PDB: 215264 resultsInfo pagesStatus searchChemie searchBIRD

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3CJ0	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments Descriptor: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase Authors: Kissinger, c. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
2LNM	Solution structure of the C-terminal NP-repeat domain of Tic40, a co-chaperone during protein import into chloroplasts Descriptor: Protein TIC 40, chloroplastic Authors: Chen, C, Kao, Y. Deposit date: 2012-01-01 Release date: 2012-11-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure of the C-terminal NP-repeat domain of Tic40, a co-chaperone during protein import into chloroplasts. J.Biochem., 152, 2012
335D	THE CRYSTAL STRUCTURE OF THE DNA DECAMER D(GGCAATTGCG) CONTAINS BOTH MAJOR AND MINOR GROOVE BINDING G.(G.C) TRIPLETS Descriptor: DNA (5'-D(*GP*GP*CP*AP*AP*TP*TP*GP*CP*G)-3'), MAGNESIUM ION Authors: Nunn, C.M, Neidle, S. Deposit date: 1997-06-05 Release date: 1998-08-10 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of the DNA decamer d(GGCAATTGCG) contains both major- and minor-groove binding G.(G.C) base triplets. Acta Crystallogr.,Sect.D, 54, 1998
3CJ3	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments Descriptor: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase Authors: Kissinger, c. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3CJ2	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments Descriptor: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase Authors: Kissinger, c. Deposit date: 2008-03-12 Release date: 2008-04-15 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3V46	Crystal Structure of Yeast Cdc73 C-Terminal Domain Descriptor: Cell division control protein 73 Authors: Amrich, C.G, VanDemark, A.P. Deposit date: 2011-12-14 Release date: 2012-02-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.549 Å) Cite: Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. J.Biol.Chem., 287, 2012
2REU	Crystal Structure of the C-terminal of Sau3AI fragment Descriptor: MAGNESIUM ION, Type II restriction enzyme Sau3AI Authors: Hu, X, Yu, F, Xu, C, He, J. Deposit date: 2007-09-27 Release date: 2008-09-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure and function of C-terminal Sau3AI domain Biochim.Biophys.Acta, 1794, 2009
100D	CRYSTAL STRUCTURE OF THE HIGHLY DISTORTED CHIMERIC DECAMER R(C)D(CGGCGCCG)R(G)-SPERMINE COMPLEX-SPERMINE BINDING TO PHOSPHATE ONLY AND MINOR GROOVE TERTIARY BASE-PAIRING Descriptor: DNA/RNA (5'-R(*CP*)-D(*CP*GP*GP*CP*GP*CP*CP*GP*)-R(*G)-3'), SPERMINE Authors: Ban, C, Ramakrishnan, B, Sundaralingam, M. Deposit date: 1994-12-05 Release date: 1995-03-31 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the highly distorted chimeric decamer r(C)d(CGGCGCCG)r(G).spermine complex--spermine binding to phosphate only and minor groove tertiary base-pairing. Nucleic Acids Res., 22, 1994
2YLM	Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase. Descriptor: CHLORIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 Authors: Faesen, A.C, Perrakis, A, Sixma, T.K. Deposit date: 2011-06-03 Release date: 2011-10-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Mechanism of Usp7/Hausp Activation by its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation by Gmp-Synthetase Mol.Cell, 44, 2011
1I2T	X-RAY STRUCTURE OF THE HUMAN HYPERPLASTIC DISCS PROTEIN: AN ORTHOLOG OF THE C-TERMINAL DOMAIN OF POLY(A)-BINDING PROTEIN Descriptor: HYD PROTEIN Authors: Deo, R.C, Sonenberg, N, Burley, S.K. Deposit date: 2001-02-12 Release date: 2001-04-18 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.04 Å) Cite: X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein. Proc.Natl.Acad.Sci.USA, 98, 2001
2LWX	Solution structure of the C-terminal Pdr1-activating domain of the J-protein Zuo1 Descriptor: Zuotin Authors: Volkman, B.F, Ducett, J.K, Peterson, F.C, Craig, E.A. Deposit date: 2012-08-08 Release date: 2012-10-03 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Unfolding of the C-terminal domain of the j-protein zuo1 releases autoinhibition and activates pdr1-dependent transcription. J.Mol.Biol., 425, 2013
2J8P	NMR structure of C-terminal domain of human CstF-64 Descriptor: CLEAVAGE STIMULATION FACTOR 64 KDA SUBUNIT Authors: Qu, X, Perez-Canadillas, J.M, Agrawal, S, De Baecke, J, Cheng, H, Varani, G, Moore, C. Deposit date: 2006-10-27 Release date: 2006-11-06 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The C-Terminal Domains of Vertebrate Cstf-64 and its Yeast Orthologue RNA15 Form a New Structure Critical for Mrna 3'-End Processing. J.Biol.Chem., 282, 2007
2M45	NMR solution structure of the C-terminus of the minichromosome maintenance protein MCM from Sulfolobus solfataricus Descriptor: Minichromosome maintenance protein MCM Authors: Wiedemann, C, Ohlenschlager, O, Medagli, B, Onesti, S, Gorlach, M. Deposit date: 2013-01-29 Release date: 2014-01-29 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex Nucleic Acids Res., 43, 2015
