Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1XP1
DownloadVisualize
BU of 1xp1 by Molmil
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 15
Descriptor: (2S,3R)-2-(4-{2-[(3R,4R)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6- OL, Estrogen receptor
Authors:Fitzgerald, P.M.D, Sharma, N.
Deposit date:2004-10-07
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Bioorg.Med.Chem.Lett., 15, 2005
1XVP
DownloadVisualize
BU of 1xvp by Molmil
crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO
Descriptor: 6-(4-CHLOROPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBALDEHYDE O-(3,4-DICHLOROBENZYL)OXIME, Orphan nuclear receptor NR1I3, PENTADECANOIC ACID, ...
Authors:Xu, R.X, Lambert, M.H, Wisely, B.B, Warren, E.N, Weinert, E.E, Waitt, G.M, Williams, J.D, Moore, L.B, Willson, T.M, Moore, J.T.
Deposit date:2004-10-28
Release date:2004-12-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer.
Mol.Cell, 16, 2004
1XJ7
DownloadVisualize
BU of 1xj7 by Molmil
Complex Androgen Receptor LBD and RAC3 peptide
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, RAC3 derived peptide
Authors:Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Buehrer, B.M, Webb, P, Fletterick, R.J, Guy, R.K.
Deposit date:2004-09-22
Release date:2005-01-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor
J.Biol.Chem., 280, 2005
1XPC
DownloadVisualize
BU of 1xpc by Molmil
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 19
Descriptor: (2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLIDIN-1-YLPROPYL]OXY}PHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL, Estrogen receptor
Authors:Fitzgerald, P.M.D, Sharma, N.
Deposit date:2004-10-08
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Bioorg.Med.Chem.Lett., 15, 2005
1XP9
DownloadVisualize
BU of 1xp9 by Molmil
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 18
Descriptor: (2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2S)-2-PYRROLIDIN-1-YLPROPYL]OXY}PHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL, Estrogen receptor
Authors:Fitzgerald, P.M.D, Sharma, N.
Deposit date:2004-10-08
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Bioorg.Med.Chem.Lett., 15, 2005
1XNN
DownloadVisualize
BU of 1xnn by Molmil
CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN T877A MUTANT COMPLEX WITH (3A-ALPHA-,4-ALPHA 7-ALPHA-,7A-ALPHA-)-3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE.
Descriptor: Androgen receptor, REL-(3AR,4S,7R,7AS)-3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE
Authors:Sack, J.
Deposit date:2004-10-05
Release date:2005-10-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists.
Bioorg.Med.Chem.Lett., 15, 2005
7CXE
DownloadVisualize
BU of 7cxe by Molmil
The ligand-free structure of human PPARgamma LBD R280C mutant
Descriptor: Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
7CXK
DownloadVisualize
BU of 7cxk by Molmil
The ligand-free structure of human PPARgamma LBD R288H mutant in the presence of the SRC-1 coactivator peptide
Descriptor: 16-mer peptide from Nuclear receptor coactivator 1, MALONATE ION, Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
7CXI
DownloadVisualize
BU of 7cxi by Molmil
The ligand-free structure of human PPARgamma LBD F287Y mutant in the presence of the SRC-1 coactivator peptide
Descriptor: 16-mer peptide from Nuclear receptor coactivator 1, MALONATE ION, Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
7CXH
DownloadVisualize
BU of 7cxh by Molmil
The ligand-free structure of human PPARgamma LBD Q286E mutant in the presence of the SRC-1 coactivator peptide
Descriptor: 16-mer peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
7CXF
DownloadVisualize
BU of 7cxf by Molmil
The ligand-free structure of human PPARgamma LBD C285Y mutant in the presence of the SRC-1 coactivator peptide
Descriptor: 16-mer peptide from Nuclear receptor coactivator 1, MALONIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
7CXJ
DownloadVisualize
BU of 7cxj by Molmil
The ligand-free structure of human PPARgamma LBD R288C mutant in the presence of the SRC-1 coactivator peptide
Descriptor: 16-mer peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
7CXG
DownloadVisualize
BU of 7cxg by Molmil
The ligand-free structure of human PPARgamma LBD Q286E mutant
Descriptor: GLYCEROL, Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
7CXL
DownloadVisualize
BU of 7cxl by Molmil
The ligand-free structure of human PPARgamma LBD S289C mutant in the presence of the SRC-1 coactivator peptide
Descriptor: 16-mer peptide from Nuclear receptor coactivator 1, MALONIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Jang, D.M, Han, B.W.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The ligand-free structure of human PPARgamma LBD
To Be Published
1XIU
DownloadVisualize
BU of 1xiu by Molmil
Crystal structure of the agonist-bound ligand-binding domain of Biomphalaria glabrata RXR
Descriptor: (9cis)-retinoic acid, Nuclear receptor coactivator 1, RXR-like protein
