PDB: 225158 resultsInfo pagesStatus searchChemie searchBIRD

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9BFN	Cryo-EM co-structure of AcrB with the CU232 efflux pump inhibitor Descriptor: (2R)-1-(4-aminopiperidin-1-yl)-3-[3-(trifluoromethyl)phenoxy]propan-2-ol, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Multidrug efflux pump subunit AcrB Authors: Su, C.C. Deposit date: 2024-04-18 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
9BFM	Cryo-EM co-structure of AcrB with the EPM35 efflux pump inhibitor Descriptor: (2S)-1-(3,4-dichlorophenoxy)-3-(4-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}piperidin-1-yl)propan-2-ol, Multidrug efflux pump subunit AcrB Authors: Su, C.C. Deposit date: 2024-04-18 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
9BFL	Solution structure of the scorpion toxin omega-Buthitoxin-Hf1a Descriptor: Buthitoxin-Hf1a Authors: Rosengren, K.J, Payne, C.D. Deposit date: 2024-04-18 Release date: 2024-06-05 Method: SOLUTION NMR Cite: Novel Scorpion Toxin omega-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via Ca V 3.3 and Ca V 3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain. Int J Mol Sci, 25, 2024
9BFH	Cryo-EM co-structure of AcrB with the CU032 efflux pump inhibitor Descriptor: (2S)-1-[(3R)-3-aminopyrrolidin-1-yl]-3-(3,4-dichlorophenoxy)propan-2-ol, Multidrug efflux pump subunit AcrB Authors: Su, C.C. Deposit date: 2024-04-17 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (2.62 Å) Cite: Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023
9BFB	Crystal structure of BRAF kinase domain with PF-07284890 Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, N-{2-chloro-3-[(3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-fluorophenyl}-3-fluoropropane-1-sulfonamide, ... Authors: Mou, T.-C. Deposit date: 2024-04-17 Release date: 2024-08-14 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Identification of the Clinical Candidate PF-07284890 ( ARRY-461 ), a Highly Potent and Brain Penetrant BRAF Inhibitor for the Treatment of Cancer. J.Med.Chem., 67, 2024
9BF6	Cryo-EM structure of the HIV-1 WITO IDL Env trimer in complex with PGT122 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2024-04-16 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43, 2024
9BF5	Structure of V. cholerae DdmD in complex with ssDNA Descriptor: Helicase/UvrB N-terminal domain-containing protein, ssDNA1, ssDNA2 Authors: Shen, Z.F, Yang, X.Y, Fu, T.M. Deposit date: 2024-04-16 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (3.07 Å) Cite: DdmDE eliminates plasmid invasion by DNA-guided DNA targeting. Cell, 2024
9BF2	MID domain of Ago2 bound to UMP Descriptor: Protein argonaute-2, URIDINE-5'-MONOPHOSPHATE Authors: Harp, J.M, Egli, M. Deposit date: 2024-04-16 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
9BF1	Structure of apo-state V. cholerae DdmD Descriptor: Helicase/UvrB N-terminal domain-containing protein Authors: Shen, Z.F, Yang, X.Y, Fu, T.M. Deposit date: 2024-04-16 Release date: 2024-08-21 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: DdmDE eliminates plasmid invasion by DNA-guided DNA targeting. Cell, 2024
9BF0	MID domain of human Argo2 bound to UTP Descriptor: Protein argonaute-2, URIDINE 5'-TRIPHOSPHATE Authors: Harp, J.M, Egli, M. Deposit date: 2024-04-16 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
9BEZ	MID domain of human Argo2 bound to RNA Descriptor: Protein argonaute-2, [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate Authors: Harp, J.M, Egli, M. Deposit date: 2024-04-16 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
9BEW	Cryo-EM structure of the HIV-1 BG505 IDL Env trimer in complex with 3BNC117 and 10-1074 Fabs Descriptor: 10-1074 heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2024-04-16 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43, 2024
9BER	Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2024-04-16 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43, 2024
9BEO	Tungstate binding protein (Tungbindin) from Eubacterium limosum with 7.5 tungstates bound Descriptor: Molybdenum-pterin binding domain-containing protein, TUNGSTATE(VI)ION Authors: Zhou, D, Rose, J.P, Chen, L, Wang, B.C. Deposit date: 2024-04-16 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Tungstate binding protein (Tungbindin) from Eubacterium limosum with 7.5 tungstates bound To Be Published