161D	A SINGLE 2'-HYDROXYL GROUP CONVERTS B-DNA TO A-DNA: CRYSTAL STRUCTURE OF THE DNA-RNA CHIMERIC DECAMER DUPLEX D(CCGGC)R(G)D(CCGG) WITH A NOVEL INTERMOLECULAR G.C BASE-PAIRED QUADRUPLET Descriptor: DNA/RNA (5'-D(*CP*CP*GP*GP*CP*)-R(*GP*)-D(*CP*CP*GP*G)-3') Authors: Ban, C, Ramakrishnan, B, Sundaralingam, M. Deposit date: 1994-02-10 Release date: 1994-05-18 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A single 2'-hydroxyl group converts B-DNA to A-DNA. Crystal structure of the DNA-RNA chimeric decamer duplex d(CCGGC)r(G)d(CCGG) with a novel intermolecular G-C base-paired quadruplet. J.Mol.Biol., 236, 1994
1C7M	SOLUTION STRUCTURE OF THE FUNCTIONAL DOMAIN OF PARACOCCUS DENITRIFICANS CYTOCHROME C552 IN THE REDUCED STATE Descriptor: HEME C, PROTEIN (CYTOCHROME C552) Authors: Pristovsek, P, Luecke, C, Reincke, B, Ludwig, B, Rueterjans, H. Deposit date: 2000-03-03 Release date: 2000-07-19 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of the functional domain of Paracoccus denitrificans cytochrome c552 in the reduced state. Eur.J.Biochem., 267, 2000
1S62	Solution structure of the Escherichia coli TolA C-terminal domain Descriptor: TolA protein Authors: Deprez, C, Blanchard, L, Simorre, J.-P, Gavioli, M, Guerlesquin, F, Lazdunski, C, Lloubes, R, Marion, D. Deposit date: 2004-01-22 Release date: 2005-02-15 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Solution structure of the E.coli TolA C-terminal domain reveals conformational changes upon binding to the phage g3p N-terminal domain. J.Mol.Biol., 346, 2005
3R98	Joint Neutron and X-ray structure of Cytochrome c peroxidase Descriptor: Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE Authors: Blakeley, M.P, Fisher, S.J, Gumiero, A, Moody, P.C.E, Raven, E.L. Deposit date: 2011-03-25 Release date: 2012-04-04 Last modified: 2024-03-20 Method: NEUTRON DIFFRACTION (2.4 Å), X-RAY DIFFRACTION Cite: Hydrogen bonds in heme peroxidases: a combined X-ray and neutron study of cytochrome c peroxidase To be Published
1URF	HR1b domain from PRK1 Descriptor: PROTEIN KINASE C-LIKE 1 Authors: Owen, D, Lowe, P.N, Nietlispach, D, Brosnan, C.E, Chirgadze, D.Y, Parker, P.J, Blundell, T.L, Mott, H.R. Deposit date: 2003-10-29 Release date: 2003-11-06 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Molecular Dissection of the Interaction between the Small G Proteins Rac1 and Rhoa and Protein Kinase C-Related Kinase 1 (Prk1) J.Biol.Chem., 278, 2003
1CX1	SECOND N-TERMINAL CELLULOSE-BINDING DOMAIN FROM CELLULOMONAS FIMI BETA-1,4-GLUCANASE C, NMR, 22 STRUCTURES Descriptor: ENDOGLUCANASE C Authors: Brun, E, Johnson, P.E, Creagh, L.A, Haynes, C.A, Tomme, P, Webster, P, Kilburn, D.G, McIntosh, L.P. Deposit date: 1999-08-27 Release date: 2000-04-02 Last modified: 2017-02-01 Method: SOLUTION NMR Cite: Structure and binding specificity of the second N-terminal cellulose-binding domain from Cellulomonas fimi endoglucanase C. Biochemistry, 39, 2000
1COK	STRUCTURE OF THE C-TERMINAL DOMAIN OF P73 Descriptor: PROTEIN (SECOND SPLICE VARIANT P73) Authors: Chi, S.-W, Ayed, A, Arrowsmith, C.H. Deposit date: 1999-05-28 Release date: 1999-08-17 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain. EMBO J., 18, 1999
3QGE	Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-N-(4-methoxybenzyl)-1-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide Descriptor: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-N-(4-methoxybenzyl)-1-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide, RNA-directed RNA polymerase, ... Authors: Sheriff, S. Deposit date: 2011-01-24 Release date: 2011-04-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase. Bioorg.Med.Chem.Lett., 21, 2011
3QGD	Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide Descriptor: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide, RNA-directed RNA polymerase, ... Authors: Sheriff, S. Deposit date: 2011-01-24 Release date: 2011-04-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase. Bioorg.Med.Chem.Lett., 21, 2011
3R99	Joint Neutron and X-ray structure of Cytochrome c peroxidase Descriptor: Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE Authors: Blakeley, M.P, Fisher, S.J, Gumiero, A, Moody, P.C.E, Raven, E.L. Deposit date: 2011-03-25 Release date: 2012-04-04 Last modified: 2024-03-20 Method: NEUTRON DIFFRACTION (2.4 Å), X-RAY DIFFRACTION Cite: Hydrogen bonds in heme peroxidases: a combined X-ray and neutron study of cytochrome c peroxidase To be Published
1XZO	Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins Descriptor: CADMIUM ION, CALCIUM ION, Hypothetical protein ypmQ Authors: Ye, Q, Imriskova-Sosova, I, Hill, B.C, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2004-11-12 Release date: 2005-03-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.702 Å) Cite: Identification of a Disulfide Switch in BsSco, a Member of the Sco Family of Cytochrome c Oxidase Assembly Proteins Biochemistry, 44, 2005
2PX7	Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8 Descriptor: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Authors: Chen, L, Tsukuda, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Chen, L.-Q, Liu, Z.-J, Lee, D, Chang, S.-H, Nguyen, D, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-05-14 Release date: 2007-06-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8. To be Published

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