3MGV

Cre recombinase-DNA transition state

Summary for 3MGV

• Entry DOI: 10.2210/pdb3mgv/pdb
• Related: 1CRX 2HOF 2HOI 4CRX
• Descriptor: Recombinase cre, DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), DNA (5'-D(*CP*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), ... (5 entities in total)
• Functional Keywords: cre-loxp, transition state, isomerase-dna complex, isomerase/dna
• Biological source: Enterobacteria phage P1 (Bacteriophage P1)
• Total number of polymer chains: 12
• Total formula weight: 197470.58

Authors

Gibb, B.P.,Gupta, K.,Ghosh, K.,Sharp, R.,Chen, J.,Van Duyne, G.D. (deposition date: 2010-04-07, release date: 2010-05-26, Last modification date: 2023-09-06)

• Primary citation: Gibb, B.,Gupta, K.,Ghosh, K.,Sharp, R.,Chen, J.,Van Duyne, G.D.; Requirements for catalysis in the Cre recombinase active site.; Nucleic Acids Res., 38:5817-5832, 2010; PubMed: 20462863; DOI: 10.1093/nar/gkq384

Experimental method

X-RAY DIFFRACTION (2.29 Å)