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1AC9
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SOLUTION STRUCTURE OF A DNA DECAMER CONTAINING THE ANTIVIRAL DRUG GANCICLOVIR: COMBINED USE OF NMR, RESTRAINED MOLECULAR DYNAMICS, AND FULL RELAXATION REFINEMENT, 6 STRUCTURES
Descriptor: DNA
Authors:Foti, M, Marshalko, S, Schurter, E, Kumar, S, Beardsley, G.P, Schweitzer, B.I.
Deposit date:1997-02-17
Release date:1997-07-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a DNA decamer containing the antiviral drug ganciclovir: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement.
Biochemistry, 36, 1997
3JRG
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BU of 3jrg by Molmil
Crystal structure of Fis bound to 27 bp non consensus sequence DNA F18
Descriptor: DNA (27-MER), DNA-binding protein fis
Authors:Stella, S, Cascio, D, Johnson, R.C.
Deposit date:2009-09-08
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:The shape of the DNA minor groove directs binding by the DNA-bending protein Fis.
Genes Dev., 24, 2010
3JRE
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BU of 3jre by Molmil
Crystal structure of Fis bound to 27 bp DNA F26 containing A-tract at center
Descriptor: DNA (27-MER), DNA-binding protein fis
Authors:Stella, S, Cascio, D, Johnson, R.C.
Deposit date:2009-09-08
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:The shape of the DNA minor groove directs binding by the DNA-bending protein Fis.
Genes Dev., 24, 2010
3JTG
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BU of 3jtg by Molmil
Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA
Descriptor: DNA (5'-D(*CP*AP*AP*AP*CP*AP*GP*GP*AP*AP*AP*CP*TP*CP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*GP*TP*TP*TP*CP*CP*TP*GP*TP*TP*T)-3'), ETS-related transcription factor Elf-3
Authors:Tahirov, T.H, Babayeva, N.D, Agarkar, V.B, Rizzino, A.
Deposit date:2009-09-11
Release date:2010-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA.
J.Mol.Biol., 397, 2010
4LJR
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BU of 4ljr by Molmil
Structural insights into the unique single-stranded DNA binding mode of DNA processing protein A from Helicobacter pylori
Descriptor: DNA processing chain A, single-stranded DNA
Authors:Wang, W.
Deposit date:2013-07-05
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Nucleic Acids Res., 42, 2014
7O56
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BU of 7o56 by Molmil
X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element solved by Phosphorus and Sulphur SAD methods
Descriptor: DNA (5'-D(P*AP*AP*TP*AP*AP*AP*AP*GP*AP*AP*AP*CP*CP*GP*AP*AP*AP*GP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP*TP*CP*TP*TP*TP*TP*AP*T)-3'), Interferon regulatory factor 4
Authors:El Omari, K, Agnarelli, A, Duman, R, Wagner, A, Mancini, E.J.
Deposit date:2021-04-07
Release date:2021-05-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Phosphorus and sulfur SAD phasing of the nucleic acid-bound DNA-binding domain of interferon regulatory factor 4.
Acta Crystallogr.,Sect.F, 77, 2021
4LJL
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BU of 4ljl by Molmil
Structural insights into the unique single-stranded DNA binding mode of DNA processing protein A from Helicobacter pylori
Descriptor: DNA processing chain A (DprA)
Authors:Wang, W.
Deposit date:2013-07-05
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Nucleic Acids Res., 42, 2014
4LJK
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BU of 4ljk by Molmil
Structural insights into the unique single-stranded DNA binding mode of DNA processing protein A from Helicobacter pylori
Descriptor: DNA processing chain A (DprA)
Authors:Wang, W.
Deposit date:2013-07-05
Release date:2014-01-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.354 Å)
Cite:Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Nucleic Acids Res., 42, 2014
8ICU
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BU of 8icu by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DDATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR)
Descriptor: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*GP*A)-3'), ...
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1995-12-15
Release date:1996-11-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
8ICV
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BU of 8icv by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR)
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*GP*G)-3'), ...
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1996-01-04
Release date:1996-11-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
5JLX
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BU of 5jlx by Molmil
AntpHD with 15bp DNA duplex S-monothioated at Cytidine-8
Descriptor: DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C7S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), Homeotic protein antennapedia, ...
Authors:White, M.A, Zandarashvili, L, Iwahara, J, Nguyen, D.
Deposit date:2016-04-27
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity.
Chembiochem, 17, 2016
9BDX
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BU of 9bdx by Molmil
NF-kappaB RelA homo-dimer bound to CG-centric kappaB DNA
Descriptor: DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*GP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*CP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), Transcription factor p65
Authors:Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G.
Deposit date:2024-04-12
Release date:2024-04-24
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
9BDW
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BU of 9bdw by Molmil
NF-kappaB RelA homo-dimer bound to GC-centric kappaB DNA
Descriptor: DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*AP*GP*T)-3'), SULFATE ION, ...
Authors:Biswas, T, Shahabi, S, Tsodikov, O.V, Huang, D, Ghosh, G.
Deposit date:2024-04-12
Release date:2024-04-24
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
9BDU
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BU of 9bdu by Molmil
