7AIF
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![BU of 7aif by Molmil](/molmil-images/mine/7aif) | HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND L-GLUTAMATE TENOFOVIR WITH BOUND MANGANESE | Descriptor: | DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(P*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3'), Gag-Pol polyprotein, ... | Authors: | Gu, W, Martinez, S.E, Nguyen, H, Xu, H, Herdewijn, P, de Jonghe, S, Das, K. | Deposit date: | 2020-09-27 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues. J.Med.Chem., 64, 2021
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3MGV
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![BU of 3mgv by Molmil](/molmil-images/mine/3mgv) | Cre recombinase-DNA transition state | Descriptor: | DNA (5'-D(*CP*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), Recombinase cre, ... | Authors: | Gibb, B.P, Gupta, K, Ghosh, K, Sharp, R, Chen, J, Van Duyne, G.D. | Deposit date: | 2010-04-07 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Requirements for catalysis in the Cre recombinase active site. Nucleic Acids Res., 38, 2010
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6W1A
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![BU of 6w1a by Molmil](/molmil-images/mine/6w1a) | |
1AB4
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7AIG
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![BU of 7aig by Molmil](/molmil-images/mine/7aig) | HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND L-GLUTAMATE TENOFOVIR | Descriptor: | DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(P*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3'), Gag-Pol polyprotein, ... | Authors: | Gu, W, Martinez, S.E, Nguyen, H, Xu, H, Herdewijn, P, de Jonghe, S, Das, K. | Deposit date: | 2020-09-27 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues. J.Med.Chem., 64, 2021
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1LCD
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![BU of 1lcd by Molmil](/molmil-images/mine/1lcd) | STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), Lac Repressor, ... | Authors: | Chuprina, V.P, Rullmann, J.A.C, Lamerichs, R.M.J.N, Van Boom, J.H, Boelens, R, Kaptein, R. | Deposit date: | 1993-03-25 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. J.Mol.Biol., 234, 1993
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5Z2V
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![BU of 5z2v by Molmil](/molmil-images/mine/5z2v) | Crystal structure of RecR from Pseudomonas aeruginosa PAO1 | Descriptor: | ANY 5'-MONOPHOSPHATE NUCLEOTIDE, GLYCEROL, PHOSPHATE ION, ... | Authors: | Che, S, Zhang, Q, Bartlam, M. | Deposit date: | 2018-01-04 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of RecR, a member of the RecFOR DNA-repair pathway, from Pseudomonas aeruginosa PAO1. Acta Crystallogr F Struct Biol Commun, 74, 2018
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4E7L
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4E7K
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![BU of 4e7k by Molmil](/molmil-images/mine/4e7k) | PFV integrase Target Capture Complex (TCC-Mn), freeze-trapped prior to strand transfer, at 3.0 A resolution | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*CP*CP*CP*GP*AP*GP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*CP*TP*CP*GP*GP*G)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... | Authors: | Maertens, G.N, Cherepanov, P. | Deposit date: | 2012-03-17 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo. Embo J., 31, 2012
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4HIK
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![BU of 4hik by Molmil](/molmil-images/mine/4hik) | |
8HWH
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![BU of 8hwh by Molmil](/molmil-images/mine/8hwh) | Cryo-EM Structure of D5 Apo-ssDNA form | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Primase D5 | Authors: | Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H. | Deposit date: | 2022-12-29 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus. Nat.Struct.Mol.Biol., 31, 2024
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7Q94
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![BU of 7q94 by Molmil](/molmil-images/mine/7q94) | Crystal Structure of Agrobacterium tumefaciens NADQ, DNA complex. | Descriptor: | DNA binding region (31-MER), NADQ transcription factor | Authors: | Cianci, M, Minazzato, G, Heroux, A, Raffaelli, N, Sorci, L, Gasparrini, M. | Deposit date: | 2021-11-11 | Release date: | 2022-11-09 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis. J.Struct.Biol., 214, 2022
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6W1F
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![BU of 6w1f by Molmil](/molmil-images/mine/6w1f) | |
4TR6
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![BU of 4tr6 by Molmil](/molmil-images/mine/4tr6) | Crystal structure of DNA polymerase sliding clamp from Bacillus subtilis | Descriptor: | DNA polymerase III subunit beta, SODIUM ION | Authors: | Burnouf, D, Olieric, V, Ennifar, E, Wolff, P. | Deposit date: | 2014-06-14 | Release date: | 2014-09-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins. J.Med.Chem., 57, 2014
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4E7H
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![BU of 4e7h by Molmil](/molmil-images/mine/4e7h) | PFV intasome prior to 3'-processing, Apo form (UI-Apo) | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*AP*AP*T)-3'), GLYCEROL, ... | Authors: | Hare, S, Cherepanov, P. | Deposit date: | 2012-03-17 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5701 Å) | Cite: | 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo. Embo J., 31, 2012
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6USO
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![BU of 6uso by Molmil](/molmil-images/mine/6uso) | |
6USP
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![BU of 6usp by Molmil](/molmil-images/mine/6usp) | Telomerase Reverse Transcriptase product complex, TERT:DNA | Descriptor: | DNA (5'-D(P*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*G)-3'), DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*CP*T)-R(P*GP*AP*C)-D(P*C)-3'), MAGNESIUM ION, ... | Authors: | Schaich, M.A, Freudenthal, B.D. | Deposit date: | 2019-10-28 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.56 Å) | Cite: | Mechanisms of nucleotide selection by telomerase. Elife, 9, 2020
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2Y9Z
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![BU of 2y9z by Molmil](/molmil-images/mine/2y9z) | Chromatin Remodeling Factor ISW1a(del_ATPase) in DNA complex | Descriptor: | I-DNA/E-DNA, IMITATION SWITCH PROTEIN 1 (DEL_ATPASE), ISWI ONE COMPLEX PROTEIN 3 | Authors: | Yamada, K, Frouws, T.D, Angst, B, Fitzgerald, D.J, DeLuca, C, Schimmele, K, Sargent, D.F, Richmond, T.J. | Deposit date: | 2011-02-17 | Release date: | 2011-04-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.601 Å) | Cite: | Structure and Mechanism of the Chromatin Remodelling Factor Isw1A Nature, 472, 2011
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4HQE
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![BU of 4hqe by Molmil](/molmil-images/mine/4hqe) | The crystal structure of QsrR-DNA complex | Descriptor: | DNA (5'-D(*AP*GP*TP*AP*TP*AP*AP*TP*TP*AP*TP*TP*AP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*TP*AP*AP*TP*AP*AP*TP*TP*AP*TP*AP*CP*T)-3'), Transcriptional regulator QsrR | Authors: | He, C, Ji, Q, Zhang, L. | Deposit date: | 2012-10-25 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc.Natl.Acad.Sci.USA, 110, 2013
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6USQ
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![BU of 6usq by Molmil](/molmil-images/mine/6usq) | Telomerase Reverse Transcriptase binary complex with Y256A mutation, TERT:DNA | Descriptor: | DNA (5'-D(*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*GP*GP*TP*CP*A)-3'), DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*CP*T)-R(P*GP*AP*C)-D(P*C)-3'), MAGNESIUM ION, ... | Authors: | Schaich, M.A, Freudenthal, B.D, Khoang, T.H. | Deposit date: | 2019-10-28 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Mechanisms of nucleotide selection by telomerase. Elife, 9, 2020
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4HJ8
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4HJA
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4HJ7
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4HIO
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4HJ9
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![BU of 4hj9 by Molmil](/molmil-images/mine/4hj9) | |