cell, 48, 2012
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3QU3
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![BU of 3qu3 by Molmil](/molmil-images/mine/3qu3) | Crystal structure of IRF-7 DBD apo form | Descriptor: | 1,2-ETHANEDIOL, Interferon regulatory factor 7, SODIUM ION | Authors: | De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K. | Deposit date: | 2011-02-23 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding. Nucleic Acids Res., 39, 2011
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2JUL
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![BU of 2jul by Molmil](/molmil-images/mine/2jul) | NMR Structure of DREAM | Descriptor: | CALCIUM ION, Calsenilin | Authors: | Ames, J. | Deposit date: | 2007-08-30 | Release date: | 2008-04-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization. Biochemistry, 47, 2008
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3QU6
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![BU of 3qu6 by Molmil](/molmil-images/mine/3qu6) | Crystal structure of IRF-3 DBD free form | Descriptor: | CHLORIDE ION, IRF3 protein, SODIUM ION, ... | Authors: | De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K. | Deposit date: | 2011-02-23 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding. Nucleic Acids Res., 39, 2011
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1BGW
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![BU of 1bgw by Molmil](/molmil-images/mine/1bgw) | TOPOISOMERASE RESIDUES 410-1202, | Descriptor: | TOPOISOMERASE | Authors: | Berger, J.M, Gamblin, S.J, Harrison, S.C, Wang, J.C. | Deposit date: | 1996-02-20 | Release date: | 1996-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and mechanism of DNA topoisomerase II. Nature, 379, 1996
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2LZ1
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![BU of 2lz1 by Molmil](/molmil-images/mine/2lz1) | Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O | Descriptor: | Nuclear factor erythroid 2-related factor 2 | Authors: | Eletsky, A, Pulavarti, S.V.S.R.K, Lee, D, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-09-22 | Release date: | 2012-11-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O To be Published
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3MQI
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![BU of 3mqi by Molmil](/molmil-images/mine/3mqi) | Human early B-cell factor 1 (EBF1) IPT/TIG domain | Descriptor: | ETHYL MERCURY ION, Transcription factor COE1, trimethylamine oxide | Authors: | Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schueler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-04-28 | Release date: | 2010-05-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
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2O8K
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![BU of 2o8k by Molmil](/molmil-images/mine/2o8k) | NMR Structure of the Sigma-54 RpoN Domain Bound to the-24 Promoter Element | Descriptor: | 5'-D(*GP*AP*AP*AP*CP*GP*TP*GP*CP*CP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*GP*CP*AP*CP*GP*TP*TP*TP*C)-3', RNA polymerase sigma factor RpoN | Authors: | Doucleff, M, Pelton, J.G, Lee, P.S, Wemmer, D.E. | Deposit date: | 2006-12-12 | Release date: | 2007-07-17 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structural basis of DNA recognition by the alternative sigma-factor, sigma54. J.Mol.Biol., 369, 2007
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4MUO
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![BU of 4muo by Molmil](/molmil-images/mine/4muo) | The TrpD2 enzyme from E.coli: YbiB | Descriptor: | Uncharacterized protein YbiB | Authors: | Stutz, C, Mayans, O. | Deposit date: | 2013-09-23 | Release date: | 2015-03-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | YbiB from Escherichia coli, the Defining Member of the Novel TrpD2 Family of Prokaryotic DNA-binding Proteins. J.Biol.Chem., 290, 2015
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3N50
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![BU of 3n50 by Molmil](/molmil-images/mine/3n50) | Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains | Descriptor: | Transcription factor COE3 | Authors: | Lehtio, L, Siponen, M.I, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schuler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-05-24 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
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1QRY
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![BU of 1qry by Molmil](/molmil-images/mine/1qry) | Homeobox protein VND (ventral nervous system defective protein) | Descriptor: | PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN) | Authors: | Xiang, B. | Deposit date: | 1999-06-16 | Release date: | 1999-07-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Distortion of the three-dimensional structure of the vnd/NK-2 homeodomain bound to DNA induced by an embryonically lethal A35T point mutation. Biochemistry, 42, 2003
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2OVG
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![BU of 2ovg by Molmil](/molmil-images/mine/2ovg) | Lambda Cro Q27P/A29S/K32Q triple mutant at 1.35 A in space group P3221 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Phage lambda Cro, SULFATE ION | Authors: | Hall, B.M, Heroux, A, Roberts, S.A, Cordes, M.H. | Deposit date: | 2007-02-13 | Release date: | 2008-01-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Two structures of a lambda Cro variant highlight dimer flexibility but disfavor major dimer distortions upon specific binding of cognate DNA. J.Mol.Biol., 375, 2008
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7RX0
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![BU of 7rx0 by Molmil](/molmil-images/mine/7rx0) | Complex of AMPPNP-Kif7 and Gli2 Zinc-Finger domain bound to microtubules | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF7, MAGNESIUM ION, ... | Authors: | Mani, N, Wilson-Kubalek, E.M, Haque, F, Freniere, C, Milligan, R.A, Subramanian, R. | Deposit date: | 2021-08-20 | Release date: | 2022-06-15 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Cytoskeletal regulation of a transcription factor by DNA mimicry via coiled-coil interactions. Nat.Cell Biol., 24, 2022
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