9BEM	Tungstate binding protein (Tungbindin) from Eubacterium limosum with seven Tungstates bound Descriptor: Molybdenum-pterin-binding protein, SULFATE ION, TUNGSTATE(VI)ION Authors: Zhou, D, Rose, J.P, Chen, L, Wang, B.C. Deposit date: 2024-04-15 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Tungstate binding protein (Tungbindin) from Eubacterium limosum with seven Tungstates bound To Be Published
9BEL	Tungstate binding protein (Tungbindin) from Eubacterium limosum with five Tungstates bound Descriptor: Molybdenum-pterin binding domain-containing protein, SULFATE ION, TUNGSTATE(VI)ION Authors: Zhou, D, Rose, J.P, Chen, L, Wang, B.C. Deposit date: 2024-04-15 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Tungstate binding protein (Tungbindin) from Eubacterium limosum with five Tungstates bound To Be Published
9BEI	Cryo-EM structure of synthetic claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-2, and Nanobody Descriptor: Anti-fab nanobody, COP-2 Fab Heavy chain, COP-2 Fab Light chain, ... Authors: Vecchio, A.J. Deposit date: 2024-04-15 Release date: 2024-04-24 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: Computational design of soluble and functional membrane protein analogues. Nature, 631, 2024
9BED	Tungstate binding protein (Tungbindin) from Eubacterium limosum with eight molybdates bound Descriptor: MOLYBDATE ION, Molybdenum-pterin-binding protein Authors: Zhou, D, Rose, J.P, Chen, L, Wang, B.C. Deposit date: 2024-04-15 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Tungstate binding protein (Tungbindin) from Eubacterium limosum with eight molybdates bound To Be Published
9BEB	Tungstate binding protein (Tungbindin) from Eubacterium limosum with eight Tungstates bound Descriptor: Molybdenum-pterin binding domain-containing protein, TUNGSTATE(VI)ION Authors: Zhou, D, Rose, J.P, Chen, L, Wang, B.C. Deposit date: 2024-04-15 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Tungstate binding protein (Tungbindin) from Eubacterium limosum with eight Tungstates bound To be published
9BE2	Structure of the E. coli nucleic associated protein, YejK Descriptor: Nucleoid-associated protein YejK Authors: Schumacher, M.A. Deposit date: 2024-04-13 Release date: 2024-05-15 Last modified: 2024-07-24 Method: X-RAY DIFFRACTION (3.56 Å) Cite: Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp. Nucleic Acids Res., 52, 2024
9BE1	CG-centric NF-kappaB RelA binding DNA Descriptor: ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*G)-3'), ZINC ION Authors: Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G. Deposit date: 2024-04-13 Release date: 2024-08-07 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
9BE0	GC-centric NF-kappaB RelA binding DNA Descriptor: ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*G)-3'), ZINC ION Authors: Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. Deposit date: 2024-04-13 Release date: 2024-08-07 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
9BDZ	TA-centric NF-kappaB RelA binding DNA Descriptor: ACETATE ION, ZINC ION, double-stranded DNA Authors: Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G. Deposit date: 2024-04-13 Release date: 2024-08-07 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
9BDY	AT-centric NF-kappaB RelA binding DNA Descriptor: ACETATE ION, DNA (5'-D(*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*G)-3'), ... Authors: Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. Deposit date: 2024-04-13 Release date: 2024-08-07 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
9BDX	NF-kappaB RelA homo-dimer bound to CG-centric kappaB DNA Descriptor: DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*GP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*CP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), Transcription factor p65 Authors: Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. Deposit date: 2024-04-12 Release date: 2024-04-24 Last modified: 2024-06-12 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024

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