8TSH
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8TSL
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8TSR
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![BU of 8tsr by Molmil](/molmil-images/mine/8tsr) | Open, inward-facing MsbA structure (OIF4) | Descriptor: | ATP-binding transport protein MsbA | Authors: | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | Deposit date: | 2023-08-11 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8TSP
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![BU of 8tsp by Molmil](/molmil-images/mine/8tsp) | Open, inward-facing MsbA structure (OIF1) | Descriptor: | ATP-binding transport protein MsbA | Authors: | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | Deposit date: | 2023-08-11 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8TSO
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![BU of 8tso by Molmil](/molmil-images/mine/8tso) | KDL bound, nucleotide-free MsbA in open, outward-facing conformation | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-binding transport protein MsbA, PENTAETHYLENE GLYCOL MONODECYL ETHER | Authors: | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | Deposit date: | 2023-08-11 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8TSQ
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![BU of 8tsq by Molmil](/molmil-images/mine/8tsq) | Open, inward-facing MsbA structure (OIF2) | Descriptor: | ATP-binding transport protein MsbA | Authors: | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | Deposit date: | 2023-08-11 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8TSS
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![BU of 8tss by Molmil](/molmil-images/mine/8tss) | Open, inward-facing MsbA structure (OIF3) | Descriptor: | ATP-binding transport protein MsbA | Authors: | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | Deposit date: | 2023-08-11 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8Q61
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![BU of 8q61 by Molmil](/molmil-images/mine/8q61) | Co-crystal structure of human AKT2 with compound 3 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[4-(1-azanyl-3-methyl-3-oxidanyl-cyclobutyl)phenyl]-7-phenyl-1-propyl-pyrido[2,3-b][1,4]oxazin-2-one, GLYCEROL, ... | Authors: | Harrison, T, Barker, O. | Deposit date: | 2023-08-10 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development. Sci Rep, 12, 2022
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8Q62
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![BU of 8q62 by Molmil](/molmil-images/mine/8q62) | Early closed conformation of the g-tubulin ring complex | Descriptor: | Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... | Authors: | Llorca, O, Serna, M, Fernandez-Leiro, R. | Deposit date: | 2023-08-10 | Release date: | 2024-02-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Transition of human gamma-tubulin ring complex into a closed conformation during microtubule nucleation. Science, 383, 2024
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8TS0
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8KDX
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8TRN
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![BU of 8trn by Molmil](/molmil-images/mine/8trn) | Actin 1 from T. gondii in filaments bound to MgADP and jasplakinolide | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, Jasplakinolide, ... | Authors: | Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M. | Deposit date: | 2023-08-09 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover. Nat Commun, 15, 2024
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8TRM
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![BU of 8trm by Molmil](/molmil-images/mine/8trm) | Actin 1 from T. gondii in filaments bound to MgADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION | Authors: | Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M. | Deposit date: | 2023-08-09 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover. Nat Commun, 15, 2024
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8Q5J
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8Q52
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![BU of 8q52 by Molmil](/molmil-images/mine/8q52) | A PBP-like protein built from fragments of different folds | Descriptor: | Leucine-specific-binding protein,Chemotaxis protein CheY, SULFATE ION | Authors: | Shanmugaratnam, S, Toledo-Patino, S, Goetz, S.K, Farias-Rico, J.A, Hocker, B. | Deposit date: | 2023-08-08 | Release date: | 2024-04-10 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular handcraft of a well-folded protein chimera. Febs Lett., 598, 2024
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8TQS
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8KCI
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![BU of 8kci by Molmil](/molmil-images/mine/8kci) | ATP-bound hMRP5 outward-open | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 5, MAGNESIUM ION | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-08-07 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8Q4G
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![BU of 8q4g by Molmil](/molmil-images/mine/8q4g) | Thin filament from FIB milled relaxed left ventricular mouse myofibrils | Descriptor: | Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain | Authors: | Tamborrini, D, Wang, Z, Wagner, T, Tacke, S, Stabrin, M, Grange, M, Kho, A.L, Bennet, P, Rees, M, Gautel, M, Raunser, S. | Deposit date: | 2023-08-06 | Release date: | 2023-11-01 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structure of the native myosin filament in the relaxed cardiac sarcomere. Nature, 623, 2023
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8Q3O
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8Q3Q
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8Q3N
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8Q3P
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8TPL
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![BU of 8tpl by Molmil](/molmil-images/mine/8tpl) | ATP-2 state of Bcs1 (unsymmetrized) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-08-04 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8TP1
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![BU of 8tp1 by Molmil](/molmil-images/mine/8tp1) | ATP-2 state of Bcs1 (C7 symmetrized) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | Authors: | Zhan, J, Xia, D. | Deposit date: | 2023-08-04 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
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8Q3L
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