3MQI

Human early B-cell factor 1 (EBF1) IPT/TIG domain

Summary for 3MQI

Entry DOI	10.2210/pdb3mqi/pdb
Descriptor	Transcription factor COE1, ETHYL MERCURY ION, trimethylamine oxide, ... (4 entities in total)
Functional Keywords	immunoglobulin like fold, structural genomics, structural genomics consortium, sgc, transcription activator
Biological source	Homo sapiens (human)
Cellular location	Nucleus (Potential): Q9UH73
Total number of polymer chains	3
Total formula weight	32905.24
Authors	Siponen, M.I.,Lehtio, L.,Arrowsmith, C.H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Schueler, H.,Schutz, P.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Wisniewska, M.,Berglund, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-04-28, release date: 2010-05-26, Last modification date: 2024-02-21)
Primary citation	Siponen, M.I.,Wisniewska, M.,Lehtio, L.,Johansson, I.,Svensson, L.,Raszewski, G.,Nilsson, L.,Sigvardsson, M.,Berglund, H. Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285:25875-25879, 2010 Cited by PubMed: 20592035 DOI: 10.1074/jbc.C110.150482 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation