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8SZC	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-1HT/ATP Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Tang, Q, Mchaourab, H. Deposit date: 2023-05-29 Release date: 2023-11-15 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8T3K	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP2 Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ... Authors: Tang, Q, Mchaourab, H. Deposit date: 2023-06-07 Release date: 2023-11-29 Method: ELECTRON MICROSCOPY (3.33 Å) Cite: Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8SX9	Inward-facing narrow conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc Descriptor: Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX8	Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc Descriptor: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SXB	Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc Descriptor: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Multidrug resistance-associated protein 4 isoform X1 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX7	Bovine multidrug resistance protein 4 (MRP4) bound to DHEA-S in MSP lipid nanodisc Descriptor: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SWN	Bovine multidrug resistance protein 4 (MRP4) E1202Q mutant bound to ATP in MSP lipid nanodisc Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP binding cassette subfamily C member 4, MAGNESIUM ION, ... Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-19 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SXA	Inward-facing wide conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc Descriptor: Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8TI1	Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... Authors: Driggers, C.M, Shyng, S.-L. Deposit date: 2023-07-18 Release date: 2024-04-03 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nat Commun, 15, 2024
8TI2	Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... Authors: Driggers, C.M, Shyng, S.-L. Deposit date: 2023-07-18 Release date: 2024-04-03 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nat Commun, 15, 2024
8SQL	Cleaved Ycf1p Monomer in the Beta Conformation Descriptor: Metal resistance protein YCF1, PHOSPHATIDYLETHANOLAMINE, Unknown peptide from Ycf1p R region Authors: Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V. Deposit date: 2023-05-04 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cleaved Ycf1p Monomer in the Beta Conformation To Be Published
8SQM	Cleaved Ycf1p Monomer in the IFwide-alpha conformation Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, Metal resistance protein YCF1, Unknown peptide from Ycf1p R region Authors: Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V. Deposit date: 2023-05-04 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of a dimeric ABC transporter To Be Published
8SQ0	Cleaved Ycf1p Dimer in the IFwide-beta conformation Descriptor: (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12E)-hexadeca-9,12-dienoate, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Metal resistance protein YCF1, ... Authors: Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V. Deposit date: 2023-05-04 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of a dimeric ABC transporter To Be Published
8T4H	Transporter associated with antigen processing (TAP) bound to the 8-mer peptide RRYQSTEL Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, Synthetic 8-mer peptide Authors: Lee, J, Chen, J. Deposit date: 2023-06-09 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Transporter associated with antigen processing (TAP) bound to the 8-mer peptide RRYQSTEL To Be Published
8T46	Transporter associated with antigen processing (TAP) in the apo state Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2 Authors: Lee, J, Oldham, M.L, Chen, J. Deposit date: 2023-06-08 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Principles of peptide selection by the transporter associated with antigen processing. Proc.Natl.Acad.Sci.USA, 121, 2024
8T4G	Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, HLA-C4 specific peptide Authors: Lee, J, Oldham, M.L, Chen, J. Deposit date: 2023-06-09 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL To Be Published
8T4F	Transporter associated with antigen processing (TAP) bound to the 9-mer peptide RRYQKSTEL Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, Histone H3.3C peptide Authors: Lee, J, Oldham, M.L, Chen, J. Deposit date: 2023-06-09 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Transporter associated with antigen processing (TAP) bound to the 9-mer peptide RRYQKSTEL To Be Published
8T4I	Transporter associated with antigen processing (TAP) bound to the 7-mer peptide RRYSTEL Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, Synthetic 7-mer peptide Authors: Lee, J, Oldham, M.L, Chen, J. Deposit date: 2023-06-09 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (5.1 Å) Cite: Transporter associated with antigen processing (TAP) bound to the 7-mer peptide RRYSTEL To Be Published
8T4J	Transporter associated with antigen processing (TAP) bound to the 14-mer peptide LPAVVGLSPGEQEY Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, HLA-B35 specific peptide Authors: Lee, J, Oldham, M.L, Chen, J. Deposit date: 2023-06-09 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Transporter associated with antigen processing (TAP) bound to the 14-mer peptide LPAVVGLSPGEQEY To Be Published
8T4E	Transporter associated with antigen processing (TAP) bound to the 9-mer peptide ILKEPVHGV Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, Transframe peptide Authors: Lee, J, Oldham, M.L, Chen, J. Deposit date: 2023-06-09 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Transporter associated with antigen processing (TAP) bound to the 9-mer peptide ILKEPVHGV To Be Published
8U2C	Gaussian mixture model based single particle refinement - ABC transporter (inhibitor-bound ABCG2 from EMPIAR-10374) Descriptor: 5D3 Fab heavy chain variable domain, 5D3 Fab light chain variable domain, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... Authors: Chen, M, Pintilie, G. Deposit date: 2023-09-05 Release date: 2023-11-15 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21, 2024
8TZL	Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, full-length Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... Authors: Hao, A, Lee, S.-Y. Deposit date: 2023-08-27 Release date: 2023-12-20 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.55 Å) Cite: Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae. Structure, 32, 2024
8TZJ	Cryo-EM structure of Vibrio cholerae FtsE/FtsX complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... Authors: Hao, A, Lee, S.-Y. Deposit date: 2023-08-27 Release date: 2023-12-20 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.51 Å) Cite: Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae. Structure, 32, 2024
8TZK	Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, shortened Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... Authors: Hao, A, Lee, S.-Y. Deposit date: 2023-08-27 Release date: 2023-12-20 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.55 Å) Cite: Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae. Structure, 32, 2024
8UFH	Acinetobacter baylyi LptB2FG bound to Acinetobacter baylyi lipopolysaccharide and a macrocyclic peptide Descriptor: (2~{R},4~{R},5~{R},6~{R})-2-[(2~{R},4~{R},5~{R},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4-[(2~{R},3~{R},4~{R},5~{S},6~{S})-3-acetamido-6-carboxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-5-oxidanyl-oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{S})-3-dodecanoyloxydodecanoyl]oxy-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-heptanoyloxynonanoyl]amino]-3-oxidanyl-4-[(3~{R})-3-oxidanyloctanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-5-[[(3~{S})-3-[(3~{R})-3-oxidanyldodecanoyl]oxydecanoyl]amino]-3-phosphonooxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, (7S,10S,13S,17P)-10-(4-aminobutyl)-7-(3-aminopropyl)-17-(6-aminopyridin-3-yl)-20-chloro-13-[(1H-indol-3-yl)methyl]-12-methyl-6,7,9,10,12,13,15,16-octahydropyrido[2,3-b][1,5,8,11,14]benzothiatetraazacycloheptadecine-8,11,14(5H)-trione, LPS export ABC transporter permease LptG, ... Authors: Pahil, K.S, Gilman, M.S.A, Baidin, V, Kruse, A.C, Kahne, D. Deposit date: 2023-10-04 Release date: 2024-01-03 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature, 625, 2024

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