NF-kappaB RelA homo-dimer bound to AT-centric kappaB DNA
Descriptor: DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*GP*T)-3'), SULFATE ION, ...
Authors:Biswas, T, Huang, D, Ghosh, G.
Deposit date:2024-04-12
Release date:2024-04-24
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
9BDV
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BU of 9bdv by Molmil
NF-kappaB RelA homo-dimer bound to TA-centric kappaB DNA
Descriptor: DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), SULFATE ION, ...
Authors:Biswas, T, Shahabi, S, Tsodikov, O.V.
Deposit date:2024-04-12
Release date:2024-04-24
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
1L3S
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BU of 1l3s by Molmil
Crystal Structure of Bacillus DNA Polymerase I Fragment complexed to 9 base pairs of duplex DNA.
Descriptor: 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3', DNA Polymerase I, ...
Authors:Johnson, S.J, Taylor, J.S, Beese, L.S.
Deposit date:2002-03-01
Release date:2003-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
Proc.Natl.Acad.Sci.USA, 100, 2003
5JLT
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BU of 5jlt by Molmil
The crystal structure of the bacteriophage T4 MotA C-terminal domain in complex with dsDNA reveals a novel protein-DNA recognition motif
Descriptor: DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*TP*GP*CP*TP*TP*AP*AP*TP*AP*AP*TP*CP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*GP*AP*TP*TP*AP*TP*TP*AP*AP*GP*CP*AP*AP*AP*GP*CP*TP*TP*C)-3'), Middle transcription regulatory protein motA
Authors:Cuypers, M.G, Robertson, R.M, Knipling, L, Hinton, D.M, White, S.W.
Deposit date:2016-04-27
Release date:2017-05-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.955 Å)
Cite:The phage T4 MotA transcription factor contains a novel DNA binding motif that specifically recognizes modified DNA.
Nucleic Acids Res., 46, 2018
9L9W
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BU of 9l9w by Molmil
Structure of SPARTA in complex with guide DNA and a 19nt target DNA
Descriptor: DNA (5'-D(*T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*AP*T)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, ...
Authors:Hu, R, Guo, C, Liu, X, Chen, J, Liu, L.
Deposit date:2024-12-31
Release date:2025-03-12
Method:X-RAY DIFFRACTION (5.87 Å)
Cite:Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system.
Nucleic Acids Res., 53, 2025
9L9X
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BU of 9l9x by Molmil
Structure of SPARTA in complex with guide DNA and a 20nt target DNA
Descriptor: DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*AP*T)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, ...
Authors:Hu, R, Guo, C, Liu, X, Chen, J, Liu, L.
Deposit date:2024-12-31
Release date:2025-03-12
Method:X-RAY DIFFRACTION (6.7 Å)
Cite:Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system.
Nucleic Acids Res., 53, 2025
1LQM
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BU of 1lqm by Molmil
ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE COMPLEX WITH URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN
Descriptor: URACIL-DNA GLYCOSYLASE, URACIL-DNA GLYCOSYLASE INHIBITOR
Authors:Saikrishnan, K, Sagar, M.B, Ravishankar, R, Roy, S, Purnapatre, K, Varshney, U, Vijayan, M.
Deposit date:2002-05-10
Release date:2002-11-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG.
Acta Crystallogr.,Sect.D, 58, 2002
2J8X
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BU of 2j8x by Molmil
Epstein-Barr virus uracil-DNA glycosylase in complex with Ugi from PBS-2
Descriptor: URACIL-DNA GLYCOSYLASE, URACIL-DNA GLYCOSYLASE INHIBITOR, UREA
Authors:Geoui, T, Buisson, M, Tarbouriech, N, Burmeister, W.P.
Deposit date:2006-10-31
Release date:2006-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:New Insights on the Role of the Gamma-Herpesvirus Uracil-DNA Glycosylase Leucine Loop Revealed by the Structure of the Epstein-Barr Virus Enzyme in Complex with an Inhibitor Protein.
J.Mol.Biol., 366, 2007
1L3U
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BU of 1l3u by Molmil
Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 11 base pairs of duplex DNA following addition of a dTTP and a dATP residue.
Descriptor: 5'-D(*GP*AP*C*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3', DNA Polymerase I, ...
Authors:Johnson, S.J, Taylor, J.S, Beese, L.S.
Deposit date:2002-03-01
Release date:2003-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
Proc.Natl.Acad.Sci.USA, 100, 2003
1L5U
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BU of 1l5u by Molmil
Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 12 base pairs of duplex DNA following addition of a dTTP, a dATP, and a dCTP residue.
Descriptor: 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3', DNA Polymerase I, ...
Authors:Johnson, S.J, Taylor, J.S, Beese, L.S.
Deposit date:2002-03-08
Release date:2003-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
Proc.Natl.Acad.Sci.USA, 100, 2003
3K4X
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BU of 3k4x by Molmil
Eukaryotic Sliding Clamp PCNA Bound to DNA
Descriptor: DNA (5'-D(*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), Proliferating cell nuclear antigen
Authors:McNally, R, Kuriyan, J.
Deposit date:2009-10-06
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Analysis of the role of PCNA-DNA contacts during clamp loading.
Bmc Struct.Biol., 10, 2010
3S6I
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BU of 3s6i by Molmil
Schizosaccaromyces pombe 3-methyladenine DNA glycosylase (Mag1) in complex with abasic-DNA.
Descriptor: (5'-D(*AP*AP*GP*AP*CP*TP*TP*GP*GP*AP*C)-3'), (5'-D(*TP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*T)-3'), DNA-3-methyladenine glycosylase 1, ...
Authors:Adhikary, S, Eichman, B.F.
Deposit date:2011-05-25
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Analysis of substrate specificity of Schizosaccharomyces pombe Mag1 alkylpurine DNA glycosylase.
Embo Rep., 12, 2011

238582

數據於2025-07-09公開中

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