Authors:De Groot, A, De Rosny, E, Juillan-Binard, C, Ferrer, J.-L, Laudet, V, Pebay-Peroula, E, Fontecilla-Camps, J.-C, Borel, F.
Deposit date:2004-09-22
Release date:2005-09-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a Novel Tetrameric Complex of Agonist-bound Ligand-binding Domain of Biomphalaria glabrata Retinoid X Receptor.
J.Mol.Biol., 354, 2005
1X76
DownloadVisualize
BU of 1x76 by Molmil
CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-697
Descriptor: 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1
Authors:Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
1X7E
DownloadVisualize
BU of 1x7e by Molmil
CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED WITH WAY-244
Descriptor: Estrogen receptor 1 (alpha), [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE, steroid receptor coactivator-3
Authors:Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
1XNX
DownloadVisualize
BU of 1xnx by Molmil
Crystal structure of constitutive androstane receptor
Descriptor: 16,17-ANDROSTENE-3-OL, constitutive androstane receptor
Authors:Fernandez, E.
Deposit date:2004-10-05
Release date:2005-01-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the murine constitutive androstane receptor complexed to androstenol; a molecular basis for inverse agonism
Mol.Cell, 16, 2004
1XP6
DownloadVisualize
BU of 1xp6 by Molmil
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 16
Descriptor: (2S,3R)-2-(4-{2-[(3S,4S)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL, Estrogen receptor
Authors:Fitzgerald, P.M.D, Sharma, N.
Deposit date:2004-10-08
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Bioorg.Med.Chem.Lett., 15, 2005
1XQC
DownloadVisualize
BU of 1xqc by Molmil
X-ray structure of ERalpha LBD bound to a tetrahydroisoquinoline SERM ligand at 2.05A resolution
Descriptor: (1S)-1-{4-[(9AR)-OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZIN-2-YL]PHENYL}-2-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLIN-6-OL, Estrogen receptor
Authors:Renaud, J, Bischoff, S.F, Buhl, T, Floersheim, P, Fournier, B, Geiser, M, Halleux, C, Kallen, J, Keller, H.J, Ramage, P.
Deposit date:2004-10-12
Release date:2005-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Selective Estrogen Receptor Modulators with Conformationally Restricted Side Chains. Synthesis and Structure-Activity Relationship of ERalpha-Selective Tetrahydroisoquinoline Ligands
J.Med.Chem., 48, 2005
1XZX
DownloadVisualize
BU of 1xzx by Molmil
Thyroxine-Thyroid Hormone Receptor Interactions
Descriptor: 3,5,3'TRIIODOTHYRONINE, CACODYLATE ION, Thyroid hormone receptor beta-1
Authors:Sandler, B, Webb, P, Apriletti, J.W, Huber, B.R, Togashi, M, Cunha Lima, S.T, Juric, S, Nilsson, S, Wagner, R, Fletterick, R.J, Baxter, J.D.
Deposit date:2004-11-12
Release date:2004-12-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Thyroxine-thyroid hormone receptor interactions.
J.Biol.Chem., 279, 2004
1XV9
DownloadVisualize
BU of 1xv9 by Molmil
crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid, and 5b-pregnane-3,20-dione.
Descriptor: (5BETA)-PREGNANE-3,20-DIONE, Orphan nuclear receptor NR1I3, PENTADECANOIC ACID, ...
Authors:Xu, R.X, Lambert, M.H, Wisely, B.B, Warren, E.N, Weinert, E.E, Waitt, G.M, Williams, J.D, Moore, L.B, Willson, T.M, Moore, J.T.
Deposit date:2004-10-27
Release date:2004-12-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer.
Mol.Cell, 16, 2004
1XQ3
DownloadVisualize
BU of 1xq3 by Molmil
Crystal structure of the human androgen receptor ligand binding domain bound with R1881
Descriptor: (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, androgen receptor
Authors:He, B, Gampe Jr, R.T, Kole, A.J, Hnat, A.T, Stanley, T.B, An, G, Stewart, E.L, Kalman, R.I, Minges, J.T, Wilson, E.M.
Deposit date:2004-10-11
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance
Mol.Cell, 16, 2004
1Y0X
DownloadVisualize
BU of 1y0x by Molmil
Thyroxine-Thyroid Hormone Receptor Interactions
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, CACODYLATE ION, Thyroid hormone receptor beta-1
Authors:Sandler, B, Webb, P, Apriletti, J.W, Huber, B.R, Togashi, M, Cunha Lima, S.T, Juric, S, Nilsson, S, Wagner, R, Fletterick, R.J, Baxter, J.D.
Deposit date:2004-11-16
Release date:2004-12-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Thyroxine-thyroid hormone receptor interactions.
J.Biol.Chem., 279, 2004
1Y0S
DownloadVisualize
BU of 1y0s by Molmil
Crystal structure of PPAR delta complexed with GW2331
Descriptor: (2S)-2-(4-[2-(3-[2,4-DIFLUOROPHENYL]-1-HEPTYLUREIDO)ETHYL]PHENOXY)-2-METHYLBUTYRIC ACID, IODIDE ION, Peroxisome proliferator activated receptor delta, ...
Authors:Takada, I, Yu, R.T, Xu, H.E, Xu, R.X, Lambert, M.H, Montana, V.G, Kliewer, S.A, Evans, R.M, Umesono, K.
Deposit date:2004-11-16
Release date:2005-03-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Alteration of a Single Amino Acid in Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) Generates a PPAR delta Phenotype
MOL.ENDOCRINOL., 14, 2000

221716

數據於2024-06-26公開中

PDB statisticsPDBj update infoContact PDBjnumon